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Lung tumors rewire immune cells in the bone marrow before they reach cancer sites

Lung tumors don't just evade the immune system. They reshape it at its source. Researchers from the Icahn School of Medicine at Mount Sinai and collaborators report in the September 10 online issue of Nature that tumors rewire immune cells in the bone marrow before they even reach the cancer, suggesting a new target to enhance the durability of current immunotherapy

10 Sep 2025

Kids with fluctuating gut microbiome show poorer growth

Malnutrition is a leading cause of death in children under age 5, and nearly 150 million children globally under this age have stunted growth from lack of nutrition.

9 Sep 2025

Fatty acids circulating in the blood predict bone mineral density from childhood to adolescence

A recent study by the University of Eastern Finland is the first to report that the fatty acid composition of blood and the enzyme activity associated with it predict the development of bone mineral density from childhood to adolescence.

9 Sep 2025

New feedback mechanism in the brain could open avenues for treating people with sleep disorders

As every bodybuilder knows, a deep, restful sleep boosts levels of growth hormone to build strong muscle and bone and burn fat.

9 Sep 2025

'Resistin like molecule gamma' punches holes into heart cells after myocardial infarction

Nina Kumowski, MD, of the Department of Radiology and Center for Systems Biology at Massachusetts General Hospital, is the lead author and Matthias Nahrendorf, MD, PhD of the Department of Radiology and Center for Systems Biology at MGH, is the senior author of a paper published in Science, "Resistin-like molecule γ attacks cardiomyocyte membranes and promotes ventricular tachycardia."

9 Sep 2025

Biodegradable scaffold with magnesium and glutamine accelerates bone regrowth

For most broken bones, bone cells regrow on their own while patients wear a cast or brace to keep the injury steady.

9 Sep 2025

Targeting the lysosome-iron-mitochondria axis for osteoporosis therapy

Osteoporosis is a common skeletal disorder characterized by excessive bone loss, leading to increased fragility and an increased risk of fractures.

5 Sep 2025

Breast cancer cells hijack iron-handling macrophages to promote bone metastasis and anemia

Breast cancers frequently spread to the bone, establishing tumors that are largely impervious to treatment and are associated with poor patient prognoses.

4 Sep 2025

New insights into pathogenic T cells offer hope for Crohn's disease treatment

The research group led by Drs. Mitsuru Arase, Mari Murakami, and Prof. Kiyoshi Takeda (Graduate School of Medicine/ Immunology Frontier Research Center at The University of Osaka) revealed that transcription factors RUNX2 and BHLHE40 play crucial roles in inducing T cells involved in Crohn's disease.

4 Sep 2025

PEPITEM shows promise in treating osteoporosis by enhancing bone health

Researchers from the University of Birmingham, U.K., have identified bioactive peptide sequences in PEPITEM molecule, and demonstrated the biological of activity of the full PEPITEM molecule in counteracting key changes caused by osteoporosis.

2 Sep 2025

Dormant tumor cells targeted to reduce breast cancer relapse

A first-of-its-kind, federally funded clinical trial has shown it's possible to identify breast cancer survivors who are at higher risk of their cancer coming back due to the presence of dormant cancer cells and to effectively treat these cells with repurposed, existing drugs.

2 Sep 2025

Nanostructures boost CRISPR delivery for genetic medicine

With the power to rewrite the genetic code underlying countless diseases, CRISPR holds immense promise to revolutionize medicine. But until scientists can deliver its gene-editing machinery safely and efficiently into relevant cells and tissues, that promise will remain out of reach.

2 Sep 2025

$Walking faster may protect your bones and prevent fractures$

Walking faster may protect your bones and prevent fractures

A UK Biobank study links walking pace to osteoporosis risk, revealing brisk walking may protect bones and reduce fracture likelihood, regardless of genetics.

2 Sep 2025

Can saliva and tears replace blood tests for vitamin D and glucose?

Tears and saliva may offer new ways to monitor blood glucose and vitamin D levels, suggesting less invasive methods for managing chronic health conditions.

2 Sep 2025

Exploring testosterone's influence on cardiovascular, metabolic, reproductive, and mental health

For decades, testosterone has been recognized as the primary driver of male reproductive development and secondary sex characteristics.

1 Sep 2025

Genomic clues uncover early origins of multiple myeloma

A new study maps out the timeline of DNA damage for multiple myeloma, the second most common blood cancer.

1 Sep 2025

$New hypothesis links internal fat biology to heart failure with preserved ejection fraction$

Bone News and Research

Lung tumors rewire immune cells in the bone marrow before they reach cancer sites

Kids with fluctuating gut microbiome show poorer growth

Fatty acids circulating in the blood predict bone mineral density from childhood to adolescence

New feedback mechanism in the brain could open avenues for treating people with sleep disorders

'Resistin like molecule gamma' punches holes into heart cells after myocardial infarction

Biodegradable scaffold with magnesium and glutamine accelerates bone regrowth

Targeting the lysosome-iron-mitochondria axis for osteoporosis therapy

Breast cancer cells hijack iron-handling macrophages to promote bone metastasis and anemia

New insights into pathogenic T cells offer hope for Crohn's disease treatment

PEPITEM shows promise in treating osteoporosis by enhancing bone health

Dormant tumor cells targeted to reduce breast cancer relapse

Nanostructures boost CRISPR delivery for genetic medicine

Walking faster may protect your bones and prevent fractures

Can saliva and tears replace blood tests for vitamin D and glucose?

Exploring testosterone's influence on cardiovascular, metabolic, reproductive, and mental health

Genomic clues uncover early origins of multiple myeloma

New hypothesis links internal fat biology to heart failure with preserved ejection fraction

Visualizing lipid transport inside living cells with fluorescence microscopy

Inherited DNA changes can cause hormone imbalance in women with polycystic ovary syndrome

New NIH-funded project aims to turn rare HIV cures into broadly applicable immunotherapy

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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