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UH pharmacology professor wins $900,000 grant to develop a dual-function nanodrug for cancer

Accelerating advancements in cancer prevention and cures, Wei Gao, assistant professor of pharmacology at the University of Houston College of Pharmacy, has received a $900,000 grant from the Cancer Prevention and Research Institute of Texas to develop stronger and more targeted anti-tumor therapy for pancreatic and lung cancer.

6 Jan 2026

Common blood signals explain why chronic diseases cluster as we age

This population-based study shows that shared and pattern-specific blood biomarkers reflect biological vulnerability underlying multimorbidity and the pace at which chronic diseases accumulate in older adults. Metabolic and systemic stress markers such as GDF15, HbA1c, cystatin C, and insulin consistently tracked higher disease burden and faster accumulation, with findings replicated across cohorts.

5 Jan 2026

Simple fruit granola intervention shows promising cardio-renal signals in CKD patients

A single-arm intervention study in Japanese adults with moderate chronic kidney disease found that replacing breakfast with fruit granola for two months lowered systolic blood pressure, reduced LDL-related lipid markers, and decreased a urinary marker of tubular injury. Renal function remained stable, bowel habits improved, and findings were exploratory due to the small, open-label design.

21 Dec 2025

Metformin fails to improve insulin resistance in type 1 diabetes

Metformin treatment in type 1 diabetes lowers insulin dosage but does not improve insulin resistance, highlighting its complex role in diabetes management.

26 Nov 2025

Deep learning AI model identifies first-of-its-kind biomarker of chronic stress

Using a deep learning AI model, researchers identified the first-of-its-kind biomarker of chronic stress detectable through routine imaging, according to research being presented next week at the annual meeting of the Radiological Society of North America.

25 Nov 2025

Inflammatory biomarkers offer new insights for precision medicine in ischemic stroke

Ischemic stroke, a leading cause of disability and mortality worldwide, is a complex cerebrovascular event with outcomes heavily influenced by the inflammatory response.

20 Nov 2025

Dash diet cuts diabetes complications by targeting blood pressure kidney health and inflammation

The DASH diet supports metabolic health in people with diabetes by improving blood pressure, renal function, lipids, and modest glycemic markers while reducing risks linked to vascular and inflammatory pathways. Its broad nutrient-driven mechanisms also benefit related conditions such as neuropathy, PCOS, and retinopathy, making it a versatile tool for cardiometabolic care.

16 Nov 2025

New approach to kidney transplant listing could improve outcomes and equity

The current kidney transplant waitlisting criterion is based on a single measurement of kidney function (estimated glomerular filtration rate [eGFR] ≤20 ml/min/1.73m2) and does not consider an individual's risk of progressing to kidney failure.

13 Nov 2025

Expanding the waitlisting criteria for kidney transplantation could improve patient outcomes

The current kidney transplant waitlistingcriterion is based on a single measurement of kidney function (estimated glomerular filtration rate [eGFR] ≤20 ml/min/1.73m2) and does not consider an individual’s risk of progressing to kidney failure.

10 Nov 2025

SGLT2 inhibitors show consistent cardio-renal protection in 70,000 patients

In late-breaking presentations at the American Society of Nephrology Kidney Week meeting and simultaneously published in two companion papers in JAMA, the findings are based on data from over 70,000 participants across 10 major randomised controlled trials. The meta-analyses were conducted by the SGLT2 Inhibitor Meta-analysis Cardio-Renal Trialists' Consortium (SMART-C), led by The George Institute for Global Health.

7 Nov 2025

Diabetes remission possible with GLP-1 drugs, Italian study confirms

In a large real-world Italian cohort, GLP-1 receptor agonist therapy led to measurable rates of type 2 diabetes remission, depending on how remission was defined. The most pragmatic definition (Remission 3) was linked to improved glycemia, weight, and a lower risk of microvascular and cardiovascular events.

29 Oct 2025

AI-powered LifeClock forecasts diseases years before symptoms appear

Researchers have developed LifeClock, an AI-driven biological clock trained on over 24 million electronic health records to estimate biological age across the human lifespan. The model accurately predicts disease risk years in advance, revealing distinct developmental and aging processes.

28 Oct 2025

Researchers map the complex sugar chains attached to rat serum proteins

A comprehensive study mapped the dynamic glycosylation landscape of rat serum proteins, uncovering sex- and time-dependent variations with clear cell-type specificity.

24 Oct 2025

Categorizing the risk factors for portal vein thrombosis in liver cirrhosis

Portal vein thrombosis (PVT) is a critical complication in liver cirrhosis (LC), significantly worsening portal hypertension and accelerating the progression to decompensation.

30 Sep 2025

Researchers design factor IX variants for short- and long-term Hemophilia B management

After blood vessel damage, effective blood clotting is essential to halt bleeding. However, this process is inefficient in some individuals due to hereditary factors. Hemophilia B, for example, results from a deficiency in coagulation factor IX (FIX), which can lead to prolonged bleeding after injuries or surgery.

30 Sep 2025

High levels of albumin in the urine linked to increased risk of dementia

A study shows that people with higher levels of the protein albumin in their urine are at increased risk of developing dementia. The study, led by researchers at Karolinska Institutet, is published in the scientific journal Journal of Internal Medicine.

24 Sep 2025

Scientists use blood chemistry to predict disease years before it strikes

Researchers built the largest plasma metabolome-phenome atlas using 274,241 UK Biobank participants, linking over 73,000 metabolite-trait and 52,000 metabolite-disease associations. The study shows metabolic risk scores can predict diseases years before diagnosis, with strong accuracy for diabetes and kidney complications.

22 Sep 2025

Breakthrough in building functional synthetic kidneys using assembloids

A USC Stem Cell-led research team has achieved a major step forward in the effort to build mouse and human synthetic kidneys.

17 Sep 2025

New class of antihypertensive medications may have both kidney- and cardio-protective benefits

Adding the novel medication baxdrostat to standard care may help manage high blood pressure and delay the progression of kidney disease in people with chronic kidney disease and uncontrolled high blood pressure , according to preliminary research presented at the American Heart Association's Hypertension Scientific Sessions 2025.

8 Sep 2025

Small peptide produced by gut bacteria identified as key factor in kidney fibrosis

A molecule made by bacteria in the gut can hitch a ride to the kidneys, where it sets off a chain reaction of inflammation, scarring and fibrosis - a serious complication of diabetes and a leading cause of kidney failure - according to a new study from researchers at the University of Illinois Urbana-Champaign and Mie University in Japan.

25 Aug 2025