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Ribonucleic acid (RNA) is a biologically important type of molecule that consists of a long chain of nucleotide units. Each nucleotide consists of a nitrogenous base, a ribose sugar, and a phosphate.

FDA approves first injectable, complete regimen for HIV-1 infection in adults

The U.S. Food and Drug Administration today approved Cabenuva (cabotegravir and rilpivirine, injectable formulation) as a complete regimen for the treatment of human immunodeficiency virus type 1 (HIV-1) infection in adults to replace a current antiretroviral regimen in those who are virologically suppressed on a stable antiretroviral regimen with no history of treatment failure and with no known or suspected resistance to either cabotegravir or rilpivirine.

21 Jan 2021

AACR and MPM award three grants to support groundbreaking cancer research projects

Three grants for research that could transform cancer therapies have been awarded by the AACR-MPM Oncology Charitable Foundation Transformative Cancer Research Grants Program, an innovative partnership between the American Association for Cancer Research and the UBS Oncology Impact Fund managed by MPM Capital.

21 Jan 2021

New SARS-CoV-2 strain detected in Southern California, USA

By analyzing throat and nose swabs from patients in Southern California, researchers detected a new SARS-CoV-2 strain with mutations in the spike protein. This major finding may explain a surge in the number of cases in the region.

21 Jan 2021

Researchers immunoengineer nanobead system for circulating tumor cell detection

A team of researchers has immunoengineered a nanobead system for the isolation and detection of circulating tumor cells.

21 Jan 2021

Busting myths on airborne transmission of SARS-CoV-2

The rapid spread of COVID-19 caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has led to significant research on the mechanisms of how the virus spreads, which is usually by airborne transmission.

20 Jan 2021

COVID-19 has transformed the world of vaccines

Researchers at GlaxoSmithKline (GSK) in Italy and Belgium say the coronavirus disease 2019 (COVID-19) pandemic is transforming the world of vaccinology by accelerating vaccine development and the availability of powerful technologies.

20 Jan 2021

Ethacrynic acid, a diuretic drug with potential anti-SARS-CoV-2 activity

A study published recently in the journal Viruses has identified a potent diuretic ethacrynic acid as an efficient inhibitor of the main protease of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). This drug can be potentially repurposed to treat coronavirus disease 2019 (COVID-19).

20 Jan 2021

How does SARS-CoV-2 infect brain cells?

Researchers from the University of California San Francisco, Gladstone Institutes in the USA, and The Aga Khan University in Pakistan investigated if human neural cells can be infected by SARS-CoV-2.

20 Jan 2021

Gene editing shows potential to correct mutations causing inherited retinal degeneration

Gene editing therapies, including CRISPR-Cas systems, offer the potential to correct mutations causing inherited retinal degenerations, a leading cause of blindness.

20 Jan 2021

Researchers develop ultra-small nanomedicines to target intractable cancers

Ultra-small nanomedicines of approximately 18 nm were fabricated by dynamic ion-pairing between Y-shaped block copolymers and nucleic acid drugs, such as siRNA and antisense drugs.

19 Jan 2021

The structure dynamics of the SARS-CoV-2 genome in cells, cell lysates and virions

Now, a new preprint research paper posted to the bioRxiv server describes the structures observed during the lifecycle of the RNA virus in terms of both canonical and alternative structures, RNA-RNA interactions, and replication regulation.

19 Jan 2021

Carbon-based nanomaterials as potential COVID-19 treatments

An international team of researchers says that carbon-based nanomaterials (CBNs) could represent promising new approaches to treating coronavirus disease 2019 (COVID-19) pneumonia that is complicated by a secondary bacterial, viral or fungal infection.

19 Jan 2021

Gene-cutting system may play second role as a genetic dimmer switch

In a series of experiments with laboratory-cultured bacteria, Johns Hopkins scientists have found evidence that there is a second role for the widely used gene-cutting system CRISPR-Cas9 -- as a genetic dimmer switch for CRISPR-Cas9 genes.

19 Jan 2021

Viral genome sequencing of wastewater can be useful for tracking new SARS-CoV-2 variants

Viral genome sequencing of wastewater can detect new SARS-CoV-2 variants before they are detected by local clinical sequencing, according to a new study reported in mBio, an open-access journal of the American Society for Microbiology.

19 Jan 2021

Research finds new evidence about the mechanisms controlling skin repair and regeneration

As the air continues to dry and temperatures drop, the yearly battle against dry hands and skin has officially begun. New research from Northwestern University has found new evidence deep within the skin about the mechanisms controlling skin repair and renewal.

19 Jan 2021

New method could provide additional insight into brain tumors

A look at RNA tells us what our genes are telling our cells to do, and scientists say looking directly at the RNA of brain tumor cells appears to provide objective, efficient evidence to better classify a tumor and the most effective treatments.

19 Jan 2021

About 60 percent of SARS-CoV-2 cases in England tied to new variant by the end of December

One new SARS-CoV-2 variant of concern, called 202012/01, started to spread in England in late October. A new study published on the pre-print server medRxiv found that 60 percent of daily COVID-19 cases screened by the Alderley Park Lighthouse Labs were tied to 202012/01, also known as lineage B.1.1.7 or 20B/501Y.V1. This suggests a rapid spread of the new variant across the country.

18 Jan 2021

Research suggests seaweed used in traditional Chinese medicine could protect against COVID-19

Researchers in China have conducted a study showing that a carbohydrate found in the seaweed Ecklonia kurome blocks the activity of an enzyme that is essential for the replication of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent that causes coronavirus disease 2019 (COVID-19).

18 Jan 2021

SARS-CoV-2 RNA in blood serum could predict COVID-19 mortality

Researchers find that the presence of SARS-CoV-2's genetic material in the serum of positive patients could be a sturdy biomarker for predicting COVID-19-related mortality.

18 Jan 2021

New computational technique accurately differentiates between data from tumor cells and normal cells

In an effort to address a major challenge when analyzing large single-cell RNA-sequencing datasets, researchers from The University of Texas MD Anderson Cancer Center have developed a new computational technique to accurately differentiate between data from cancer cells and the variety of normal cells found within tumor samples.

18 Jan 2021

RNA News and Research

Further Reading

FDA approves first injectable, complete regimen for HIV-1 infection in adults

AACR and MPM award three grants to support groundbreaking cancer research projects

New SARS-CoV-2 strain detected in Southern California, USA

Researchers immunoengineer nanobead system for circulating tumor cell detection

Busting myths on airborne transmission of SARS-CoV-2

COVID-19 has transformed the world of vaccines

Ethacrynic acid, a diuretic drug with potential anti-SARS-CoV-2 activity

How does SARS-CoV-2 infect brain cells?

Gene editing shows potential to correct mutations causing inherited retinal degeneration

Researchers develop ultra-small nanomedicines to target intractable cancers

The structure dynamics of the SARS-CoV-2 genome in cells, cell lysates and virions

Carbon-based nanomaterials as potential COVID-19 treatments

Gene-cutting system may play second role as a genetic dimmer switch

Viral genome sequencing of wastewater can be useful for tracking new SARS-CoV-2 variants

Research finds new evidence about the mechanisms controlling skin repair and regeneration

New method could provide additional insight into brain tumors

About 60 percent of SARS-CoV-2 cases in England tied to new variant by the end of December

Research suggests seaweed used in traditional Chinese medicine could protect against COVID-19

SARS-CoV-2 RNA in blood serum could predict COVID-19 mortality

New computational technique accurately differentiates between data from tumor cells and normal cells

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