Insulin News and Research

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Insulin is a hormone that is needed to convert glucose, starches and other food into energy needed for daily life. Insulin allows cells to use glucose for fuel and is secreted by beta cells in the islets of Langerhans. The release of insulin from the pancreas is stimulated by increased blood glucose, vagal nerve stimulation, and other factors. Insulin is obtained from various animals and available in a variety of preparations. Commercial insulin preparations differ in a number of ways, including differences in the animal species from which they are obtained; their purity, concentration, and solubility; and the time of onset and duration of their biologic action. An oral hypoglycemic agent is not a form of insulin therapy.

Research finds long-term health challenges in survivors of childhood cancer

Researchers at City of Hope, one of the largest and most advanced cancer research and treatment organizations in the United States with its National Medical Center ranked among the nation's top cancer centers by U.S. News & World Report, today published a new study which found that some survivors of childhood cancer are more at risk for serious health issues as they grow older, including new cancers and chronic conditions like heart disease.

11 Aug 2025

Fifteen-year study shows major gains in diabetes technology use and patient outcomes

A new study led by researchers at the Johns Hopkins Bloomberg School of Public Health found big increases in the use of continuous glucose monitoring and insulin delivery devices by children and adults with type 1 diabetes over a 15-year period, with corresponding jumps in optimal blood-sugar control.

11 Aug 2025

Brain’s energy control map offers blueprint for next-gen weight loss therapies

Scientists map how the brain integrates hormonal and neural signals from the body to control appetite, energy use, and reward pathways, revealing targets for next-generation anti-obesity drugs. This review highlights the interplay between neuroendocrine circuits, neuroplasticity, and pharmacotherapy for durable, non-aversive weight loss.

11 Aug 2025

Implant system can treat Type 1 diabetes by supplying extra oxygen to insulin-secreting cells

Cornell researchers have developed an implant system that can treat Type 1 diabetes by supplying extra oxygen to densely packed insulin-secreting cells, without the need for immunosuppression.

11 Aug 2025

Mothers face greater financial impact following child’s type 1 diabetes diagnosis

Parents of children diagnosed with type 1 diabetes suffer an income drop in the years following the diagnosis.

11 Aug 2025

Why young Americans dread turning 26: Health insurance chaos

Amid the challenges of adulthood, one rite of passage is unique to the United States: the need to find your own health insurance by the time you turn 26.

11 Aug 2025

Vital role of physical activity in early type 2 diabetes care

New research to be presented at this year's Annual Meeting of the European Association for the Study of Diabetes (EASD) in Vienna, Austria (15-19 September) shows, among people recently diagnosed with type with type 2 diabetes and no previous cardiovascular disease, a clear association exists between a person's self-reported physical activity and their risk of all-cause mortality and major adverse cardiac events (MACE), that include heart attacks and strokes.

8 Aug 2025

How too much screen time affects kids’ heart health and what can reduce the risk

A large Danish cohort study found that higher screen time in childhood and adolescence is linked to worse cardiometabolic health, with shorter sleep amplifying the risk. Blood metabolomics revealed a signature of high screen time, and in teens, it was tied to higher predicted cardiovascular disease risk.

7 Aug 2025

Researchers uncover dozens of traits driven by maternal versus paternal genes

Researchers developed a high-accuracy method to infer whether genetic variants come from the mother or father without needing parental genomes, analysing 286,666 UK Biobank participants. They uncovered over 30 parent-of-origin effects on traits from growth and metabolism to diabetes, many showing opposite effects depending on parental source.

7 Aug 2025

Personalizing endometrial cancer prevention through diet and lifestyle

This review synthesizes emerging evidence on modifiable risk factors for endometrial cancer (EC)-the sixth most common female malignancy globally-with rising incidence despite diagnostic advances.

7 Aug 2025

Vitamin D supplementation linked to improved cardiometabolic health

A latest systematic review and meta-analysis conducted by scientists from institutions across China and the United States has uncovered promising insights into how vitamin D supplementation can significantly impact cardiometabolic health.

