Bone Health News and Research

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Molecular switch in mice links energy burning and bone health

Scientists' discovery of a molecular "switch" that activates an energy‑burning pathway in mice has the potential to lead to new treatments for bone disease.

11 May 2026

Infant exposure to environmental chemicals linked to lower bone density

Infants exposed to certain environmental chemicals, including breast milk and everyday products such as personal care items, are more likely to have lower bone density in the first year of their lives, according to research presented at the 28th European Congress of Endocrinology in Prague.

11 May 2026

Suppressing TGF-β signaling reactivates dormant bone cells to treat osteoporosis

Osteoporosis, a common skeletal disorder, is marked by reduced bone mass and deterioration of bone microarchitecture, making bones more porous and prone to fractures.

8 May 2026

Blocking TGF-beta may enhance osteoporosis bone regeneration therapies

A recent mouse model based study suggests that blocking TGF-β may improve osteoporosis treatment by helping quiescent osteoblasts in inactive bone surfaces return to an active state.

7 May 2026

Baylor researchers develop SAMENT method to map metastatic tumor niches

Researchers at Baylor College of Medicine and collaborating institutions developed a method that reveals the cellular makeup of tissues that support metastatic cancer growth, which is the primary cause of death for most patients with solid tumors.

28 Apr 2026

Vitamin E intake linked to a key fertility hormone in women trying to conceive

A cross-sectional study of 97 women with infertility found that higher vitamin E intake was associated with lower prolactin levels and smaller hip circumference. Riboflavin and calcium intake were linked to higher muscle mass percentage, but the findings are association-based and need confirmation in longitudinal studies.

26 Apr 2026

Researchers uncover new mechanism linking metabolism, immunity, and skeletal health

Obesity alters bone health not only through increased body weight but also by reshaping the bone marrow environment.

25 Apr 2026

High-fat, low-carbohydrate diet may improve beta-cell function in patients with type 2 diabetes

People with type 2 diabetes on a high-fat, low-carbohydrate diet may have a better chance of reversing their diabetes than those on a low-fat diet, according to a small study published in the Journal of the Endocrine Society.

21 Apr 2026

Alzheimer's risk gene APOE4 impacts bone health in females

Scientists at the Buck Institute for Research on Aging, along with collaborators at UC San Francisco, have discovered that APOE4, the most common genetic risk factor for Alzheimer's disease, causes bone quality deficits specifically in female mice, through a mechanism that is invisible to standard imaging and can emerge as early as midlife.

13 Apr 2026

New obesity definition may delay treatment and complicate diagnosis

Redefining obesity based not only on body mass index (BMI) but on whether excess body fat is causing measurable health problems may complicate diagnosis and delay treatment, according to an Endocrine Society guideline communication published in The Journal of Clinical Endocrinology & Metabolism.

2 Apr 2026

$Heart health linked to higher fracture risk in postmenopausal women$

Heart health linked to higher fracture risk in postmenopausal women

Postmenopausal women face a high risk of bone fractures. Due to declines in estrogen levels, which can lead to an increased risk of osteoporosis, even a low-impact fall can result in a serious hip, back or wrist injury.

27 Mar 2026

Early-life PFAS exposure may hinder adolescent bone development

Early-life exposure to per- and polyfluoroalkyl substances (PFAS) may influence how children's bones develop during adolescence, according to new research published in the Journal of the Endocrine Society.

17 Mar 2026

Activating hypoxia signaling improves metabolism and bone health

Obesity is widely known for increasing the risk of diabetes and cardiovascular disease, but its damaging effects on the skeleton are often overlooked. Excess body fat can disrupt bone metabolism, weaken bone quality, and impair fracture repair.

17 Mar 2026

Father's nicotine use may increase diabetes risk for offspring

A mouse study found that a father's nicotine exposure can affect the offspring's ability to process sugar and may contribute to diabetes risk, according to new research published in the Journal of the Endocrine Society.

12 Mar 2026

Higher intake of ultra processed foods linked to weaker bones

From flavored yogurts to frozen pizzas, breakfast cereals and instant oats, ultra-processed foods are convenient, often cheaper items designed for a quick bite.

12 Mar 2026

Periodontal bacteria trigger bone density reduction via the gut

Periodontitis, a chronic inflammatory disease of the gums, affects hundreds of millions of people worldwide and is increasingly linked to systemic disorders beyond the oral cavity.

4 Mar 2026

Study shows weighted vests prevent metabolic slowdown during weight loss

It's encouraging news for people trying to lose weight safely, especially older adults who want to drop pounds without losing bone or muscle mass.

3 Mar 2026

Post-exercise milk helps protect bone density in adults over 60

The study highlights the role of milk and resistance training in improving bone health and physical performance among older adults through nutrition education.

17 Feb 2026

Long-term omeprazole use linked to mineral imbalance risks

A study conducted in Brazil by researchers at the Federal University of São Paulo (UNIFESP) and the ABC Medical School (FMABC) warns that the prolonged use of proton pump inhibitors (PPIs) can impair nutrient absorption.

9 Feb 2026

Skin-delivered estrogen improves bone health in amenorrhoa

Hormone replacement therapy applied via the skin is the best way of protecting bone density in women whose periods have stopped due to anorexia or intense exercise, according to new research from Imperial College London and Imperial College Healthcare NHS Trust.

6 Feb 2026