Autoimmune Disease News and Research

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Autoimmune Disease is a condition in which the body recognizes its own tissues as foreign and directs an immune response against them.

Enzyme appears to be a major driver of dangerous pregnancy complication

A new study by UT Southwestern scientists indicates that an enzyme called protein phosphatase 2 (PP2A) appears to be a major driver of preeclampsia, a dangerous pregnancy complication characterized by the development of high blood pressure and excess protein in the urine.

9 Sep 2021

New convection-enhanced MEDs could offer faster, more effective treatment for T1D patients

More than 40 million people worldwide are affected with type 1 diabetes (T1D) mellitus, an autoimmune disease in which insulin producing β-cells in the pancreas are destroyed by the immune system.

6 Sep 2021

Researchers identify biomarkers for rare, serious complication in children with COVID-19

The study focused on multisystem inflammatory syndrome in children (MIS-C), an inflammatory response involving multiple organs that can occur weeks after infection with SARS-CoV-2, the virus that causes COVID-19.

31 Aug 2021

New evidence provides strong support for the halt on prescribing hydroxychloroquine for COVID-19

In 2021, in the United States alone, there have been more than 560,000 prescriptions of hydroxychloroquine for the prevention, post-exposure and treatment of COVID-19.

31 Aug 2021

NIH begins clinical trial to assess extra COVID-19 vaccine dose in people with autoimmune disease

The National Institutes of Health has begun a clinical trial to assess the antibody response to an extra dose of an authorized or approved COVID-19 vaccine in people with autoimmune disease who did not respond to an original COVID-19 vaccine regimen.

27 Aug 2021

'Humanized' mouse model beats current approaches for finding the best organ donor

A "humanized" mouse model equipped with the immune system of a patient who needs an organ transplant beats current measures for identifying the best potential living donor, scientists report.

27 Aug 2021

Glycyrrhizic acid as a drug candidate for COVID-19

A new study presents the benefits of licorice, an age-old herbal remedy, to treat COVID-19 at all stages.

24 Aug 2021

New mouse model may help elucidate the pathogenic mechanisms behind Sjögren's syndrome

Sjögren's syndrome is an autoimmune disease that attacks the tear system in the eyes and salivary glands, leading to patients experiencing extremely dry eyes and mouth.

23 Aug 2021

Study in dogs may lead to better understanding of how gliomas affect the immune system

A new study reveals that high-grade gliomas, or brain tumors, in dogs contained more immune cells associated with suppressing immune response than low-grade gliomas.

20 Aug 2021

Study reveals mechanism behind male infertility caused by autoimmune disease

Investigators have found that the absence of autoimmune regulator (Aire) in mice results in fertility problems similar to those affecting men with autoimmune polyendocrine syndrome type I (APS-1).

19 Aug 2021

Sphingolipid profile could predict severity of heart disease in African American patients with lupus

A team of researchers at the Medical University of South Carolina report in Frontiers in Immunology that they have identified a type of fat known as a sphingolipid that could predict the severity of heart disease in African American patients with lupus.

16 Aug 2021

Small protein prevents immune system from destroying pancreatic cells in type 1 diabetes-prone mice

A new study has shown that treating type 1 diabetes-prone mice with the small protein MOTS-c prevented the immune system from destroying insulin-producing pancreatic cells, effectively preventing the onset of the autoimmune disease.

16 Aug 2021

Targeting a skin protein may reduce the severity of psoriasis, study reveals

Results from a Michigan Medicine study reveal that targeting a protein found in the skin may reduce the severity of psoriasis.

12 Aug 2021

Two-arm molecule can deplete cancer-protecting cells to promote immune responses against tumors

A two-arm molecule can effectively deplete cancer-protecting cells inside tumors, allowing the immune system to fight off tumors without becoming overactive. The finding, published online in Science Translational Medicine, could lead to new types of cancer immunotherapies.

11 Aug 2021

Breakthrough SARS-CoV-2 infections in patients with systemic rheumatic diseases

A recent study discusses the clinical characteristics and outcomes of patients with SARDs who were previously vaccinated against SARS-CoV-2.

11 Aug 2021

Defective process in the development of RBCs may trigger lupus

The autoimmune disease lupus may be triggered by a defective process in the development of red blood cells (RBCs), according to a study led by researchers at Weill Cornell Medicine.

11 Aug 2021

Impaired immune response to SARS-CoV-2 mRNA vaccination in immunocompromised patients

A new study describes how immunocompromised vaccine recipients may not always respond as expected to the COVID-19 vaccine.

27 Jul 2021

Maternal fecal transplant may help restore gut microbiota in newborns with diabetes risk

Newborns at risk for Type 1 diabetes because they were given antibiotics may have their gut microorganisms restored with a maternal fecal transplant, according to a Rutgers study.

20 Jul 2021

Targeting Piezo1 protein may be a new and ideal strategy to cure multiple sclerosis

In a new University of California, Irvine-led study, researchers found that a certain protein prevented regulatory T cells (Tregs) from effectively doing their job in controlling the damaging effects of inflammation in a model of multiple sclerosis (MS), a devastating autoimmune disease of the nervous system.

20 Jul 2021

IgA deficiency results in substantial intestinal inflammation, study reveals

While researchers have known for years that immunoglobulin A (IgA) is important for gut health, it has remained unclear exactly what role it plays in preventing infection and disease. But now, researchers from Japan have found that eliminating IgA disrupts the balance of the intestinal ecosystem, making it susceptible to disease.

20 Jul 2021

Autoimmune Disease News and Research

Further Reading

Enzyme appears to be a major driver of dangerous pregnancy complication

New convection-enhanced MEDs could offer faster, more effective treatment for T1D patients

Researchers identify biomarkers for rare, serious complication in children with COVID-19

New evidence provides strong support for the halt on prescribing hydroxychloroquine for COVID-19

NIH begins clinical trial to assess extra COVID-19 vaccine dose in people with autoimmune disease

'Humanized' mouse model beats current approaches for finding the best organ donor

Glycyrrhizic acid as a drug candidate for COVID-19

New mouse model may help elucidate the pathogenic mechanisms behind Sjögren's syndrome

Study in dogs may lead to better understanding of how gliomas affect the immune system

Study reveals mechanism behind male infertility caused by autoimmune disease

Sphingolipid profile could predict severity of heart disease in African American patients with lupus

Small protein prevents immune system from destroying pancreatic cells in type 1 diabetes-prone mice

Targeting a skin protein may reduce the severity of psoriasis, study reveals

Two-arm molecule can deplete cancer-protecting cells to promote immune responses against tumors

Breakthrough SARS-CoV-2 infections in patients with systemic rheumatic diseases

Defective process in the development of RBCs may trigger lupus

Impaired immune response to SARS-CoV-2 mRNA vaccination in immunocompromised patients

Maternal fecal transplant may help restore gut microbiota in newborns with diabetes risk

Targeting Piezo1 protein may be a new and ideal strategy to cure multiple sclerosis

IgA deficiency results in substantial intestinal inflammation, study reveals

Understanding the DNA Damage Response in Innate Immunity eBook

Evaluating new approaches for rare disease genomics

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Advancing Intracellular Delivery with LumiPore®

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