6 Aug 2025

Immune aging drives the progression of type 2 diabetes

Type 2 diabetes (T2D) is a global metabolic epidemic driven by insulin resistance (IR), chronic inflammation, and β-cell failure.

6 Aug 2025

Diabetes drug linked to lower risks of dementia and early death

New research in Diabetes, Obesity and Metabolism reveals that metformin, a medication traditionally prescribed to treat diabetes, is linked to lower risks of dementia and early death.

6 Aug 2025

Excessive screen time linked to higher cardiometabolic risk in youth

Children and young adults who spend excessive hours glued to screens and electronic devices may have higher risks for cardiometabolic diseases, such as high blood pressure, high cholesterol and insulin resistance, according to new research published today in the Journal of the American Heart Association, an open-access, peer-reviewed journal of the American Heart Association.

6 Aug 2025

Research offers hope for weight loss without gastrointestinal distress

Weight loss and diabetes drugs on the market often do not achieve long-term weight loss for patients. GLP-1 drugs target brain neurons that control appetite but frequently cause side effects.

5 Aug 2025

Leptin could offer alternative to insulin for managing type 1 diabetes complication

More than a decade ago, researchers found that an acute complication of type 1 diabetes, diabetic ketoacidosis (DKA), can be resolved with the hormone leptin, even in the absence of insulin.

4 Aug 2025

Living in rural areas early in life may increase risk of type 1 diabetes

New research to be presented at this year's Annual Meeting of the European Association for the Study of Diabetes (EASD) in Vienna, Austria (15-19 September) suggests that living in a rural environment in the first five years of life could increase the risk of developing type 1 diabetes compared with living in urban environments.

4 Aug 2025

Metformin’s blood sugar control starts in the brain, not just the liver, study finds

Low, clinically relevant doses of metformin lower blood glucose by inhibiting the Rap1 protein in specific neurons of the hypothalamus, revealing a brain-first mechanism. This action is essential for metformin’s effect at therapeutic doses and highlights new directions for diabetes treatment.

3 Aug 2025

Immune molecule found to play a key role in regulating inflammation in rheumatoid arthritis

Researchers at Kyoto University have discovered that an immune molecule found only in primates, called IGFL2, plays a key role in regulating inflammation in rheumatoid arthritis (RA).

1 Aug 2025

New approach preserves insulin-producing cells in diabetes model

Scientific breakthroughs in one disease don't always shed light on treating other diseases. But that's been the surprising journey of one Mayo Clinic research team.

1 Aug 2025

Insulin News and Research

Further Reading

Research finds long-term health challenges in survivors of childhood cancer

Fifteen-year study shows major gains in diabetes technology use and patient outcomes

Brain’s energy control map offers blueprint for next-gen weight loss therapies

Implant system can treat Type 1 diabetes by supplying extra oxygen to insulin-secreting cells

Mothers face greater financial impact following child’s type 1 diabetes diagnosis

Why young Americans dread turning 26: Health insurance chaos

Vital role of physical activity in early type 2 diabetes care

How too much screen time affects kids’ heart health and what can reduce the risk

Researchers uncover dozens of traits driven by maternal versus paternal genes

Personalizing endometrial cancer prevention through diet and lifestyle

Vitamin D supplementation linked to improved cardiometabolic health

Immune aging drives the progression of type 2 diabetes

Diabetes drug linked to lower risks of dementia and early death

Excessive screen time linked to higher cardiometabolic risk in youth

Research offers hope for weight loss without gastrointestinal distress

Leptin could offer alternative to insulin for managing type 1 diabetes complication

Living in rural areas early in life may increase risk of type 1 diabetes

Metformin’s blood sugar control starts in the brain, not just the liver, study finds

Immune molecule found to play a key role in regulating inflammation in rheumatoid arthritis

New approach preserves insulin-producing cells in diabetes model

Lab Matters host Harriet Gould on building a more connected lab community

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

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