Alzheimer's Disease News and Research

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Alzheimer's disease (AD) is an irreversible, progressive brain disease that slowly destroys memory and thinking skills and, eventually, the ability to carry out the simplest tasks of daily living. In most people with AD, symptoms first appear after age 60. AD is the most common cause of dementia among older people, but it is not a normal part of aging. Dementia refers to a decline in cognitive function that interferes with daily life and activities. AD starts in a region of the brain that affects recent memory, then gradually spreads to other parts of the brain. Although treatment can slow the progression of AD and help manage its symptoms in some people, currently there is no cure for this devastating disease.

New monoclonal antibodies may provide blueprint for effective Alzheimer's disease treatments

Scientists at NYU Langone Medical Center's Center for Cognitive Neurology have evidence that monoclonal antibodies they developed may provide the blueprint for effective treatments for Alzheimer's disease and other neurodegenerative diseases, such as Parkinson's disease.

21 Jul 2015

C2N-8E12 (ABBV-8E12) gets orphan drug designation from FDA for PSP treatment

C2N Diagnostics and AbbVie today announced that the U.S. Food and Drug Administration has granted their investigational recombinant humanized anti-tau antibody, C2N-8E12 (ABBV-8E12), an orphan drug designation for the treatment of progressive supranuclear palsy (PSP).

17 Jul 2015

Type 2 diabetes patients with specific genetic markers at higher risk of developing Alzheimer's disease

Certain patients with type 2 diabetes (T2D) may have specific genetic risk factors that put them at higher risk for developing Alzheimer's disease (AD), according to a study conducted at the Icahn School of Medicine at Mount Sinai and published recently in Molecular Aspects of Medicine.

17 Jul 2015

Neuroscientists interpret code the brain uses to make noisy neuronal circuits

By analyzing the signals of individual neurons in animals undergoing behavioral tests, neuroscientists at Rice University, Baylor College of Medicine, the University of Geneva and the University of Rochester have deciphered the code the brain uses to make the most of its inherently "noisy" neuronal circuits.

17 Jul 2015

Having high blood pressure in midlife can affect cognition many years later

Having high blood pressure in your 50's may impact your ability to keep track or plan ahead in your 80's. This study reports a connection between high blood pressure at a younger age can affect cognition many years later. It currently appears in the Journal of Alzheimer's Disease.

17 Jul 2015

Transcranial magnetic stimulation holds promise for tinnitus patients

In the largest U.S. clinical trial of its kind funded by the Veterans Affairs Rehabilitation Research and Development Service, researchers at the VA Portland Medical Center and Oregon Health & Science University found that transcranial magnetic stimulation significantly improved tinnitus symptoms for more than half of study participants.

17 Jul 2015

Einstein-Montefiore researchers to present multiple findings at Alzheimer's Association International Conference

Investigators at Montefiore Health System and Albert Einstein College of Medicine of Yeshiva University will present multiple findings at the Alzheimer's Association International Conference, taking place July 18-23 in Washington, D.C. Research topics include risk factors for developing amnestic mild cognitive impairment (aMCI)—a condition characterized by memory problems, and is most often a precursor of Alzheimer's dementia.

16 Jul 2015

Scientists discover protein that plays significant role in development of fragile X syndrome

Scientists at VIB and KU Leuven have discovered that the protein APP plays a significant role in the development of fragile X syndrome (FXS) at young stages. They identified an unexpected biological pathway as a promising target to ameliorate deficits associated with FXS and autism. The results have recently been published in Neuron, one of the most influential journals in the field of neuroscience.

16 Jul 2015

New imaging technique could help with early detection of Alzheimer's disease

Various types of information can be ascertained by the way blood flows through the brain. When a region of the brain has been activated, blood flow increases and oxygenation rises. By observing variations in blood flow with the help of non-invasive imaging, it is possible to determine which regions are at work at a given point in time and how they work together.

16 Jul 2015

New research offers potential for early intervention to prevent neurodegenerative diseases

New research led by investigators at Beth Israel Deaconess Medical Center provides the first direct evidence linking traumatic brain injury to Alzheimer's disease and chronic traumatic encephalopathy (CTE) -- and offers the potential for early intervention to prevent the development of these debilitating neurodegenerative diseases.

16 Jul 2015

Potential diagnostic approach may detect individuals at increased risk for Alzheimer's disease

Individuals with amnestic mild cognitive impairment (aMCI) are at twice the risk of others in their age group of progressing to Alzheimer's disease. Although no conclusive test exists to predict who will develop Alzheimer's, new research from the Center for BrainHealth at The University of Texas at Dallas is attempting to identify a potential biomarker that could offer a more complete picture of who is most at risk.

