Antibody News and Research

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An antibody is a blood protein that is produced in response to and counteracts an antigen. Antibodies are produced in response to disease and help the body fight against the particular disease. In this way, antibodies help the body develop an immunity to disease.

Research highlights guselkumab's impact on Crohn's endoscopic healing

In a major advance for patients with Crohn's disease, a new study led by researchers at Mount Sinai Health System found that guselkumab, a medication with a mechanism of action that is new to inflammatory bowel disease (IBD) treatment, outperformed an established standard of care in promoting intestinal healing and symptom relief.

18 Jul 2025

Specially engineered antibody delivers RNA therapy to treatment-resistant tumors

A specially engineered antibody capable of delivering RNA therapies to hard-to-reach, treatment-resistant tumors significantly shrank tumor size and improved survival in animal models, according to a study published July 16 in Science Translational Medicine.

17 Jul 2025

New monoclonal antibody enhances immune response by selectively targeting Tregs

A new research paper was published in Volume 16 of Oncotarget on July 9, 2025, titled "A novel anti-human CD25 mAb with preferential reactivity to activated T regulatory cells depletes them from the tumor microenvironment."

17 Jul 2025

UNM researchers get $1 million grant to launch early clinical trial for Alzheimer’s vaccine

University of New Mexico researchers have received funding to launch an early-stage clinical trial of a vaccine engineered to clear pathological tau protein from the brains of patients suffering from Alzheimer's dementia.

15 Jul 2025

McMaster study identifies the most effective and safest treatments for chronic hives

A new international study led by researchers at McMaster University has identified the most effective and safest treatments for people suffering from chronic urticaria, more commonly known as chronic hives.

15 Jul 2025

New autoimmune target identified in pediatric idiopathic nephrotic syndrome

Idiopathic nephrotic syndrome (INS) is a serious kidney disease in children with no clear cause. In a recent study, researchers have identified a novel autoantibody targeting vinculin—a protein crucial for kidney cell structure—as a significant factor in INS.

14 Jul 2025

New nanobody-liposome combo stops lung cancer growth and delivers targeted chemotherapy

Researchers engineered a nanobody-conjugated liposome (A5-LNP-DOX) that targets CD155 and delivers doxorubicin directly to lung adenocarcinoma cells, dramatically suppressing tumor growth in preclinical models. This approach not only inhibited cancer cell migration and invasion but also showed strong potential for safer, more precise lung cancer therapy.

14 Jul 2025

Nasal antibody spray shields mice from pollen-triggered allergies and asthma

Intranasal delivery of a monoclonal IgG1 antibody targeting mugwort pollen protected mice from allergic rhinitis and asthma symptoms, without lowering systemic IgE levels. This localized, non-invasive approach dampened Th2 inflammation and preserved healthy airway tissue in sensitized mice.

14 Jul 2025

Early-career physician-scientists receive major support from Damon Runyon Cancer Research Foundation

The Damon Runyon Cancer Research Foundation has named five new Damon Runyon Clinical Investigators.

14 Jul 2025

New blood test predicts multiple sclerosis years before symptoms

A research team at the Medical University of Vienna has developed a blood test that allows the identification of individuals at risk for developing multiple sclerosis (MS) with a high degree of certainty years before the onset of symptoms.

14 Jul 2025

New immunotherapy targets leukemia at its root

Researchers at MUSC Hollings Cancer Center have identified a signaling loop involved in the growth and persistence of leukemia cells – and developed a novel immunotherapy that can disrupt that loop to boost immune function and improve survival.

14 Jul 2025

Engineered exosomal spheres enhance melanoma immunotherapy through improved tumor penetration

This new article publication from Acta Pharmaceutica Sinica B, discusses the use of engineered platelet-derived exosomal spheres for enhanced tumor penetration and extended circulation in melanoma immunotherapy.

12 Jul 2025

New microchip tracks antibody-virus interactions from a single drop of blood

A new microchip invented by Scripps Research scientists can reveal how a person's antibodies interact with viruses-using just a drop of blood.

12 Jul 2025

Teclistamab shows promising results in heavily pretreated multiple myeloma

Teclistamab-cqyv (Tecvayli) led to clinically meaningful responses in patients with heavily pretreated multiple myeloma who would have been ineligible for the MajesTEC-1 trial, and identified a novel factor independently associated with outcomes.

12 Jul 2025

Scientists identify key role of T-bet in flu memory B cells

At the surface, the immune response to a flu virus is simple. Some cells recognize the pathogen and send a signal to the immune system, and immune cells produce a potentially lifesaving antibody against the virus. Antigen in, antibody out.

11 Jul 2025

Monoclonal antibody delivered through the nose blocks hay fever in mice

Approximately 40% of the European population are allergic to pollen, and their symptoms cause an estimated loss of 100 million school- and workdays every year.

11 Jul 2025

Introducing the iQue® 5 HTS Platform: empowering scientists with unbeatable speed and flexibility for high throughput screening by cytometry

The life science group Sartorius launches the new iQue® 5 High-Throughput Screening (HTS) Cytometer, transforming workflows with next-level flexibility and comprehensive analysis at unbeatable speeds. Building on core iQue® strengths as the market leading solution for HTS applications, the iQue® 5 expands experimental range with up to 27 channels (25 color options) and flexible workflows in 96- and 384-well formats.

From Sartorius 11 Jul 2025

Vanderbilt and Parse Biosciences team up to develop antibody treatments for measles

Vanderbilt University Medical Center and Parse Biosciences, an innovator in single-cell sequencing, are collaborating on a new treatment to help unvaccinated measles victims, as the U.S. measles outbreak has now reached its highest case count in 30 years.

8 Jul 2025

Tiny nanobody shows big promise in fighting Nipah and Hendra viruses

Researchers have discovered a strategy to neutralize two highly lethal viruses for which there is currently no approved vaccine or cure.

8 Jul 2025

Innovative bispecific antibody targets LAG-3 to treat autoimmune diseases

Immune checkpoint pathways regulate T cell function and play pivotal roles in the treatment of both cancer and autoimmune diseases.

7 Jul 2025

Antibody News and Research

Further Reading

Research highlights guselkumab's impact on Crohn's endoscopic healing

Specially engineered antibody delivers RNA therapy to treatment-resistant tumors

New monoclonal antibody enhances immune response by selectively targeting Tregs

UNM researchers get $1 million grant to launch early clinical trial for Alzheimer’s vaccine

McMaster study identifies the most effective and safest treatments for chronic hives

New autoimmune target identified in pediatric idiopathic nephrotic syndrome

New nanobody-liposome combo stops lung cancer growth and delivers targeted chemotherapy

Nasal antibody spray shields mice from pollen-triggered allergies and asthma

Early-career physician-scientists receive major support from Damon Runyon Cancer Research Foundation

New blood test predicts multiple sclerosis years before symptoms

New immunotherapy targets leukemia at its root

Engineered exosomal spheres enhance melanoma immunotherapy through improved tumor penetration

New microchip tracks antibody-virus interactions from a single drop of blood

Teclistamab shows promising results in heavily pretreated multiple myeloma

Scientists identify key role of T-bet in flu memory B cells

Monoclonal antibody delivered through the nose blocks hay fever in mice

Introducing the iQue® 5 HTS Platform: empowering scientists with unbeatable speed and flexibility for high throughput screening by cytometry

Vanderbilt and Parse Biosciences team up to develop antibody treatments for measles

Tiny nanobody shows big promise in fighting Nipah and Hendra viruses

Innovative bispecific antibody targets LAG-3 to treat autoimmune diseases

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