Alzheimer's Disease News and Research

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Alzheimer's disease (AD) is an irreversible, progressive brain disease that slowly destroys memory and thinking skills and, eventually, the ability to carry out the simplest tasks of daily living. In most people with AD, symptoms first appear after age 60. AD is the most common cause of dementia among older people, but it is not a normal part of aging. Dementia refers to a decline in cognitive function that interferes with daily life and activities. AD starts in a region of the brain that affects recent memory, then gradually spreads to other parts of the brain. Although treatment can slow the progression of AD and help manage its symptoms in some people, currently there is no cure for this devastating disease.

Deleting enzyme favorably impacts behaviors associated with autistic behaviors

Fragile X syndrome (FXS) is a genetic disorder that causes obsessive-compulsive and repetitive behaviors, and other behaviors on the autistic spectrum, as well as cognitive deficits. It is the most common inherited cause of mental impairment and the most common cause of autism.

24 Jul 2014

New therapeutic interventions that target brain regions can prevent obesity

Unlocking the secrets to better treating the pernicious disorders of obesity and dementia reside in the brain, according to a paper from American University's Center for Behavioral Neuroscience.

24 Jul 2014

Compounds developed for cancer treatment show promise as potential oral therapy for Alzheimer's

Currently, no cure exists for Alzheimer's disease, the devastating neurological disease affecting more than 5 million Americans. But scientists are now reporting new progress on a set of compounds, initially developed for cancer treatment, that shows promise as a potential oral therapy for Alzheimer's. Their study appears in ACS' Journal of Medicinal Chemistry.

24 Jul 2014

Monitoring pulse regularly after stroke helps prevent next stroke

New research suggests that regularly monitoring your pulse after a stroke or the pulse of a loved one who has experienced a stroke may be a simple and effective first step in detecting irregular heartbeat, a major cause of having a second stroke.

24 Jul 2014

Study reveals novel epilepsy pathway linked to neurodegenerative diseases

A recent scientific discovery showed that mutations in prickle genes cause epilepsy, which in humans is a brain disorder characterized by repeated seizures over time. However, the mechanism responsible for generating prickle-associated seizures was unknown.

23 Jul 2014

Signs and symptoms of Lewy body dementia

"I watched my husband experience a decline in cognition followed by a period of what seemed like improved function only to plunge again into confusion with more frequent hallucinations," says one caregiver newly acquainted with Lewy body dementia (LBD).

22 Jul 2014

Study finds microglia increase neuronal firing and enhance brain cell survival after injury

A type of immune cell widely believed to exacerbate chronic adult brain diseases, such as Alzheimer's disease and multiple sclerosis (MS), can actually protect the brain from traumatic brain injury (TBI) and may slow the progression of neurodegenerative diseases, according to Cleveland Clinic research published today in the online journal Nature Communications.

22 Jul 2014

New discovery links two important hypotheses in Alzheimer's disease research

In Alzheimer's disease, accumulation of amyloid plaque in the brain is believed to play an important role in many characteristic disease symptoms, including memory loss and other mental state changes.

22 Jul 2014

Elevated ASM activity linked to Alzheimer's disease

Unclogging the body's protein disposal system may improve memory in patients with Alzheimer's disease (AD), according to a study from scientists at Kyungpook National University in Korea published in The Journal of Experimental Medicine.

22 Jul 2014

Brain network measures placebo effects in Parkinson's disease patients

Investigators at The Feinstein Institute for Medical Research have utilized a new image-based strategy to identify and measure placebo effects in randomized clinical trials for brain disorders. The findings are published in the August issue of The Journal of Clinical Investigation.

19 Jul 2014

Moxibustion and electroacupuncture alleviate neuronal cytoplasmic edema in AD

Aberrant Wnt signaling is possibly related to the pathological changes in Alzheimer's disease (AD). Axin and β-catenin protein is closely related to Wnt signaling.

