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The human brain is the center of the human nervous system and is a highly complex organ. Enclosed in the cranium, it has the same general structure as the brains of other mammals, but is over three times as large as the brain of a typical mammal with an equivalent body size.

Innovative HiTIP-seq method advances epigenetic research in pediatric brain tumors

Diffuse midline glioma (DMG) is a highly aggressive and fatal pediatric high-grade glioma that primarily affects critical regions of the central nervous system, such as the pons, thalamus, and spinal cord.

24 Sep 2024

Neurostimulation target identified for treating PTSD in veterans

A new study led by researchers at Brigham and Women's Hospital, a founding member of the Mass General Brigham healthcare system, suggests that using neurostimulation therapies on a specific brain network could treat post traumatic stress disorder (PTSD) in veterans.

24 Sep 2024

Internet searches predict ADHD medication prescriptions during COVID-19

In a groundbreaking study published in Brain Medicine (Genomic Press), UCI researchers have uncovered a striking correlation between internet searches for ADHD medications and actual prescription rates during the COVID-19 pandemic.

24 Sep 2024

Ultra-short heart rate variability recordings transform recovery tracking for TBI survivors

For the over 1 million Americans who survive severe traumatic brain injuries each year, the road to recovery is often long and challenging.

24 Sep 2024

Brain connectivity changes after psilocybin treatment in body dysmorphic disorder patients

Body dysmorphic disorder (BDD) is a debilitating mental illness characterized by an obsessive preoccupation with perceived flaws in one's physical appearance.

24 Sep 2024

Study links initial symptoms to long-term disability in multiple sclerosis

In a significant advance for multiple sclerosis (MS) research, a new study has uncovered a potential link between certain initial symptoms and long-term disability outcomes.

24 Sep 2024

Groundbreaking project seeks to illuminate the complexities of Parkinson's

Launching today, Landmark is a groundbreaking three-year research programme that aims to understand Parkinson’s in unprecedented detail. The project brings together Parkinson’s UK, Imperial College London, GSK, Novartis, Roche and UCB for the first time, and has been made possible by a founding gift of £4 million from the Gatsby charitable foundation.

24 Sep 2024

Neuroactive drugs show promising anti-glioblastoma effects in preclinical trials

Study explores the potential to repurpose neuroactive drugs, originally approved for neurological disorders, for the treatment of glioblastoma. Vortioxetine, an antidepressant, showed promising anti-glioblastoma activity, significantly reducing tumor size in preclinical trials.

24 Sep 2024

Simple intervention can prevent lifelong disability in premature babies

Giving women at risk of premature birth a simple magnesium sulphate infusion (or 'drip') can prevent their babies from developing cerebral palsy, a recent Cochrane review has confirmed. The drug itself costs approximately £5 (~$6.50) per dose in England, and requires hospital admission with experienced staff to administer the drug safely to the mother.

24 Sep 2024

Human challenge study reveals lasting cognitive decline after mild COVID-19

Researchers from the UK conducted the first human challenge study of SARS-CoV-2, revealing long-lasting cognitive deficits in unvaccinated participants infected with the virus, especially in memory and executive function.

23 Sep 2024

Study reveals key differences in how male and female brains process threats

A new study has uncovered significant differences in how male and female mice process threats, even as they exhibit similar behavioural responses.

23 Sep 2024

Researchers develop tools for objective pain measurement in the operating room

The degree to which a surgical patient's subconscious processing of pain, or "nociception," is properly managed by their anesthesiologist will directly affect the degree of post-operative drug side effects they'll experience and the need for further pain management they'll require.

23 Sep 2024

Breakthrough research reveals key role of melatonin receptor in REM sleep

A significant breakthrough in the understanding of sleep mechanism opens new promise for treating sleep disorders and associated neuropsychiatric conditions: Scientists have pinpointed the melatonin receptor MT1 as a crucial regulator of REM (Rapid Eye Movement) sleep.

23 Sep 2024

New defibrillation strategy could enhance survival rates in cardiac arrest

Joshua Lupton, M.D., has no memory of his own cardiac arrest in 2016. He only knows that first responders resuscitated his heart with a shock from a defibrillator, ultimately leading to his complete recovery and putting him among fewer than one in 10 people nationwide who survive cardiac arrest outside of a hospital.

23 Sep 2024

New recommendations for workplace chemical risk assessment published

The Permanent Senate Commission for the Investigation of Health Hazards of Chemical Compounds in the Work Area of the DFG has now published the English version of its latest research-based recommendations on the risk assessment of substances used at the workplace.

23 Sep 2024

Calcium channel blockers show potential to restore cerebral blood flow in Alzheimer's disease

Targeting calcium channels in pericytes may improve blood flow in Alzheimer's disease, addressing early vascular dysfunction linked to cognitive deficits.

23 Sep 2024

Liraglutide activates key brain circuits to trigger weight loss in obesity

Researchers uncover how liraglutide targets specific brain regions to suppress appetite and promote significant weight loss through GLP-1 receptor activation.

23 Sep 2024

Multi-modal AI systems for enhanced emotion detection and understanding

Using a fusion of traditional and novel technological methods, researchers are hoping to better quantify emotions to transform the face of the emotion quantification field.

23 Sep 2024

Brain scans reveal link between SSRI use and cognitive function

Researchers have found that SSRI (Selective Serotonin Reuptake Inhibitors) antidepressants have the potential to improve certain cognitive functions, such as verbal memory. They measured brain function in patients before and after taking the SSRI escitalopram and correlated this to a drop in the level of one of the serotonin receptors in the brain and to cognitive improvements during treatment.

22 Sep 2024