Enzyme News and Research

RSS

Pandorabactins help pathogenic bacteria compete for iron in the lungs

An interdisciplinary research team led by the Leibniz-HKI in Jena has discovered a new group of bioactive natural compounds in pathogenic bacteria of the genus Pandoraea: pandorabactins.

19 Jun 2025

Study finds high levels of iron in the brains of people diagnosed with Down syndrome and Alzheimer's

Scientists at the USC Leonard Davis School of Gerontology have discovered a key connection between high levels of iron in the brain and increased cell damage in people who have both Down syndrome and Alzheimer's disease.

19 Jun 2025

Time-restricted feeding restores microbial rhythms and boosts metabolism

The gut microbiome, a vast assortment of bacteria and other microorganisms that inhabit our digestive system, plays a critical role in converting food into energy.

19 Jun 2025

Inhibiting RNA Polymerase 1 suppresses tumor growth in hard-to-treat cancers

Researchers at the Johns Hopkins Kimmel Cancer Center and Department of Radiation Oncology and Molecular Radiation Sciences uncovered a new tumor-suppressive response that could lead to novel therapies targeting hard-to-treat cancers.

18 Jun 2025

Yale researchers triple precision and efficiency in genome editing

The promise of genome editing to help understand human diseases and create new therapies is vast, but technological limitations have limited advancement of the field.

18 Jun 2025

UQ researchers discover new lipid-based pathway essential for memory formation

A new lipid-based pathway essential for memory formation has been discovered by University of Queensland researchers – a breakthrough that could lead to treatments for post-traumatic stress disorder (PTSD).

18 Jun 2025

PDE3 inhibitors show promise in promoting bone growth

Bone growth occurs through the proliferation of specialized cells of the cartilage tissue, known as chondrocytes, on either end of a bone.

17 Jun 2025

Researchers identify a new treatment strategy for neuroblastoma

Researchers at Karolinska Institutet and Lund University in Sweden have identified a new treatment strategy for neuroblastoma, an aggressive form of childhood cancer.

16 Jun 2025

Solascure receives FDA Fast Track Designation for Aurase Wound Gel to treat calciphylaxis ulcers

SOLASCURE Ltd (SolasCure), a biotechnology company developing a novel treatment to transform chronic wound healing, today announced that the US Food and Drug Administration (FDA) has granted Fast Track Designation for its investigational Aurase Wound Gel (AWG), in the treatment of patients with calciphylaxis ulcers.

16 Jun 2025

Statins could reduce breast cancer mortality by a fifth

Research indicates statins could enhance breast cancer prognosis, with lipophilic statins showing greater protective effects against mortality and recurrence.

16 Jun 2025

Understanding the role of astrocytes in depression and neuroinflammation

Major depressive disorder (MDD) is a mental health condition that negatively affects the mood of a person and causes a loss of interest in activities that were previously associated with happiness.

13 Jun 2025

Yellow pigment linked to protection against severe malaria

New research suggests that a pigment that causes yellowing of the skin, or jaundice, may help protect people from the most severe consequences of malaria.

13 Jun 2025

New CRISPR tool enables precise chemical modification of RNA in living cells

CRISPR-Cas13, a powerful RNA-targeting technology is gaining increasing attention as a next-generation gene therapy platform due to its precision and reduced side effects.

12 Jun 2025

Blocking a single enzyme rewires limb regrowth in axolotls

Researchers uncovered how CYP26B1-mediated retinoic acid (RA) breakdown determines segment identity during axolotl limb regeneration. Disrupting RA degradation reprograms blastema cells, revealing the molecular controls of precise limb regrowth.

11 Jun 2025

New therapeutic approach targets PCSK9 to regulate blood cholesterol levels

When the amount of cholesterol in the blood is too high, hypercholesterolemia can develop, causing serious damage to the arteries and cardiovascular health.

11 Jun 2025

Structural insights into IVD enzyme function and isovaleric acidemia

IVD is a key enzyme in leucine catabolism, catalyzing the conversion of isovaleryl-CoA to 3-methylcrotonyl-CoA.

10 Jun 2025

Smartwatch alerts retired nurse to heart injury, prompting life-saving hospital care

A smartwatch detected abnormal ECG changes in a 76-year-old woman experiencing chest pain following emotional stress. Hospital investigations confirmed takotsubo (stress) cardiomyopathy, highlighting the potential and limitations of wearable health technology in acute cardiac care.

10 Jun 2025