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Inaccurate data stalls pediatric equity initiatives

Leaders at three Michigan hospitals aiming to address equity issues for pediatric patients wanted to start with inspecting data key to identifying potential inequities.

3 Sep 2024

CDK4/6 inhibitors show promise for pediatric high-grade glioma treatment

CDK4/6 inhibitors, which are already FDA approved for the treatment of other forms of cancer, show early signs of promise in the treatment of a subtype of pediatric high-grade glioma, according to new research from Dana-Farber Cancer Institute and the Institute of Cancer Research in London.

3 Sep 2024

AI model enhances detection of immune-related adverse events in cancer patients

While immune checkpoint inhibitors (ICIs) can provide lifesaving treatment for patients with cancer, they have also been found to cause immune-related adverse events (irAEs) - side effects that can impact almost every organ in the body to varying degrees.

3 Sep 2024

Major trial to test multiple drugs for progressive supranuclear palsy

A clinical trial that will test three drugs concurrently, and could include more, represents new hope for patients with progressive supranuclear palsy (PSP), an incurable neurodegenerative disorder that usually kills within seven years after symptoms start.

3 Sep 2024

NSF AIRFoundry to advance RNA technology and nanoparticle design

In a typical foundry, raw materials like steel and copper are melted down and poured into molds to assume new shapes and functions.

3 Sep 2024

Long-term air pollution exposure and poor lifestyle choices increase risk of non-alcoholic fatty liver disease

Long-term exposure to air pollution and poor lifestyle choices are key contributors to non-alcoholic fatty liver disease (NAFLD), affecting global liver health.

3 Sep 2024

Beer and cider significantly raise gout risk for both sexes, but men are more affected

Study found that increased consumption of certain alcoholic beverages, particularly beer and spirits, is linked to a higher risk of gout in men, while women show varying associations depending on alcohol type and frequency.

3 Sep 2024

Funding boost accelerates development of promising rheumatoid arthritis treatment

Long term relief is within reach for people with the debilitating autoimmune disease, Rheumatoid Arthritis (RA), after an $11.5 million grant was awarded to a University of Queensland-led team.

2 Sep 2024

$FINEARTS-HF trial shows finerenone benefits for heart failure with preserved ejection fraction$

FINEARTS-HF trial shows finerenone benefits for heart failure with preserved ejection fraction

Finerenone reduced heart failure (HF) events and cardiovascular death in patients with HF and mildly reduced (HFmrEF) or preserved ejection fraction (HFpEF), according to late-breaking research presented in a Hot Line session today at ESC Congress 2024.

2 Sep 2024

Village doctor-led telemedicine reduces cardiovascular events in rural China

Telemedicine support to village doctors could hold the key to improving access to care for China's rural elderly at risk for developing potentially life-threatening complications resulting from untreated atrial fibrillation, according to late breaking research presented in a Hot Line Session at this year's ESC Congress 2024 in London, UK (30 Aug - 2 Sept).

2 Sep 2024

Complete revascularization proves effective for older STEMI patients in first 4 years

The benefits of complete revascularization over culprit-only coronary artery revascularisation were confirmed in older patients with ST-segment elevation myocardial infarction (STEMI) and multivessel disease over the first 4 years, according to late-breaking research presented in a Hot Line session today at ESC Congress 2024.

2 Sep 2024

Invasive strategy shows no benefit in cardiovascular death reduction for older NSTEMI patients

An invasive strategy vs. optimal medical therapy alone after a non-ST-elevation myocardial infarction (NSTEMI) in older adults did not affect the combined risk of cardiovascular death or MI, although non-fatal MIs and subsequent revascularisation procedures were reduced, according to late-breaking research presented in a Hot Line session today at ESC Congress 2024.

2 Sep 2024

Pooled analysis shows finerenone reduces all-cause mortality but not cardiovascular death

A pooled analysis of three large trials failed to demonstrate significant reductions in cardiovascular death with finerenone, but significantly lower all-cause mortality, cardiovascular events and kidney outcomes were observed, according to late-breaking research presented in a Hot Line session today at ESC Congress 2024.

2 Sep 2024

Study reveals key genetic markers for early onset bicuspid aortic valve complications

Genetic variants linked to a rare form of bicuspid aortic valve disease that affects young adults and can lead to dangerous and potentially life-threatening aortic complications have been identified by researchers at UTHealth Houston.

2 Sep 2024

Breakthrough in blood stem cell development offers hope for leukemia and bone marrow failure

Melbourne researchers have made a world first breakthrough into creating blood stem cells that closely resemble those in the human body. And the discovery could soon lead to personalized treatments for children with leukemia and bone marrow failure disorders.

2 Sep 2024

Study finds no added benefit of extensive ablation for persistent atrial fibrillation

In patients with persistent atrial fibrillation (AF), standard treatment with pulmonary vein isolation (PVI) ablation resulted in similar outcomes to more extensive ablation in other areas of the heart.

2 Sep 2024

Study reveals how neighboring synapses compete for plasticity resources

Nerve cells in the brain receive thousands of synaptic signals via their "antenna", the so-called dendritic branch.

2 Sep 2024

Fasting before cardiac catheterization not necessary, study finds

There was no difference in complications in patients who fasted or did not fast before cardiac catheterization procedures requiring conscious sedation, according to late-breaking research presented in a Hot Line session today at ESC Congress 2024.

2 Sep 2024

$Finerenone shows promise for heart failure with mildly reduced or preserved ejection fraction$

Finerenone shows promise for heart failure with mildly reduced or preserved ejection fraction

Finerenone reduced the composite of total first and recurrent heart failure (HF) events (hospitalizations for HF or urgent HF visits) and cardiovascular death in patients with HF and mildly reduced or preserved ejection fraction, according to an international clinical trial led by investigators from Brigham and Women's Hospital, a founding member of the Mass General Brigham healthcare system.

2 Sep 2024

Study identifies key predictors of severe mpox cases

The study uncovers factors influencing mpox severity and duration, emphasizing the role of viral load and specific clinical presentations in patient outcomes.

2 Sep 2024

Hospital News and Research

Inaccurate data stalls pediatric equity initiatives

CDK4/6 inhibitors show promise for pediatric high-grade glioma treatment

AI model enhances detection of immune-related adverse events in cancer patients

Major trial to test multiple drugs for progressive supranuclear palsy

NSF AIRFoundry to advance RNA technology and nanoparticle design

Long-term air pollution exposure and poor lifestyle choices increase risk of non-alcoholic fatty liver disease

Beer and cider significantly raise gout risk for both sexes, but men are more affected

Funding boost accelerates development of promising rheumatoid arthritis treatment

FINEARTS-HF trial shows finerenone benefits for heart failure with preserved ejection fraction

Village doctor-led telemedicine reduces cardiovascular events in rural China

Complete revascularization proves effective for older STEMI patients in first 4 years

Invasive strategy shows no benefit in cardiovascular death reduction for older NSTEMI patients

Pooled analysis shows finerenone reduces all-cause mortality but not cardiovascular death

Study reveals key genetic markers for early onset bicuspid aortic valve complications

Breakthrough in blood stem cell development offers hope for leukemia and bone marrow failure

Study finds no added benefit of extensive ablation for persistent atrial fibrillation

Study reveals how neighboring synapses compete for plasticity resources

Fasting before cardiac catheterization not necessary, study finds

Finerenone shows promise for heart failure with mildly reduced or preserved ejection fraction

Study identifies key predictors of severe mpox cases

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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