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Ribonucleic acid (RNA) is a biologically important type of molecule that consists of a long chain of nucleotide units. Each nucleotide consists of a nitrogenous base, a ribose sugar, and a phosphate.

Researchers find how common oral bacteria accelerates growth of colon cancer

Researchers at the Columbia University College of Dental Medicine have determined how F. nucleatum -- a common oral bacteria often implicated in tooth decay -- accelerates the growth of colon cancer. The study was published online in the journal EMBO Reports.

4 Mar 2019

Causes of disease including infant cancer can be revealed with new tool from Princeton University research team

Machine learning is being used to gain insight into the causes of hundreds of diseases, with Princeton University researchers discovering four specific genes that contribute to infant cancer.

4 Mar 2019

Nicotine could affect human embryonic development at the single-cell level

Nicotine induces widespread adverse effects on human embryonic development at the level of individual cells, researchers report February 28th in the journal Stem Cell Reports.

4 Mar 2019

Universal pan-filovirus T-cell vaccine could offer protection against Ebola and Marburg

Vaccines that induce protective T-cell responses could protect against members across the filovirus family, according to a study published February 28 in the open-access journal PLOS Pathogens by Tomáš Hanke of the University of Oxford, Bette Korber of the Los Alamos National Laboratory, and colleagues.

4 Mar 2019

New tool uncovers molecular causes of different diseases

Princeton University researchers are gaining new insights into the causes and characteristics of diseases by harnessing machine learning to analyze molecular patterns across hundreds of diseases simultaneously.

1 Mar 2019

Research reveals how metabolites can be used to inhibit epigenetic mechanisms and treat MS

Understanding and mitigating the role of epigenetics (environmental influences that trigger changes in gene expression) in disease development is a major goal of researchers.

28 Feb 2019

Researchers find how bats remain immune to various infections

An international research team led by Duke-NUS Medical School, Singapore, has identified molecular and genetic mechanisms that allow bats to stay healthy while hosting viruses that kill other animals, according to a new study published in the journal Nature Microbiology.

27 Feb 2019

Cancer genes’ mutational status influenced by their evolutionary age, regulatory functions

Researchers have provided new insight on why some genes that formed during the evolution of the earliest animals on earth are particularly impaired (or dysregulated) by specific mechanisms during cancer development.

26 Feb 2019

Novel mechanism behind DNA damage control uncovered

DNA damage is occurring in our cells all the time due to external agents, such as exposure to sun, or internal agents, like reactive oxygen species.

26 Feb 2019

Researchers outline targeted therapeutic strategy for triple-negative breast cancer

New findings put forth by the University of Maryland Fischell Department of Bioengineering and researchers from four other academic institutions outline a targeted therapeutic strategy to treat triple-negative breast cancer - a potential first for the particularly aggressive form of breast cancer.

26 Feb 2019

Researchers discover new and rare skeletal disease

Researchers at Karolinska Institutet in Sweden have discovered a new and rare skeletal disease. In a study published in the journal Nature Medicine they describe the molecular mechanism of the disease, in which small RNA molecules play a role that has never before been observed in a congenital human disease.

25 Feb 2019

Base Pair Biotechnologies to develop point-of-care tests for opioids in newborns

Base Pair Biotechnologies announced today the receipt of a Fast Track Small Business Innovation Research grant from the National Institute on Drug Abuse of the NIH

From Base Pair Biotechnologies, Inc. 25 Feb 2019

Study: Cancer stem-like cells are maintained by MTHFD2 mitochondrial metabolic enzyme

An increase in the incidence and mortality rate of cancer has been noted worldwide, especially for lung cancer.

22 Feb 2019

Why melanoma tumors in the brain may be worse?

Melanoma tumors that have spread to the brain are equipped to thwart immunotherapies and targeted therapies that succeed against tumors growing in other sites.

20 Feb 2019

Study shows therapeutic potential of VEGF-A mRNA for regenerative angiogenesis in humans

An international team of researchers from academia and the biopharma industry has published a Phase 1a/b study, showing the therapeutic potential of mRNA encoding for vascular endothelial growth factor A (VEGF-A) for regenerative angiogenesis in humans.

20 Feb 2019

New optimization method rapidly analyzes nanomedicines for cancer treatment

With their ability to treat a wide a variety of diseases, spherical nucleic acids (SNAs) are poised to revolutionize medicine. But before these digitally designed nanostructures can reach their full potential, researchers need to optimize their various components.

20 Feb 2019

Newly developed gene therapy helps decelerate aging process

Aging is a leading risk factor for a number of debilitating conditions, including heart disease, cancer and Alzheimer's disease, to name a few. This makes the need for anti-aging therapies all the more urgent. Now, Salk Institute researchers have developed a new gene therapy to help decelerate the aging process.

20 Feb 2019

Study reveals how helper T cells support memory cells to function optimally

The immune system's killer T cells are crucial in fighting viral infections. A fraction of them, called 'memory cells', live on once infection is controlled in order to fight re-infection by the same virus. They are of great interest as the basis of T cell-based vaccination and immunotherapies.

20 Feb 2019

Cervical microbiome may influence HPV infection more than previously thought

Infections with a Human Papillomavirus cause 99 percent of cervical cancer cases, and the disease's first sign is often the appearance of precancerous lesions on a woman's cervix. But bacteria may play an important role, too.

19 Feb 2019

Unique gene therapy approach paves new way to tackle rare, inherited diseases

Nonsense mutations are single-letter errors in the genetic code that prematurely halt the production of critical proteins. These unfinished proteins are unable to function normally, and nonsense mutations cause 10-15 percent of all inherited genetic diseases, including Duchenne muscular dystrophy, spinal muscular atrophy, cystic fibrosis and polycystic kidney disease.

19 Feb 2019

RNA News and Research

Further Reading

Researchers find how common oral bacteria accelerates growth of colon cancer

Causes of disease including infant cancer can be revealed with new tool from Princeton University research team

Nicotine could affect human embryonic development at the single-cell level

Universal pan-filovirus T-cell vaccine could offer protection against Ebola and Marburg

New tool uncovers molecular causes of different diseases

Research reveals how metabolites can be used to inhibit epigenetic mechanisms and treat MS

Researchers find how bats remain immune to various infections

Cancer genes’ mutational status influenced by their evolutionary age, regulatory functions

Novel mechanism behind DNA damage control uncovered

Researchers outline targeted therapeutic strategy for triple-negative breast cancer

Researchers discover new and rare skeletal disease

Base Pair Biotechnologies to develop point-of-care tests for opioids in newborns

Study: Cancer stem-like cells are maintained by MTHFD2 mitochondrial metabolic enzyme

Why melanoma tumors in the brain may be worse?

Study shows therapeutic potential of VEGF-A mRNA for regenerative angiogenesis in humans

New optimization method rapidly analyzes nanomedicines for cancer treatment

Newly developed gene therapy helps decelerate aging process

Study reveals how helper T cells support memory cells to function optimally

Cervical microbiome may influence HPV infection more than previously thought

Unique gene therapy approach paves new way to tackle rare, inherited diseases

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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