Brain News and Research

RSS

The human brain is the center of the human nervous system and is a highly complex organ. Enclosed in the cranium, it has the same general structure as the brains of other mammals, but is over three times as large as the brain of a typical mammal with an equivalent body size.

First step towards effective drug-addiction therapies

A novel chemical compound that blocks memory-related drug cravings has the potential to be the basis of new therapies to aid drug-addiction recovery efforts, UC Irvine neurobiologists have found.

26 Sep 2005

Scientists identifiy new type of pain-sensing neuron in rats

We all know that if you put your hand over an open flame it's very painful. What you may not know is that, for some people, just lying under a blanket is painful as well. They have neuropathic pain--annoying, chronic pain that comes from a diseased nerve cell rather than a specific stimulus. Feeling phantom pain in a missing limb is another, more famous, example.

26 Sep 2005

CytRx granted "Fast Track" designation for ALS drug

CytRx Corporation today announced that the U.S. Food and Drug Administration (FDA) has granted "Fast Track" designation for the company's leading drug candidate arimoclomol for the treatment of amyotrophic lateral sclerosis (ALS or Lou Gehrig's disease).

26 Sep 2005

Tests of cognitive function are the best way so far to predict whether healthy elderly people will develop Alzheimer's

Although Alzheimer's disease begins long before symptoms appear, early diagnosis of Alzheimer's has so far been elusive. And given that there is no cure for the disease, benefits of early detection remain questionable.

26 Sep 2005

Extreme gene pin-pointed

One teenager likes to snowboard off a cliff. Another prefers to read a book and wouldn't think of trading places. Why these differences exist is a mystery, but for the first time researchers have identified a possible genetic explanation behind risk-seeking behavior.

26 Sep 2005

Mutations in receptor tyrosine kinases provide potential for highly-targeted cancer therapies

Scientists from J. Craig Venter Institute, Ludwig Institute for Cancer Research, and The Johns Hopkins University School of Medicine identified three novel mutations in two receptor tyrosine kinases in glioblastoma tumors using high throughput sequencing.

26 Sep 2005

Aquaporin-4 is the first specific molecule to be defined as a target for the autoimmune response in any form of MS

Researchers have identified a molecular suspect in a disorder similar to multiple sclerosis (MS) that attacks the optic nerve and spinal cord, according to a report presented at the 130th annual meeting of the American Neurological Association in San Diego. The protein, called aquaporin-4, is a channel protein that allows water to move in and out of cells.

26 Sep 2005

Researchers have uncovered a significant contributing factor to interferon resistance of malignant melanoma cells

The finding represents a step forward in understanding the molecular events that govern the growth of this type of cancer and the changes in gene expression and cellular signaling that underlie resistance to established therapies.

26 Sep 2005

Scientists reverse memory loss in mice with Alzheimer's

In mice, that had been genetically engineered to develop Alzheimer's disease, scientists were able to reverse the rodents' memory loss by reducing the amount of an enzyme that is crucial for the development of Alzheimer's disease.

26 Sep 2005

Possible molecular origin of at least nine human diseases of nervous system degeneration

These neurodegenerative diseases, including Huntington's disease, share an abnormal deposit of proteins inside nerve cells. This deposition of protein results from a kind of genetic stutter within the cell's nucleus asking for multiple copies of the amino acid glutamine, a building block of protein structure.

26 Sep 2005

New approach to treating brain aneurysm combining the use of intracranial stents and coil embolization

A fender-bender may have saved Douglas Collins' life. A CT scan following the accident discovered Collins, 64, had a brain aneurysm, a weakness in the arterial wall that if ruptured could cause a stroke or death. It was not caused by the accident, but likely could have been a ticking time bomb present for years. The aneurysm was large and previously thought to require open surgery and a lengthy recovery.

