Respiratory News and Research

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Enterprise Therapeutics publishes results of Phase 1 study of ETD001, a novel inhaled ENaC blocker for treatment of Cystic Fibrosis, in The Journal of Cystic Fibrosis

Enterprise Therapeutics Ltd (Enterprise), a biopharmaceutical company dedicated to the discovery and development of novel therapies to improve the lives of people with respiratory diseases, today announced the publication of a peer reviewed study in The Journal of Cystic Fibrsosis.

9 Dec 2025

Early RSV infection turns maternal allergy into a powerful driver of childhood asthma

Early-life RSV infection and parental allergy interact to substantially increase childhood asthma risk, supported by population data from more than 1.5 million children and mechanistic mouse experiments. The study shows that viral infection reprograms neonatal immune responses by altering how maternally transferred allergen-specific antibodies are handled, driving long-term allergic airway disease.

8 Dec 2025

Lubiprostone shows signs of slowing kidney function decline in chronic kidney disease

In adults with stage IIIb–IV chronic kidney disease, the constipation drug lubiprostone did not reduce gut-derived uremic toxins but preserved creatinine-based kidney function over 24 weeks. The benefit was linked to microbiome remodeling, increased polyamine production, and improved mitochondrial function rather than toxin lowering.

8 Dec 2025

Poor dietary iron weakens lung memory T cells after flu infection

Dietary iron deficiency in mice alters lung T cell activation during influenza infection and leads to memory T cells that are present in normal or increased numbers but have impaired antiviral cytokine responses. These functional deficits are most pronounced in lung CD8-positive memory T cells and persist even under optimal recall conditions.

8 Dec 2025

Understanding the health hazards of ultrafine particles emitted by small electric home appliances

Small home appliances equipped with electric heating coils and brushed DC motors, like hair dryers, air fryers and toasters—can emit harmful tiny ultrafine particles that deteriorate indoor air quality.

8 Dec 2025

Genetic variant linked to higher heart failure risk in children with myocarditis

A genetic variant is likely putting some children suffering with myocarditis - inflammation of the heart muscle - at higher risk of developing heart failure, which can be fatal, according to a study published today in Circulation Heart Failure.

5 Dec 2025

Study shows how respiratory rhythm shapes memory processes

First and foremost, we breathe in order to absorb oxygen - but this vital rhythm could also have other functions. Over the past few years, a range of studies have shown that respiration influences neural processes, including the processing of stimuli and memory processes.

5 Dec 2025

Rising nighttime heat is linked to shorter and more disrupted sleep

Higher nighttime temperatures are linked to shorter sleep times and lower sleep quality, especially for people with chronic health conditions, lower socioeconomic status, or those living on the West Coast, according to a new USC study.

4 Dec 2025

Cystic fibrosis patients on triple-drug therapy can safely reduce daily lung treatments

A new multi-site study led by researchers at CU Anschutz shows that people with cystic fibrosis (CF) who start the triple-drug therapy elexacaftor/tezacaftor/ivacaftor (ETI) can safely reduce many of their daily lung treatments while maintaining good health for years.

4 Dec 2025

Microbial warning signs that predict death risk in severe pneumonia

Researchers examine the gut and lung microbiota of severe community-acquired pneumonia patients.

3 Dec 2025

Nearly one million young children die each year due to growth failure worldwide

Nearly one million children around the globe fail to reach their fifth birthday every year due to devastating health consequences linked to child growth failure, making it the third leading risk factor for mortality and morbidity in children under five.

2 Dec 2025

Maternal eating disorders linked to higher asthma and wheezing risks in children

Eating disorders in mums-to-be are linked to a heightened risk of asthma and wheezing in their children, irrespective of the type of disorder, presence of co-existing depression/anxiety, or the timing of their child's exposure, finds research published online in the journal Thorax.

2 Dec 2025

They need a ventilator to stay alive. Getting one can be a nightmare.

On vacation in Mexico last year, Michael DiPlacido passed out twice while scuba diving and again in his hotel. Back in St. Louis, doctors diagnosed him with amyotrophic lateral sclerosis, or ALS, an incurable disease that often requires mechanical ventilation.

2 Dec 2025

Los Angeles wildfires trigger surge in virtual health care usage

When uncontrolled wildfires moved from the foothills above Los Angeles into the densely populated urban areas below in January 2025, evacuation ensued and a thick layer of toxic smoke spread across the region. Air quality plummeted. Local hospitals braced for a surge, but it never came.

1 Dec 2025

Circadian rhythms can influence outcomes related to influenza infections

Researchers at Children's Hospital of Philadelphia (CHOP) found that circadian rhythms – the biological clocks of the body – can influence outcomes related to influenza infections, providing clinicians with insight about how biological processes can be used to optimize care for critically ill patients with respiratory viral infections.

1 Dec 2025

Advances in screening and therapeutics make lung cancer treatable, survivable

For decades, lung cancer has been associated with stigma, anxiety, and loss. Advances in screening, therapeutics, and survivorship have created a new reality; lung cancer is treatable, survivable, and increasingly understood as a chronic disease for many.

1 Dec 2025

Why green tea delivers the strongest health benefits

This review examines tea's health effects, highlighting green tea's benefits for heart health and cognition, and warns about risks in processed tea products.

1 Dec 2025

Treating sleep apnea can lower Parkinson’s disease risk

Researchers report that obstructive sleep apnea increases the risk of Parkinson’s disease however, this risk can be attenuated by positive airway pressure.

1 Dec 2025

New AI tools offer hope for global TB elimination

Researchers have unveiled new AI tools, from smartphone cough analysis to child-friendly screening systems, which could transform how tuberculosis is detected, monitored and prevented.

1 Dec 2025

Early-infancy infection with RSV increases the risk of developing childhood asthma

Belgian scientists from VIB and Ghent University (UGent), together with Danish collaborators, have uncovered compelling evidence that early-infancy infection with respiratory syncytial virus (RSV) significantly increases the risk of developing childhood asthma-especially in children with a family history of allergy or asthma.

29 Nov 2025

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Respiratory News and Research

Enterprise Therapeutics publishes results of Phase 1 study of ETD001, a novel inhaled ENaC blocker for treatment of Cystic Fibrosis, in The Journal of Cystic Fibrosis

Early RSV infection turns maternal allergy into a powerful driver of childhood asthma

Lubiprostone shows signs of slowing kidney function decline in chronic kidney disease

Poor dietary iron weakens lung memory T cells after flu infection

Understanding the health hazards of ultrafine particles emitted by small electric home appliances

Genetic variant linked to higher heart failure risk in children with myocarditis

Study shows how respiratory rhythm shapes memory processes

Rising nighttime heat is linked to shorter and more disrupted sleep

Cystic fibrosis patients on triple-drug therapy can safely reduce daily lung treatments

Microbial warning signs that predict death risk in severe pneumonia

Nearly one million young children die each year due to growth failure worldwide

Maternal eating disorders linked to higher asthma and wheezing risks in children

They need a ventilator to stay alive. Getting one can be a nightmare.

Los Angeles wildfires trigger surge in virtual health care usage

Circadian rhythms can influence outcomes related to influenza infections

Advances in screening and therapeutics make lung cancer treatable, survivable

Why green tea delivers the strongest health benefits

Treating sleep apnea can lower Parkinson’s disease risk

New AI tools offer hope for global TB elimination

Early-infancy infection with RSV increases the risk of developing childhood asthma

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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