Nanoparticle News and Research

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In nanotechnology, a particle is defined as a small object that behaves as a whole unit in terms of its transport and properties. It is further classified according to size: in terms of diameter, fine particles cover a range between 100 and 2500 nanometers, while ultrafine particles, on the other hand, are sized between 1 and 100 nanometers.

Reduced neutralization against Omicron variant in fully immunized adolescents with BNT162b2 vaccine

Researchers compare the humoral immune response in adolescents and adults after being completely immunized with the Pfizer BNT162b2 vaccine.

28 Jan 2022

Drug combo delivered in a nanoparticle formulation extends the survival of mice with medulloblastoma

UNC Lineberger Comprehensive Cancer Center researchers have demonstrated that a novel combination of two drugs that act as targeted inhibitors, delivered in a nanoparticle formulation, extend the survival of mice with medulloblastoma.

27 Jan 2022

Researchers discover a potential new way to combat antibiotic resistance

Researchers from Monash University have discovered a potential new way to prevent antibiotic resistance and reduce antibiotic intake.

25 Jan 2022

Research shows depletion of extracellular vesicles weakens immune response towards SARS-CoV-2

Over the past several years, considerable effort has been made towards developing better diagnostic and prognostic tools. However, until now, the focus of research has mainly been on the virus itself or the immune response it triggers. To unify diagnostic and prognostic tools for COVID-19 analyses, researchers propose using extracellular vesicles (EVs) from serum liquid biopsies.

24 Jan 2022

Researchers are in the race to beat Omicron

David Veesler and his lab members aren't getting much sleep these days. In the final weeks of 2021, he and his team worked around the clock to post four coronavirus papers on the preprint server bioRxiv.

24 Jan 2022

Nano-bubbles containing ACE2 protein can block infection from broad strains of SARS-CoV-2

Scientists at Northwestern Medicine and The University of Texas MD Anderson Cancer Center have identified natural nano-bubbles containing the ACE2 protein (evACE2) in the blood of COVID-19 patients and discovered these nano-sized particles can block infection from broad strains of SARS-CoV-2 virus in preclinical studies.

21 Jan 2022

Natural extracellular vesicles containing ACE2 protein could fight new SARS-CoV-2 variants

Scientists at The University of Texas MD Anderson Cancer Center and Northwestern Medicine have identified natural extracellular vesicles containing the ACE2 protein (evACE2) in the blood of COVID-19 patients that can block infection from broad strains of SARS-CoV-2 virus in preclinical studies. The study was published today in Nature Communications.

20 Jan 2022

Researchers develop nanotherapeutic drug to prevent cancer from spreading to the liver

Physician researchers from UT Southwestern Medical Center have developed an innovative nanotherapeutic drug that prevents cancer from spreading to the liver in mice.

19 Jan 2022

The latest advancements in polymer-based nanotechnology approaches used to fight against SARS-CoV-2

A recent review discusses the engineering versatility of polymeric nanoparticles - making a good therapeutic alternative against coronavirus diseases.

19 Jan 2022

Subcutaneous nanotherapy can make immunomodulation more effective in people with type 1 diabetes

Individuals living with type 1 diabetes must carefully follow prescribed insulin regimens every day, receiving injections of the hormone via syringe, insulin pump or some other device. And without viable long-term treatments, this course of treatment is a lifelong sentence.

18 Jan 2022

Study: Nearly 30% of people with blinding retinal disease can safely stop eye injection therapy

In a preliminary study of 106 people with "wet" age-related macular degeneration, Johns Hopkins Medicine researchers report that as many as a third of those with the blinding retinal disease may someday be able to safely stop eye injection therapy without further vision loss.

18 Jan 2022

Applications of bioconjugated nanomaterials in SARS-CoV-2 diagnostics

In this study, the researchers not only elucidate the recent bioconjugated nanomaterials for targeted diagnosis of SARS-CoV-2, but they also provide the rationale behind these developments by discussing the mechanisms and approaches.

