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Smoking and sex found to shape early cellular changes linked to bladder cancer

Bladder cancer is one of the most common cancers worldwide. Men are around four times more likely to develop it than women, and smoking is the main known environmental risk factor.

8 Oct 2025

New brain circuit discovery offers hope for chronic pain relief

Acute or short-lived pain, despite its bad reputation, is usually a lifesaver. It acts as a transient negative sensory experience that helps us avoid danger.

8 Oct 2025

Inappropriate triage prolongs time to pain medication in vaso-occlusive crisis

Most individuals living with sickle cell disease who presented to the emergency department with a pain crisis, known as vaso-occlusive crisis (VOC), were not triaged appropriately according to established national guidelines, reveals a study published today in Blood Advances.

8 Oct 2025

Study links extended breastfeeding to stronger infant immune health

Breastfeeding until at least six months helps babies to fight off infections and reduces chronic inflammation, according to a new study. And better understanding the way specific nutrients in breast milk impact the immune system will improve health outcomes for all infants including those not breastfed.

8 Oct 2025

Largest study of African American brain tissue reveals key Alzheimer gene activity

The prevalence of Alzheimer disease (AD) is approximately two times higher in African Americans (AA) compared to White/European-ancestry (EA) individuals living in the U.S.

8 Oct 2025

Ireland launches next phase of national precision oncology program

Today (8th October), Ireland's Minister for Further and Higher Education, Research, Innovation and Science, James Lawless TD, launched Phase 2 of the country's leading and largest ever cancer research program, Precision Oncology Ireland (POI).

8 Oct 2025

Japan's registry transforms outcomes for infants with biliary atresia

Biliary atresia (BA) is the leading cause of liver failure in infants, marked by progressive destruction of the bile ducts. Until the late 1950s, the disease was universally fatal, with no effective treatments. The development of the Kasai portoenterostomy brought new hope, but outcomes varied widely, and many patients still required liver transplantation (LTx).

8 Oct 2025

X-HiDE project advances toward earlier detection and precision treatment of inflammatory diseases

Facilitating earlier diagnosis and more precise treatment for patients with inflammatory diseases. This is the goal as the X-HiDE research project at örebro University in Sweden now enters its next phase, in collaboration with eleven companies and four other universities in Europe and the USA.

8 Oct 2025

New dual-target vaccine shows promise against typhoid and Salmonella

Researchers at the University of Maryland School of Medicine's Center for Vaccine Development and Global Health (CVD) have completed a successful Phase 1 clinical trial of a novel vaccine designed to protect against both typhoid fever and invasive non-typhoidal Salmonella--two major causes of illness and death among children in sub-Saharan Africa.

8 Oct 2025

Engineered CAR-NK cells show enhanced cancer killing and immune evasion

One of the newest weapons that scientists have developed against cancer is a type of engineered immune cell known as CAR-NK (natural killer) cells. Similar to CAR-T cells, these cells can be programmed to attack cancer cells.

8 Oct 2025

California’s nursing shortage is getting worse. Front-line workers blame management.

California, like much of the nation, is not producing enough nurses working at bedsides to meet the needs of an aging and diverse population, fueling a workforce crunch that risks endangering quality patient care.

8 Oct 2025

Empowering genomics research with cloud-based innovation

Discover how Discovery Life Sciences enhances genomics research with cloud-based platforms like DNAnexus.

From DNAnexus, Inc. 8 Oct 2025

Second World Congress to spotlight the science behind mitochondrial biology and microbiome research

The Second World Congress on Targeting Extracellular Vesicles (EVs) is scheduled for 15–16 October 2025 in Valencia, Spain. This landmark event, co-organized by the World Mitochondria Society and the International Society of Microbiota, will spotlight the rapidly evolving science where mitochondrial biology and microbiome research intersect via extracellular vesicles.

7 Oct 2025

New computer-driven method helps understand how membrane proteins work at the atomic level

Cellular membrane proteins play many important roles throughout the body, including transporting substances in and out of the cell, transmitting signals, speeding up reactions and helping neighboring cells stick together.

7 Oct 2025

Next-generation imaging promises sharper, deeper view of living tissues

A University of Arizona research team will receive nearly $2.7 million from the NIH's Common Fund Venture Program to advance next-generation imaging technologies that allow deeper, clearer views inside the body without the need for invasive procedures.

7 Oct 2025

GLP-1 receptor agonists linked to altered patterns on FDG PET-CT scans

The growing use of GLP-1 receptor agonists may affect the interpretation of oncological FDG PET-CT scans, new research presented today at the 38th Annual Congress of the European Association of Nuclear Medicine (EANM'25) has revealed.

7 Oct 2025

Exercise snacks may help improve heart and lung health in sedentary adults

Exercise snacks-intentional short bursts of physical activity-may be an effective way of boosting the cardiorespiratory fitness of physically inactive adults, finds a synthesis of the available research, published online in the British Journal of Sports Medicine.

7 Oct 2025

Tramadol found to offer limited relief for chronic pain while raising risk of serious side effects

The strong opioid painkiller, tramadol, is not that effective at easing chronic pain for which it's widely prescribed, finds a pooled data analysis of the available research, published online in BMJ Evidence Based Medicine.

7 Oct 2025

Scientists develop a high accuracy blood test to diagnose Chronic Fatigue Syndrome

Scientists at the University of East Anglia and Oxford Biodynamics have developed a high accuracy blood test to diagnose Chronic Fatigue Syndrome, also known as Myalgic Encephalomyelitis (ME/CFS).

7 Oct 2025

Whole genome sequencing may guide care for thousands of breast cancer patients

Whole genome sequencing offered to breast cancer patients is likely to identify unique genetic features that could either guide immediate treatment or help match patients to clinical trials for over 15,000 women a year, say scientists at the University of Cambridge.

7 Oct 2025