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Hybrid cognitive behavioral therapy shows lasting benefits for pediatric anxiety and OCD

Jacqueline Sperling, PhD, a clinical psychologist and assistant professor of Psychology at Harvard Medical School, and co-program director of the McLean Anxiety Mastery Program, led a study investigating the sustainability of outcomes from an intensive group and family-based outpatient cognitive behavioral treatment (CBT) program, that included a hybrid of in-person and virtual treatment sessions for children and adolescents with anxiety disorders and/or obsessive-compulsive disorder (OCD).

23 Aug 2024

Innovations in biomarker detection and personalized medicine for prostate cancer

In a recent comprehensive review published in Cyborg Bionic Systems, researchers led by Keyi Li from the General Hospital of Northern Theater Command in Shenyang, along with international collaborators, detail significant advances in the identification and application of biomarkers for prostate cancer (PCa).

23 Aug 2024

Advances in sequencing uncover rare genetic variants in colorectal cancer

Colorectal cancer (CRC) presents a significant health challenge, especially with rare genetic variations complicating treatment.

23 Aug 2024

New AI-driven platform enhances lung cancer tissue analysis

A team of researchers from the University of Cologne's Faculty of Medicine and University Hospital Cologne, led by Dr Yuri Tolkach and Professor Dr Reinhard Büttner, has created a digital pathology platform based on artificial intelligence.

23 Aug 2024

New treatment for rectal cancer offers hope in avoiding surgery

A new treatment for locally advanced rectal cancer shows favorable results in that surgery can sometimes be avoided completely.

23 Aug 2024

Disability rights activist pushes government to let him participate in society

Garret Frey refuses to be sidelined. Frey has been paralyzed from the neck down for more than 37 of his 42 years. He has spent decades rejecting the government's excuses when he and others with disabilities are denied the support they need to live in their own homes and to participate in society.

23 Aug 2024

Olaparib effective against BRCA2-mutated prostate cancer

The anti-cancer drug olaparib may be effective in treating biochemically recurrent prostate cancer without accompanying hormone therapy for men who have mutations in genes such as BRCA2, according to results of a phase II clinical trial of 51 patients conducted at the Johns Hopkins Kimmel Cancer Center and three other sites.

23 Aug 2024

The impact of stem cells on the epigenetic clock

How old are you, really? Your chronological age is the number of years you have been alive. Your biological age is how old your cells are which scientists believe may better assess one's age-related health and disease risk. People biologically age at different rates, depending on genetic and environmental factors, so that a person's chronological age does not necessarily match their biological age. In recent years, direct-to-consumer biological age tests have become increasingly accessible and popular as interest has increased in this nascent science.

23 Aug 2024

FDA-approved drug could revolutionize organ transplantation

Researchers at the Wyss Institute for Biologically Inspired Engineering at Harvard University report that they were able to successfully put tadpoles of Xenopus laevis frogs into a hibernation-like torpor state using donepezil (DNP), a drug approved by the FDA to treat Alzheimer's. The team had previously used another drug, SNC80, to achieve similar results in tadpoles and enhance the survival of whole mammalian hearts for transplants, but SNC80 is not approved for clinical use in humans because it can cause seizures. By contrast, DNP is already being used in the clinic, meaning it potentially could be rapidly repurposed for use in emergency situations to prevent irreversible organ injury while a person is being transported to a hospital.

23 Aug 2024

$1.35 million grant to enhance safety and wellbeing in long-term care facilities

Researchers from the University of Colorado College of Nursing and CU School of Medicine on the Anschutz Medical Campus were awarded a $1.35 million grant from the Agency for Healthcare Research and Quality (AHRQ) to design and implement technologies that improve resident safety and employee wellbeing at long-term care facilities.

22 Aug 2024

$5 million grant to address combat wound infections in Ukraine

Faculty members in the Department of Emergency Medicine at the University of Colorado School of Medicine have been awarded $5 million by the U.S. Department of Defense to work with partners in Ukraine on clinical and logistical challenges associated with modern large-scale combat operations and prolonged casualty care.

22 Aug 2024

New insights into macrophages' role in MASH and liver fibrosis

Formerly known as nonalcoholic steatohepatitis, metabolic dysfunction-associated steatohepatitis (MASH) is an inflammatory disease characterized by liver scarring or fibrosis that progressively impairs liver function.

22 Aug 2024

Long-term low-dose cannabis reverses brain aging in mice

A low-dose long-term administration of cannabis can not only reverse aging processes in the brain, but also has an anti-aging effect.

22 Aug 2024

New research challenges belief that weight loss drugs only reduce appetite

A study carried out in St Vincent's University Hospital (SVUH) Dublin challenges the belief that weight loss medications such as Ozempic, Wegovy or Monjaro work just by promoting satiety and making you eat less.

22 Aug 2024

Study links fine particulate matter exposure to increased risk of gestational diabetes

Researchers assesses the relationship between exposure to fine particulate matter and the risk of gestational diabetes mellitus.

22 Aug 2024

The lingering mental health effects of severe COVID-19

A new study that examined health data on 18 million people reveals a higher incidence of mental illnesses for up to a year following severe COVID-19 in unvaccinated people. Vaccination appeared to mitigate the adverse effects of COVID-19 on mental illnesses. The University of Bristol-led study, published in JAMA Psychiatry on August 21st, 2024, investigated associations of COVID-19 with mental illnesses according to time since diagnosis and vaccination status.

22 Aug 2024

Exploring the impact of xylazine on wound care needs

The animal tranquilizer xylazine is increasingly found in the illicit opioid supply nationwide, leading to severe wounds among people who use drugs. New research led by a University of Pittsburgh physician-scientist and published in Drug and Alcohol Dependence seeks to understand the wound care experiences of this population.

22 Aug 2024

The surprising role of RNA in immune interactions

In a groundbreaking exploration of cell surface biology, Ryan Flynn has uncovered a surprising role for RNA outside the confines of the cell. Flynn's research, which focuses on the biology of cell surface RNA, led to the discovery that certain RNAs are chemically linked to glycans - complex carbohydrate polymers found on the cell surface.

22 Aug 2024

High dose psilocybin shows similar antidepressant effects to escitalopram

High doses of psilocybin - the active ingredient in magic mushrooms - appears to have a similar effect on depressive symptoms as the selective serotonin reuptake inhibitor (SSRI) drug escitalopram, suggests a systematic review and meta-analysis published in The BMJ today.

21 Aug 2024

Seizures detected at low levels of central thalamus stimulation in mice study

The idea of electrically stimulating a brain region called the central thalamus has gained traction among researchers and clinicians because it can help arouse subjects from unconscious states induced by traumatic brain injury or anesthesia, and can boost cognition and performance in awake animals.

21 Aug 2024