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Study unlocks genetic treasure chest for chronic kidney disease

Despite impacting an estimated 850 million people and being responsible for 1 in 60 deaths worldwide, few treatments are available for chronic kidney disease.

12 Aug 2021

Deep learning model can classify intracranial tumors using a single 3D MRI scan

A team of researchers at Washington University School of Medicine have developed a deep learning model that is capable of classifying a brain tumor as one of six common types using a single 3D MRI scan, according to a study published in Radiology: Artificial Intelligence.

11 Aug 2021

New genomic and geological mapping tool may help track the deadliest of foodborne pathogens

Among the deadliest of foodborne pathogens, Listeria monocytogenes soon may become easier to track down in food recalls and other investigations, thanks to a new genomic and geological mapping tool created by Cornell University food scientists.

11 Aug 2021

Fine aerosols generated during talking, singing may play a major role in SARS-CoV-2 transmission

The coronavirus disease 2019 (COVID-19) has been thought to spread primarily when an infected person coughs or sneezes, but little is known about its transmissibility through activities such as breathing, talking, and singing.

11 Aug 2021

A new promising target for broad-spectrum therapeutics against coronaviruses

A recent study by Canadian and US researchers demonstrates how frameshift signals of coronaviruses represent a viable target for developing novel therapeutics with broad-spectrum activity – not only against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), but also other constituents of the coronavirus family. The study is currently available on the bioRxiv* preprint server while it undergoes peer review.

11 Aug 2021

Study shows efficacy of gamma irradiation of SARS-CoV-2 vaccine candidate in mouse model

A new study reports a more rapid method of viral inactivation in an effort to increase the appeal of inactivated viral vaccines against the COVID-19 pandemic.

10 Aug 2021

A multi-scale cryo-correlative platform to image SARS-CoV-2 in Vero cells

A new study describes the cytopathic episodes triggered by SARS-CoV-2 with virus replication processes in frozen-hydrated cells.

9 Aug 2021

Researchers use prime editing to correct cystic fibrosis in cultured human stem cells

Researchers from the group of Hans Clevers (Hubrecht Institute) corrected mutations that cause cystic fibrosis in cultured human stem cells.

9 Aug 2021

Study may provide a new therapeutic target for treatment of LUAD patients

Aging-US published "A novel ferroptosis-related gene signature for prognostic prediction of patients with lung adenocarcinoma" which reported that RNA-seq transcriptome data of LUAD patients were obtained from The Cancer Genome Atlas database.

9 Aug 2021

Genetic testing in ambulatory cardiology clinics can benefit many patients

A person's genetics may hold the key to early intervention in cardiovascular disease, leading to better outcomes in patient care.

9 Aug 2021

Computational study identifies key areas of the SARS-CoV-2 genome prone to mutation

By retrieving 329,942 severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) records from the GISAID database, researchers from a software company in Cambridge described genetic variability of SARS-CoV-2 in order to inform further studies. Their findings are currently available on the bioRxiv* preprint server while it undergoes peer review.

9 Aug 2021

New phylogenomic platform identifies increased recombination rates in SARS-CoV-2

Researchers in the United States, Australia and the UK have developed a novel method that enables the evolutionary ancestry (phylogeny) of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) to be comprehensively searched for recombinant lineages.

8 Aug 2021

New study describes SARS-CoV-2 ExoN enzyme that promotes antiviral resistance

A new study describes the structure of a crucial enzyme present in SARS-CoV-2.

8 Aug 2021

New streamlined approach for high-coverage genome sequencing of single yeast cells

A single cell can reveal much about the biological world through genomic sequencing. Scientists can compare a single, isolated cell to other samples, analyzing the differences and similarities to better understand how the organisms originated and evolved - or even to discover entirely new species.

6 Aug 2021

Genome News and Research

Study unlocks genetic treasure chest for chronic kidney disease

Deep learning model can classify intracranial tumors using a single 3D MRI scan

New genomic and geological mapping tool may help track the deadliest of foodborne pathogens

Fine aerosols generated during talking, singing may play a major role in SARS-CoV-2 transmission

A new promising target for broad-spectrum therapeutics against coronaviruses

Study shows efficacy of gamma irradiation of SARS-CoV-2 vaccine candidate in mouse model

A multi-scale cryo-correlative platform to image SARS-CoV-2 in Vero cells

Researchers use prime editing to correct cystic fibrosis in cultured human stem cells

Study may provide a new therapeutic target for treatment of LUAD patients

Genetic testing in ambulatory cardiology clinics can benefit many patients

Computational study identifies key areas of the SARS-CoV-2 genome prone to mutation

New phylogenomic platform identifies increased recombination rates in SARS-CoV-2

New study describes SARS-CoV-2 ExoN enzyme that promotes antiviral resistance

New streamlined approach for high-coverage genome sequencing of single yeast cells

Study uncovers link between corticosteroid receptors and ciliary, neuroplasticity genes in the brain

Research reveals a microRNA network as putative mediators of myocardial reductive stress

Researchers create new model for studying earliest stages of retinoblastoma

Researchers identify genetic markers linked to COVID-19 severity and susceptibility

New method for producing pseudotyped virus particles bearing spike protein of SARS-CoV-2

PD1 gene deletions associated with worse prognoses of cutaneous T-cell lymphomas

The art of CRISPR: The power and promise of gene editing eBook

Lab Matters host Harriet Gould on building a more connected lab community

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

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