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Computational model can help predict cellular drug targets against COVID-19

A computational model of a human lung cell has been used to understand how SARS-CoV-2 draws on human host cell metabolism to reproduce by researchers at the University of Warwick.

25 Nov 2020

Digital warm-start CRISPR assay enables sensitive quantitative detection of SARS-CoV-2 in clinical samples

In a recent medRxiv* preprint paper, researchers from the University of Connecticut Health Center in the United States unveil their digital warm-start CRISPR (WS-CRISPR) method for stringent and sensitive quantitative detection of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in clinical samples of patients with coronavirus disease (COVID-19).

24 Nov 2020

Measurement of Cancer Biomarker Enrichment in Exosomes

Postnova Analytics reports that researchers from the University of Utah (Salt Lake City, USA) have used a novel combination of Asymmetrical Flow Field-Flow Fractionation and Centrifugal Field-Flow Fractionation to measure cancer biomarker enrichment in exosomes.

From Postnova Analytics 24 Nov 2020

Greensboro North Carolina Company’s Dedication to Ensuring Laboratories have COVID-19 Supplies Now Offers One-Stop-Shop for PCR Instruments, Extraction Systems and Kits, POC COVID-19 Test Kits, and Supplies.

GREENSBORO, NC — (November 20, 2020) – Greensboro-based, Carolina Liquid Chemistries Corp. (CLC) has been tirelessly working since the beginning of the COVID-19 outbreak to provide high-quality testing kits and instruments to healthcare providers and laboratories as quickly as possible.

From Carolina Liquid Chemistries Corp. 23 Nov 2020

Chicago seroprevalence study shows COVID-19 cases 16 times higher than currently predicted

A startling new case study of Chicago, led by a team of researchers at Northwestern University in Illinois, USA, suggests a 16-fold higher incidence of SARS-CoV-2 infection than previously thought. This is judging from seroprevalence (antibody presence blood testing) figures, rather than the number of RT-PCR-positives reported there (via swab sample testing of symptomatic patients).

23 Nov 2020

New multiplex assay can be used for epidemiological surveillance, management of COVID-19

Scientists from Northwell Health Laboratories have developed a new diagnostic multiplex assay that can be used for epidemiological surveillance and clinical management of COVID-19.

17 Nov 2020

Peptide-conjugated morpholino oligomers effectively inhibit SARS-CoV-2 in vero cells

The hunt for antivirals has reached an unprecedented pace in light of the coronavirus 2019 (COVID-19) pandemic. The causal agent for this disease – severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – has already infected over 52 million people worldwide, and has subsequently claimed over 1.3 million lives. However, among the innumerable promising drug candidates that help battle the virus and mitigate its damage, none have yet made it to the clinic.

12 Nov 2020

Spike-based DNA vaccine shows excellent protection against SARS-CoV-2 in a hamster model

A study conducted at the United States Army Research Institute of Infectious Diseases shows how a relatively simple full-length DNA vaccine against spike glycoprotein of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can elicit neutralizing antibody response in an animal model – even after a single shot with simple jet injection technique.

11 Nov 2020

SARS-CoV-2 RNA genome structure reveals potential targets for development of drugs

The SARS-CoV-2 coronavirus RNA genome structure was studied in detail by researchers from the University of Groningen, the International Institute of Molecular and Cell Biology in Warsaw, and Leiden University.

10 Nov 2020

A digital CRISPR-based method for quick detection and absolute quantification of SARS-CoV-2

In a recent medRxiv* preprint manuscript, researchers from Singapore and the United States report the development of a digital CRISPR method for the sensitive, specific, and rapid detection of viral nucleic acids at a constant temperature, which could be exploited for the detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

5 Nov 2020

Stanford researchers create a highly automated device that can detect COVID-19 in 30 minutes

Throughout the pandemic, infectious disease experts and frontline medical workers have asked for a faster, cheaper and more reliable COVID-19 test.

5 Nov 2020

Porvair Sciences introduces new 2.2ml 96 deep well plate for SARS-CoV-2 nucleic acid purification

Porvair Sciences has introduced a new 2.2ml 96 deep well plate specifically designed to be fully compatible with the Thermo Scientific™ KingFisher™ range of nucleic acid purification systems.

From Porvair Sciences Limited 2 Nov 2020

Hospital floors create route of transfer of potentially dangerous organisms to patients

The floors of hospital rooms are quickly and frequently contaminated with antibiotic-resistant bacteria within hours of patient admission, creating a route of transfer of potentially dangerous organisms to patients, according to a study published today as part of the proceedings from Decennial 2020: The Sixth International Conference on Healthcare-Associated Infections.

30 Oct 2020

Simple method provides real-time surveillance to control the spread of drug-resistant gonorrhea

A dual therapy treatment regimen of expanded-spectrum cephalosporins (ESCs) plus azithromycin (AZM) is the recommended standard of care for gonorrhea.

27 Oct 2020

EKF launches PrimeStore® MTM pathogenic sample collection and transportation kit

EKF Diagnostics, the global in-vitro diagnostics company, announces that it has launched a PrimeStore® MTM sample collection kit.

From EKF Diagnostics 26 Oct 2020

Biomimetic virus-like particles for safer positive controls in SARS-CoV-2 detection

In an attempt to overcome these issues, a team of researchers from various departments at the University of California San Diego recently proposed using biomimetic virus-like particles (VLPs) as positive controls for assays used in SARS-CoV-2 detection. Their study is published on the preprint server bioRxiv.

23 Oct 2020

Researchers explore new method to monitor the effectiveness of HIV treatment at home

Development of a new method to monitor the effectiveness of human immunodeficiency virus (HIV) treatment at home instead of in hospitals is underway by Penn State researchers.

20 Oct 2020

Researchers develop new strategy to improve siRNA stability

RNA interference is a gene regulatory mechanism in which the expression of specific genes is downregulated by endogenous microRNAs or by small interfering RNAs (siRNAs).

16 Oct 2020

Porvair Sciences offers optimized microplates for affinity binding assays

Porvair Sciences new medium and high bind Krystal microplates set a new standard for uniform and reproducible capture of a wide range of biomolecules ready for affinity binding assays such as ELISA's.

From Porvair Sciences Limited 16 Oct 2020

New saliva tests can enable early detection and diagnosis of COVID-19, head & neck cancer

Summit Biolabs, Inc., an early-stage molecular diagnostics company specializing in saliva-based testing for COVID-19 and head & neck cancer, and the Colorado Center for Personalized Medicine (CCPM) at the University of Colorado Anschutz Medical Campus announced today a broad strategic collaboration involving research, development and commercialization of saliva liquid-biopsy tests for early cancer detection and diagnosis of COVID-19 and other viral contagions.

15 Oct 2020