18 Jul 2014

Structural change in periventricular white matter may show correlation with cognitive, sensory motor deficits by aging

Ventricular enlargement has been suggested as a structural biomarker for normal aging and progression of some illnesses, such as Alzheimer's disease.

17 Jul 2014

People with mild traumatic brain injury may have brain damage and memory problems

Even mild traumatic brain injury may cause brain damage and thinking and memory problems, according to a study published in the July 16, 2014, online issue of Neurology, the medical journal of the American Academy of Neurology.

17 Jul 2014

Scientists build artificial cells programmed to eat their undesirable neighbors

A team of researchers has devised a Pac-Man-style power pellet that gets normally mild-mannered cells to gobble up their undesirable neighbors. The development may point the way to therapies that enlist patients’ own cells to better fend off infection and even cancer, the researchers say. A description of the work will be published July 15 in the journal Science Signaling.

16 Jul 2014

Research sheds light on key mechanism prevalent in Alzheimer's disease patients

Alzheimer's disease affects approximately 5.2 million people in the United States alone, and it is the nation's sixth leading cause of death.

16 Jul 2014

Lilly, Immunocore enter into co-discovery and co-development collaboration to develop cancer therapies

Eli Lilly and Company and Immunocore Limited today announced they have entered into a co-discovery and co-development collaboration to research and potentially develop novel T cell-based cancer therapies.

16 Jul 2014

Study reveals way to alleviate memory deficits for Alzheimer's disease patients

A new study from the Gladstone Institutes has revealed a way to alleviate the learning and memory deficits caused by apoE4, the most important genetic risk factor for Alzheimer's disease, improving cognition to normal levels in aged mice.

16 Jul 2014

Study: Fish oil supplements reduce cognitive decline, brain atrophy in older adults

Rhode Island Hospital researchers have completed a study that found regular use of fish oil supplements (FOS) was associated with a significant reduction in cognitive decline and brain atrophy in older adults.

16 Jul 2014

New avenues for treatment of Alzheimer's disease

Judes Poirier, PhD, C.Q., from the Douglas Mental Health Institute and McGill University in Montr-al (Canada) and his team have discovered that a relatively frequent genetic variant actually conveys significant protection against the common form of Alzheimer's disease and can delay the onset of the disease by as much as 4 years.

15 Jul 2014

Neuroprotective effects of ginsenoside Rb1 on hippocampal neuronal injury, neurite outgrowth

The main pathological changes of Alzheimer's disease (AD) include amyloid-beta protein-induced hippocampal neuronal injury and neurite outgrowth impairment.

15 Jul 2014

Alzheimer's Disease News and Research

Further Reading

Deleting enzyme favorably impacts behaviors associated with autistic behaviors

New therapeutic interventions that target brain regions can prevent obesity

Compounds developed for cancer treatment show promise as potential oral therapy for Alzheimer's

Monitoring pulse regularly after stroke helps prevent next stroke

Study reveals novel epilepsy pathway linked to neurodegenerative diseases

Signs and symptoms of Lewy body dementia

Study finds microglia increase neuronal firing and enhance brain cell survival after injury

New discovery links two important hypotheses in Alzheimer's disease research

Elevated ASM activity linked to Alzheimer's disease

Brain network measures placebo effects in Parkinson's disease patients

Moxibustion and electroacupuncture alleviate neuronal cytoplasmic edema in AD

Structural change in periventricular white matter may show correlation with cognitive, sensory motor deficits by aging

People with mild traumatic brain injury may have brain damage and memory problems

Scientists build artificial cells programmed to eat their undesirable neighbors

Research sheds light on key mechanism prevalent in Alzheimer's disease patients

Lilly, Immunocore enter into co-discovery and co-development collaboration to develop cancer therapies

Study reveals way to alleviate memory deficits for Alzheimer's disease patients

Study: Fish oil supplements reduce cognitive decline, brain atrophy in older adults

New avenues for treatment of Alzheimer's disease

Neuroprotective effects of ginsenoside Rb1 on hippocampal neuronal injury, neurite outgrowth

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