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New gene therapy strategy reactivates dormant genes to treat blood disorders

Researchers have found a promising new method for gene therapy. They successfully restarted inactive genes by bringing them closer to genetic switches on the DNA called enhancers.

19 Jun 2025

Wildfire smoke and heat stress impact birth outcomes in vulnerable communities

Exposure to wildfire smoke and heat stress can negatively affect birth outcomes for women, especially in climate-vulnerable neighborhoods, according to a recent study led by USC postdoctoral researcher Roxana Khalili, PhD.

19 Jun 2025

Global guideline released by WHO on managing sickle cell disease in pregnancy

The World Health Organization (WHO) today released its first-ever global guideline on the management of sickle cell disease (SCD) during pregnancy, addressing a critical and growing health challenge that can have life-threatening consequences for both women and babies.

19 Jun 2025

Rapid generation of functional blood vessels from human stem cells

Blood vessels are essential to nearly all tissues, delivering nutrients and oxygen, regulating hemostasis, and modulating inflammation.

14 Jun 2025

Researchers identify cellular hotspots that trigger ferroptosis

Researchers at the VIB-KU Leuven Center for Cancer Biology have uncovered how a unique interaction between two cellular compartments, namely the endoplasmic reticulum (ER) and mitochondria, can act as a central ignition point for ferroptosis, a form of cell death driven by lipid oxidation and iron.

14 Jun 2025

Mapping genetic activity offers new clues for personalized cancer treatment

City of Hope®, one of the largest and most advanced cancer research and treatment organizations in the U.S. with its National Medical Center named top 5 in the nation for cancer by U.S. News & World Report, co-led the first study to demonstrate that characterizing genetic material near chromosomes forecasts how mutated, cancer-causing genes reengineer DNA and alter the tumor microenvironment.

13 Jun 2025

3D bioprinting takes major step forward with realistic blood vessel structures

There are more than 100,000 people on organ transplant lists in the U.S., some of whom will wait years to receive one – and some may not survive the wait. Even with a good match, there is a chance that a person's body will reject the organ.

13 Jun 2025

Study uncovers molecular mechanism behind 'ticking' of the circadian clock in cyanobacteria

Researchers from the Institute for Molecular Science (IMS)/SOKENDAI and Kyushu University have uncovered the molecular mechanism that drives the "ticking" of the circadian clock in cyanobacteria.

13 Jun 2025

New hypothesis links caffeine to lower risk of sudden infant death syndrome

After decades of stalled national progress in reducing the rate of Sudden Unexpected Infant Death (SUID), a category of infant mortality that includes sudden infant death syndrome (SIDS), researchers at Rutgers Health have proposed an unexpected solution: Caffeine might protect babies by preventing dangerous drops in oxygen that may trigger deaths.

11 Jun 2025

Predicting deep vein thrombosis in patients with epithelial ovarian cancer using a nomogram

Nomograms have a strong reputation as reliable predictive models that simplify statistical prediction models and guide personalized treatment to formulate preventive measures for various diseases.

11 Jun 2025

Targeting metabolic reprogramming in breast cancer treatment

Breast cancer remains the most prevalent malignancy among women worldwide, posing a critical challenge to global health.

11 Jun 2025

Inhibiting cancer cells' energy source with natural acid ester

Looking to nature for answers to complex questions can reveal new and unprecedented results that can even affect cells on molecular levels.

10 Jun 2025

Energy drain from antibiotics spurs bacteria to resist treatment faster

Antibiotics are supposed to wipe out bacteria, yet the drugs can sometimes hand microbes an unexpected advantage.

9 Jun 2025

New study warns of long-term risks from fecal microbiota transplants

Fecal microbiota transplants (FMT) have been touted as a potential treatment for a variety of conditions, from inflammatory bowel diseases, obesity, and type 2 diabetes to autism.

6 Jun 2025

Mitochondrial DNA variant predicts resistance to melanoma immunotherapy

Results from a new study help resolve the decade-long mystery of why many patients with the deadliest form of skin cancer do not respond to the latest cancer treatments.

6 Jun 2025

Alcohol and cabin pressure may harm heart health during flights

The combination of alcohol plus cabin pressure at cruising altitude may threaten sleeping plane passengers' heart health, particularly on long haul flights, suggests the first study of its kind, published online in the respiratory journal Thorax.

6 Jun 2025

Stanford scientists grow vascularized heart and liver organoids

For over a decade, scientists have been growing organoids - small clusters of cells that mimic a particular organ - to serve as miniature biological models.

6 Jun 2025

New anti-aging compounds found hidden beneath the skin

People go to great lengths to maintain youthful-looking skin with masks, creams and serums. Now, researchers have discovered compounds with anti-aging properties hidden beneath our own skin.

5 Jun 2025

Using Swarm Learning approach to aid doctors in treating stroke patients

Researchers at DZNE and the Department of Vascular Neurology at the University Hospital Bonn (UKB) aim to develop a computer model based on artificial intelligence (AI) to aid doctors in treating stroke patients.

5 Jun 2025

Genetic mutation identified as key factor in immunotherapy resistance for melanoma

Tests in 1,225 patients with the most deadly form of skin cancer reveal for the first time a genetic trait among most of those who did not respond to the latest cancer treatments, known as immune checkpoint inhibitors.

5 Jun 2025