26 Sep 2005

First-of-its kind atlas of the folds of the cerebral cortex

Neuroscientists at Washington University School of Medicine in St. Louis have assembled a first-of-its kind atlas of the folds of the cerebral cortex, the wrinkled surface layer of the brain credited with many of the higher cognitive functions that make us human.

26 Sep 2005

Two recent studies may help clinicians and researchers better predict and understand dementia of the Alzheimer's type

Both studies appear in the September issue of Neuropsychology, which is published by the American Psychological Association (APA). Psychologists focus on early detection in part because current medications are useful only when given very early in the course of the disease.

26 Sep 2005

Neurologix announces positive interim results of gene therapy clinical trial for patients with Parkinson's disease

Neurologix has announced positive interim results of its landmark gene therapy clinical trial for patients with Parkinson's disease. Neurologix's 12-patient, dose-escalating Phase I trial is the world's first study to use a viral vector (the non-pathogenic adeno-associated virus, or AAV) for the treatment of an adult neurological disease.

26 Sep 2005

New information about how the brain directs the body to make movements

A University of California - San Francisco (UCSF) study has revealed new information about how the brain directs the body to make movements. The key factor is "noise" in the brain's signaling, and it helps explain why all movement is not carried out with the same level of precision.

26 Sep 2005

PET brain scans of a brain chemical messenger system may prove sensitive enough to help plan brain surgery for epilepsy

When drugs fail to control epilepsy, brain surgery is often the only remaining therapeutic option. However, identifying the correct spot for surgery has traditionally required a separate preliminary -- and inherently risky -- surgical procedure.

26 Sep 2005

HIV-infected macrophages in the brain continuously travel to part of the brain Alzheimer's disease often damages

Bacteria-eating cells that generally fight infection may cause dementia in HIV patients, University of Florida and University of California at San Francisco researchers have found.

26 Sep 2005

Parkinson's dark period can be minimized or alleviated with the right kind of care

Some people call it "the dark time," the period between when a person is diagnosed with Parkinson's disease and when treatment with medication begins.

26 Sep 2005

Smaller prefrontal cortex is associated with early-onset drinking

Previous research has shown that alcohol-use disorders (AUDs) are associated with abnormalities of the prefrontal cortex, thalamus and the cerebellar hemispheres in adults.

26 Sep 2005

Definitive multiple sclerosis linkage screen

A cluster of genes on chromosome six is the only one that plays a significant role in multiple sclerosis (MS), according to the most complete genetic study to date in the disorder, presented at the 130th annual meeting of the American Neurological Association in San Diego.

22 Sep 2005

Brain News and Research

Further Reading

First step towards effective drug-addiction therapies

Scientists identifiy new type of pain-sensing neuron in rats

CytRx granted "Fast Track" designation for ALS drug

Tests of cognitive function are the best way so far to predict whether healthy elderly people will develop Alzheimer's

Extreme gene pin-pointed

Mutations in receptor tyrosine kinases provide potential for highly-targeted cancer therapies

Aquaporin-4 is the first specific molecule to be defined as a target for the autoimmune response in any form of MS

Researchers have uncovered a significant contributing factor to interferon resistance of malignant melanoma cells

Scientists reverse memory loss in mice with Alzheimer's

Possible molecular origin of at least nine human diseases of nervous system degeneration

New approach to treating brain aneurysm combining the use of intracranial stents and coil embolization

First-of-its kind atlas of the folds of the cerebral cortex

Two recent studies may help clinicians and researchers better predict and understand dementia of the Alzheimer's type

Neurologix announces positive interim results of gene therapy clinical trial for patients with Parkinson's disease

New information about how the brain directs the body to make movements

PET brain scans of a brain chemical messenger system may prove sensitive enough to help plan brain surgery for epilepsy

HIV-infected macrophages in the brain continuously travel to part of the brain Alzheimer's disease often damages

Parkinson's dark period can be minimized or alleviated with the right kind of care

Smaller prefrontal cortex is associated with early-onset drinking

Definitive multiple sclerosis linkage screen

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

Latest News