18 Jan 2022

New method may help make immunomodulation more effective in individuals with Type 1 diabetes

Individuals living with Type 1 diabetes must carefully follow prescribed insulin regimens every day, receiving injections of the hormone via syringe, insulin pump or some other device. And without viable long-term treatments, this course of treatment is a lifelong sentence.

17 Jan 2022

Genome editing in vascular endothelial cells made possible with a powerful new delivery system

Northwestern Medicine scientists developed a unique nanoparticle to deliver genome editing technology, including CRISPR/Cas9, to endothelial cells, which line blood vessel walls.

16 Jan 2022

The impact of Comirnaty vaccination on the levels of PEG specific antibodies

Researchers observe an increase in PEG antibodies following vaccination with the SARS-CoV-2 mRNA lipid nanoparticle vaccine.

12 Jan 2022

Comparing the Moderna and Pfizer-Biontech vaccines against SARS-CoV-2 infection

A new study used target trial emulation design for comparison of both the vaccines in the VA healthcare system against the risk of infection, hospitalization, and death from COVID-19.

12 Jan 2022

New technique could allow more diseases to be safely treated by nanomedicine

Researchers at Penn Medicine have discovered a new, more effective method of preventing the body's own proteins from treating nanomedicines like foreign invaders, by covering the nanoparticles with a coating to suppress the immune response that dampens the therapy's effectiveness.

11 Jan 2022

Slight pH adjustment may turn a metabolic inhibiting drug into promising COVID-19 treatment

Mechanical engineering and materials science professor David Needham has shown that a slight increase in solution pH might be all it takes to turn a metabolic inhibiting drug, traditionally used to treat gut parasites, into a promising prophylactic/preventative nasal spray and early treatment throat spray for COVID-19.

7 Jan 2022

Curia unveils comprehensive mRNA solution

Curia, formerly AMRI, a leading contract research, development and manufacturing organization, today unveiled its messenger RNA solution, which includes discovery, process development and mRNA drug substance production, through large-scale lipid manufacturing, lipid nanoparticle formulation and development for full-scale sterile fill-finish services.

From Curia Global, Inc. 7 Jan 2022

From laboratory to clinic - Nanotechnology-enabled mRNA COVID-19 vaccines

In a recently published article in the journal Nano-Micro Letters, scientists have provided an in-depth review on the application and benefits of nanotechnology in the development of coronavirus disease 2019 (COVID-19) vaccines.

7 Jan 2022

Nanoparticle News and Research

Further Reading

Reduced neutralization against Omicron variant in fully immunized adolescents with BNT162b2 vaccine

Drug combo delivered in a nanoparticle formulation extends the survival of mice with medulloblastoma

Researchers discover a potential new way to combat antibiotic resistance

Research shows depletion of extracellular vesicles weakens immune response towards SARS-CoV-2

Researchers are in the race to beat Omicron

Nano-bubbles containing ACE2 protein can block infection from broad strains of SARS-CoV-2

Natural extracellular vesicles containing ACE2 protein could fight new SARS-CoV-2 variants

Researchers develop nanotherapeutic drug to prevent cancer from spreading to the liver

The latest advancements in polymer-based nanotechnology approaches used to fight against SARS-CoV-2

Subcutaneous nanotherapy can make immunomodulation more effective in people with type 1 diabetes

Study: Nearly 30% of people with blinding retinal disease can safely stop eye injection therapy

Applications of bioconjugated nanomaterials in SARS-CoV-2 diagnostics

New method may help make immunomodulation more effective in individuals with Type 1 diabetes

Genome editing in vascular endothelial cells made possible with a powerful new delivery system

The impact of Comirnaty vaccination on the levels of PEG specific antibodies

Comparing the Moderna and Pfizer-Biontech vaccines against SARS-CoV-2 infection

New technique could allow more diseases to be safely treated by nanomedicine

Slight pH adjustment may turn a metabolic inhibiting drug into promising COVID-19 treatment

Curia unveils comprehensive mRNA solution

From laboratory to clinic - Nanotechnology-enabled mRNA COVID-19 vaccines

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