Alzheimer's Disease News and Research

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Alzheimer's disease (AD) is an irreversible, progressive brain disease that slowly destroys memory and thinking skills and, eventually, the ability to carry out the simplest tasks of daily living. In most people with AD, symptoms first appear after age 60. AD is the most common cause of dementia among older people, but it is not a normal part of aging. Dementia refers to a decline in cognitive function that interferes with daily life and activities. AD starts in a region of the brain that affects recent memory, then gradually spreads to other parts of the brain. Although treatment can slow the progression of AD and help manage its symptoms in some people, currently there is no cure for this devastating disease.

B vitamins do not prevent Alzheimer's disease

Taking B vitamins doesn't slow mental decline as we age, nor is it likely to prevent Alzheimer's disease, conclude Oxford University researchers who have assembled all the best clinical trial data involving 22,000 people to offer a final answer on this debate.

15 Jul 2014

BAI and Novartis determine whether investigational drugs can prevent symptoms of Alzheimer's

Researchers from the Banner Alzheimer's Institute (BAI) today announced a partnership with Novartis in a pioneering medical trial to determine whether two investigational anti-amyloid drugs-an active immunotherapy and an oral medication-can prevent or delay the emergence of symptoms of Alzheimer's in people at particularly high risk for developing the disease at older ages.

15 Jul 2014

New data on possible protective behaviors and dementia risk factors emerges at AAIC- 2014

Participation in activities that promote mental activity, and moderate physical activity in middle age, may help protect against the development of Alzheimer's disease and dementia in later life, according to new research reported today at the Alzheimer's Association International Conference- 2014 (AAIC- 2014) in Copenhagen.

15 Jul 2014

ADSC transplantation promotes adult neurogenesis in brains of Alzheimer's disease mice

Recent evidence has demonstrated that transplantation of mesenchymal stem cells can stimulate neurogenesis in the brain of adult rat or mouse models of Alzheimer's disease (AD) and improve tissue and function injury under the condition of cerebral ischemia.

14 Jul 2014

Noninvasive optical imaging device helps to detect changes linked with Alzheimer's disease

A noninvasive optical imaging device developed at Cedars-Sinai can provide early detection of changes that later occur in the brain and are a classic sign of Alzheimer's disease, according to preliminary results from investigators conducting a clinical trial in Australia.

14 Jul 2014

Eye exam for beta-amyloid correlates with levels in brain, detects people with Alzheimer's

A decreased ability to identify odors might indicate the development of cognitive impairment and Alzheimer's disease, while examinations of the eye could indicate the build-up of beta-amyloid, a protein associated with Alzheimer's, in the brain, according to the results of four research trials reported today at the Alzheimer's Association International Conference- 2014 (AAIC- 2014) in Copenhagen.

14 Jul 2014

Cataract surgery for people with dementia slows cognition decline, improves quality of life

Cataract surgery for people with Alzheimer's disease and other dementias not only improves vision but can slow decline in cognition and improve quality of life for both people with the disease and their caregivers, according to clinical trial results reported today at the Alzheimer's Association International Conference 2014 (AAIC 2014) in Copenhagen.

13 Jul 2014

2D IR spectroscopy reveals intermediate structure during amylin aggregation pathway

Amyloid diseases, such as Alzheimer's disease, type 2 diabetes, cataracts, and the spongiform encephalopathies, all share the common trait that proteins aggregate into long fibers which then form plaques.

11 Jul 2014

BrightFocus offers grants to 55 scientists for Alzheimer's disease and vision research

BrightFocus Foundation, a nonprofit organization funding cutting-edge, innovative research on Alzheimer's disease and the vision diseases of glaucoma and macular degeneration, today announced the recipients of new research grant awards, offered to 55 scientists in 19 U.S. states, the District of Columbia, and five foreign countries.

11 Jul 2014

Researchers examine which teens have emotional symptoms after concussion

After a concussion, teens who are sensitive to light or noise may be more likely to also have emotional symptoms such as anxiety, according to a study released today that will be presented at The Sports Concussion Conference in Chicago, July 11 to 13, 2014, hosted by the American Academy of Neurology, the world's leading authority on diagnosing and managing sports concussion.

11 Jul 2014

New paper states that doctors have ethical obligation to educate, protect athletes from concussion

The American Academy of Neurology (AAN), the largest professional association of neurologists and a leading authority on sports concussion, is releasing a new position paper that states doctors have an ethical obligation to educate and protect athletes from sports concussion and clear them to play only when the athlete is medically ready, standing firm against objections from players, parents or coaches.