16 Jul 2015

Research breakthrough opens door to a world of regenerative medicine for treating mitochondrial disease

A study led by Shoukhrat Mitalipov, Ph.D., and Hong Ma, M.D., Ph.D., at the Center for Embryonic Cell and Gene Therapy at Oregon Health & Science University and the Oregon National Primate Research Center has revealed the first critical step in developing novel gene and stem cell therapy treatments for patients with mitochondrial disease.

16 Jul 2015

Researchers identify gene that underlies thinking skills

An international team of researchers, including investigators from the University of Mississippi Medical Center, has identified a gene that underlies healthy information processing -- a first step on a complicated road to understand cognitive aging and age-related diseases, such as Alzheimer's disease.

16 Jul 2015

Older adults can boost brain function by raising their fitness level

New research conducted at the University of Kansas Medical Center indicates that older adults can improve brain function by raising their fitness level.

16 Jul 2015

Highlights from the most recent issue of Epilepsy Currents

The latest issue of Epilepsy Currents is now available featuring expert commentary on abstracts in basic science and clinical topics.

15 Jul 2015

Salk professor receives Allen Distinguished Investigator award to uncover biology of Alzheimer's disease

The Salk Institute today announced that Rusty Gage, Salk professor in the Laboratory of Genetics, has been selected as one of five recipients of the Paul G. Allen Family Foundation's Allen Distinguished Investigator (ADI) program and will be awarded $1.5 million to conduct his research. These researchers have projects aimed at uncovering the elusive biological foundations of Alzheimer's disease.

15 Jul 2015

Paul G. Allen Family Foundation announces ADI grants for Alzheimer's disease research

The Paul G. Allen Family Foundation announced today the award of Allen Distinguished Investigator (ADI) grants to five teams of researchers with projects that will open new and innovative avenues of research in Alzheimer's disease by uncovering its elusive biological roots.

14 Jul 2015

Alzheimer's disease may be 'at work' years ahead of actual symptoms, say IU researchers

The best-known genetic variant linked to Alzheimer's disease may be "at work" promoting deposits of plaque in the brain long before any symptoms of the disease can be measured on tests, according to a national research study led by Indiana University School of Medicine investigators.

14 Jul 2015

New study reveals how communication patterns sustain relationships between couples affected by AD

When a spouse is cognitively impaired, marital communication is impaired. As Alzheimer's disease (AD) progresses, language problems increase in frequency - such as searching for the right word, repeating the same word, asking the same question over and over, or substituting one word for another.

14 Jul 2015

Diabetes and high blood sugar impose negative effect on cognitive, decision-making skills

MINNEAPOLIS - In just two years, people with type 2 diabetes experienced negative changes in their ability to regulate blood flow in the brain, which was associated with lower scores on tests of cognition skills and their ability to perform their daily activities, according to a new study published in the July 8, 2015, online issue of Neurology, the medical journal of the American Academy of Neurology.

9 Jul 2015

Alzheimer's Disease News and Research

Further Reading

New monoclonal antibodies may provide blueprint for effective Alzheimer's disease treatments

C2N-8E12 (ABBV-8E12) gets orphan drug designation from FDA for PSP treatment

Type 2 diabetes patients with specific genetic markers at higher risk of developing Alzheimer's disease

Neuroscientists interpret code the brain uses to make noisy neuronal circuits

Having high blood pressure in midlife can affect cognition many years later

Transcranial magnetic stimulation holds promise for tinnitus patients

Einstein-Montefiore researchers to present multiple findings at Alzheimer's Association International Conference

Scientists discover protein that plays significant role in development of fragile X syndrome

New imaging technique could help with early detection of Alzheimer's disease

New research offers potential for early intervention to prevent neurodegenerative diseases

Potential diagnostic approach may detect individuals at increased risk for Alzheimer's disease

Research breakthrough opens door to a world of regenerative medicine for treating mitochondrial disease

Researchers identify gene that underlies thinking skills

Older adults can boost brain function by raising their fitness level

Highlights from the most recent issue of Epilepsy Currents

Salk professor receives Allen Distinguished Investigator award to uncover biology of Alzheimer's disease

Paul G. Allen Family Foundation announces ADI grants for Alzheimer's disease research

Alzheimer's disease may be 'at work' years ahead of actual symptoms, say IU researchers

New study reveals how communication patterns sustain relationships between couples affected by AD

Diabetes and high blood sugar impose negative effect on cognitive, decision-making skills

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