Alzheimer's Disease News and Research

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Alzheimer's disease (AD) is an irreversible, progressive brain disease that slowly destroys memory and thinking skills and, eventually, the ability to carry out the simplest tasks of daily living. In most people with AD, symptoms first appear after age 60. AD is the most common cause of dementia among older people, but it is not a normal part of aging. Dementia refers to a decline in cognitive function that interferes with daily life and activities. AD starts in a region of the brain that affects recent memory, then gradually spreads to other parts of the brain. Although treatment can slow the progression of AD and help manage its symptoms in some people, currently there is no cure for this devastating disease.

Air pollution exposure linked to faster progression of Alzheimer’s disease

Exposure to high concentrations of air pollution may worsen Alzheimer's disease (AD) by accelerating the buildup of toxic proteins in the brain and speeding up cognitive decline.

8 Sep 2025

Study could pave the way for simple blood test to diagnose Alzheimer's disease

In a landmark study of Hispanic and Latino adults, researchers at University of California San Diego School of Medicine have identified a link between self-reported cognitive decline and blood-based biomarkers, which could pave the way for a simple blood test to help diagnose Alzheimer's disease and related dementias.

8 Sep 2025

Blood-based biomarkers reveal barriers to diversity in Alzheimer’s disease trials

Some of the populations with the highest risk for Alzheimer's disease remain greatly underrepresented in clinical trials-and a new study helps explain why.

5 Sep 2025

Impaired spatial orientation found in older adults at risk for Alzheimer’s disease

Individuals with an increased risk for dementia due to Alzheimer's disease can have impaired spatial orientation skills.

3 Sep 2025

Genetic variant disrupts brain’s cleanup crew increasing Alzheimer’s risk

A Nature study published today and led by researchers at the University of South Florida's USF Health Byrd Alzheimer's Institute pinpoints how a genetic variant disrupts microglia - the brain's "cleanup crew" - increasing the risk of Alzheimer's disease.

3 Sep 2025

Epigenomic erosion linked to cognitive decline in Alzheimer’s patients

Most people recognize Alzheimer's from its devastating symptoms such as memory loss, while new drugs target pathological aspects of disease manifestations, such as plaques of amyloid proteins.

2 Sep 2025

New insights into early brain circuit breakdown in Alzheimer’s

One of the first parts of the brain affected by Alzheimer's disease is the entorhinal cortex - a region that plays a big role in memory, spatial navigation, and the brain's internal mapping system.

2 Sep 2025

Brain pulsations driving glymphatic function differ in narcolepsy patients and healthy individuals

A hormone produced by the brain, orexin, may play a central role in the functioning of the brain’s glymphatic system, which clears waste, according to a new study from the University of Oulu.

1 Sep 2025

Glutamate receptors found to drive pediatric brain tumor development

The most common type of brain tumor in children, pilocytic astrocytoma (PA), accounts for about 15% of all pediatric brain tumors.

1 Sep 2025

Exploring testosterone's influence on cardiovascular, metabolic, reproductive, and mental health

For decades, testosterone has been recognized as the primary driver of male reproductive development and secondary sex characteristics.

1 Sep 2025

KRISS develops ultra-sensitive platform to detect Alzheimer’s biomarkers in body fluids

The Korea Research Institute of Standards and Science (KRISS, President Lee Ho Seong) has developed a diagnostic platform that amplifies the unique optical signals of molecules by more than a hundred million times, enabling the precise detection and quantification of trace amounts of Alzheimer's disease biomarkers in body fluids.

1 Sep 2025

How plant compounds could target Alzheimer’s disease from multiple angles

This review highlights how dietary polyphenols modulate Alzheimer’s disease biology through antioxidant, anti-inflammatory, and multi-target mechanisms, supported by in-silico docking analyses. Despite promise, challenges in bioavailability and brain delivery remain key hurdles to clinical translation.

31 Aug 2025

Discovery of mitochondrial microprotein opens path to obesity and aging therapies

Like bees breathing life into gardens, providing pollen and making flowers blossom, little cellular machines called mitochondria breathe life into our bodies, buzzing with energy as they produce the fuel that powers each of our cells.

29 Aug 2025

Alzheimer’s research uncovers a new therapeutic pathway for the memory-robbing malady

The gut contains the largest collection of immune cells in the body. New research at the Buck Institute shows that some of those immune cells travel along the brain/gut axis in a mouse model of Alzheimer's disease (AD) providing a potential new therapeutic pathway for the memory-robbing malady.

29 Aug 2025

Hormone therapy type may influence postmenopausal cognitive health

The type of estradiol-based hormone therapy taken during and after menopause, such as patches or pills, may be associated with differences in memory performance, according to a study published on August 27, 2025, in Neurology, the medical journal of the American Academy of Neurology.

28 Aug 2025

Routine eye exams may help detect Alzheimer’s years before symptoms appear

Within the next few years, doctors may be able to spot signs of Alzheimer's disease and other dementias using routine eye exams well before symptoms appear, a new study suggests.

27 Aug 2025

Study offers guidance for communicating with loved ones living with dementia

One of the great challenges faced by families coping with Alzheimer's disease and other forms of dementia is learning how to communicate effectively with the person impacted by the disease while also upholding their personhood, or sense of personal value.

27 Aug 2025

Alzheimer's Disease News and Research

Further Reading

Air pollution exposure linked to faster progression of Alzheimer’s disease

Study could pave the way for simple blood test to diagnose Alzheimer's disease

Blood-based biomarkers reveal barriers to diversity in Alzheimer’s disease trials

Impaired spatial orientation found in older adults at risk for Alzheimer’s disease

Genetic variant disrupts brain’s cleanup crew increasing Alzheimer’s risk

Epigenomic erosion linked to cognitive decline in Alzheimer’s patients

New insights into early brain circuit breakdown in Alzheimer’s

Brain pulsations driving glymphatic function differ in narcolepsy patients and healthy individuals

Glutamate receptors found to drive pediatric brain tumor development

Exploring testosterone's influence on cardiovascular, metabolic, reproductive, and mental health

KRISS develops ultra-sensitive platform to detect Alzheimer’s biomarkers in body fluids

How plant compounds could target Alzheimer’s disease from multiple angles

Discovery of mitochondrial microprotein opens path to obesity and aging therapies

Alzheimer’s research uncovers a new therapeutic pathway for the memory-robbing malady

Hormone therapy type may influence postmenopausal cognitive health

Routine eye exams may help detect Alzheimer’s years before symptoms appear

Study offers guidance for communicating with loved ones living with dementia

New light-based therapy shows promise for improving cognitive function in Alzheimer’s

Having a sense of purpose linked to lower dementia risk

Research uncovers key role of the brain's blood flow dynamics in Alzheimer’s disease

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