10 Jul 2014

Rockefeller scientists identify protein that makes breast cancer cells more likely to metastasize

Using an innovative tool that captures heretofore hidden ways that cells are regulated, scientists at Rockefeller University have identified a protein that makes breast cancer cells more likely to metastasize.

10 Jul 2014

New therapeutic targets release mechanisms in reactive astrocytes for treatment of Alzheimer's disease

Alzheimer's disease, which is the most common cause of dementia, is fatal and currently, there is no cure. In Alzheimer's disease, brain cells are damaged and destroyed, leading to devastating memory loss.

9 Jul 2014

UCLA project receives $15M to restore lost memory functions in brain-injured people

The UCLA Program in Memory Restoration has been awarded up to $15 million by the Defense Advanced Research Projects Agency (DARPA) for a four -year project aiming to help brain-injured people restore lost memory functions.

9 Jul 2014

CWRU receives $12.6 million from NIA to identify rare genetic variants that contribute to Alzheimer's

Researchers from Case Western Reserve University School of Medicine are part of a five-university collaboration receiving a $12.6 million, four-year grant from the National Institute on Aging (NIA), part of the National Institutes of Health (NIH), to identify rare genetic variants that may either protect against, or contribute to Alzheimer's disease risk.

8 Jul 2014

MEF2 gene: A potential therapeutic target to protect neuronal loss in Alzheimer's, Parkinson's

A new study by researchers at Sanford-Burnham Medical Research Institute (Sanford-Burnham) has identified a chemical "switch" that controls both the generation of new neurons from neural stem cells and the survival of existing nerve cells in the brain.

4 Jul 2014

Researchers confirm anecdotal information on Alzheimer's disease and cerebrovascular disease

Researchers from the Sanders-Brown Center on Aging at the University of Kentucky have been able to confirm anecdotal information on patients with both Alzheimer's disease (AD) and cerebrovascular disease (CVD) using mouse models in two different studies.

4 Jul 2014

Researchers confirm anecdotal information on patients with Alzheimer's disease, CVD

4 Jul 2014

Persons with reduced levels of TREM2 protein at greater risk for neurodegenerative diseases

Persons with reduced levels of the TREM2 protein could be at greater risk of developing neurodegenerative diseases such as Alzheimer's disease or frontotemporal dementia, according to an international study which included the participation of the Universitat Autònoma de Barcelona and the Sant Pau Biomedical Research Institute.

3 Jul 2014

Analysis of clinical trials reveals urgent need to increase Alzheimer's drug development

Researchers at the Cleveland Clinic Lou Ruvo Center for Brain Health have conducted the first-ever analysis of clinical trials for Alzheimer's disease (AD), revealing an urgent need to increase the number of agents entering the AD drug development pipeline and progressing successfully towards new therapy treatments.

3 Jul 2014

Alzheimer's Disease News and Research

Further Reading

B vitamins do not prevent Alzheimer's disease

BAI and Novartis determine whether investigational drugs can prevent symptoms of Alzheimer's

New data on possible protective behaviors and dementia risk factors emerges at AAIC- 2014

ADSC transplantation promotes adult neurogenesis in brains of Alzheimer's disease mice

Noninvasive optical imaging device helps to detect changes linked with Alzheimer's disease

Eye exam for beta-amyloid correlates with levels in brain, detects people with Alzheimer's

Cataract surgery for people with dementia slows cognition decline, improves quality of life

2D IR spectroscopy reveals intermediate structure during amylin aggregation pathway

BrightFocus offers grants to 55 scientists for Alzheimer's disease and vision research

Researchers examine which teens have emotional symptoms after concussion

New paper states that doctors have ethical obligation to educate, protect athletes from concussion

Rockefeller scientists identify protein that makes breast cancer cells more likely to metastasize

New therapeutic targets release mechanisms in reactive astrocytes for treatment of Alzheimer's disease

UCLA project receives $15M to restore lost memory functions in brain-injured people

CWRU receives $12.6 million from NIA to identify rare genetic variants that contribute to Alzheimer's

MEF2 gene: A potential therapeutic target to protect neuronal loss in Alzheimer's, Parkinson's

Researchers confirm anecdotal information on Alzheimer's disease and cerebrovascular disease

Researchers confirm anecdotal information on patients with Alzheimer's disease, CVD

Persons with reduced levels of TREM2 protein at greater risk for neurodegenerative diseases

Analysis of clinical trials reveals urgent need to increase Alzheimer's drug development

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