Oncology News and Research

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Oncology, meaning bulk, mass, or tumor, and the suffix ''-logy'', meaning "study of") is a branch of medicine that deals with tumors (cancer). A medical professional who practices oncology is an ''oncologist''.

Mayo Clinic study: Increasing physical activity decreases risk of death from lymphoma

An observational study by researchers at Mayo Clinic has found that increasing physical activity not only decreased the risk of death from all causes but also decreased the risk of death specifically from lymphoma.

13 Dec 2017

FDA researchers find underrepresentation of adults aged 75 years and older in blood cancer clinical trials

In the first comprehensive analysis of clinical trial enrollment among older adults with blood cancers, researchers from the U.S. Food and Drug Administration found significant gaps in participation among those aged 75 and older when considered against the incidence of these malignancies in this age group, according to research being presented today during the 59th American Society of Hematology Annual Meeting and Exposition in Atlanta.

12 Dec 2017

Study provides new insights into mechanism of tumor survival in glioblastoma

A Northwestern Medicine study, published in the journal Cancer Cell, has provided new insights into a mechanism of tumor survival in glioblastoma and demonstrated that inhibiting the process could enhance the effects of radiation therapy.

11 Dec 2017

Scientists develop software that predicts leukemia-specific immune targets

University of North Carolina Lineberger Comprehensive Cancer Center scientists have developed a software program that can accurately predict which tumor-specific markers will show up on the surface of leukemia cells in patients who have received stem cell transplants.

11 Dec 2017

Soy foods, cruciferous vegetables may reduce breast cancer treatment’s side effects

Consuming soy foods (such as soy milk, tofu and edamame) and cruciferous vegetables (such as cabbages, kale, collard greens, bok choy, Brussels sprouts, and broccoli) may be associated with a reduction in common side effects of breast cancer treatment in breast cancer survivors, say a team of scientists led by Georgetown Lombardi Comprehensive Cancer Center.

11 Dec 2017

CAR T cell therapy shows long-lasting remissions in non-Hodgkin's lymphoma patients

In a pair of clinical trials stretching from Philadelphia to Tokyo, the chimeric antigen receptor (CAR) T cell therapy Kymriah (formerly known as CTL019) demonstrated long-lasting remissions in non-Hodgkin's lymphoma (NHL) patients.

11 Dec 2017

Two immunotherapy approaches for multiple myeloma show hope

Researchers from the University of Pennsylvania's Abramson Cancer Center have developed two experimental immunotherapy methods that include one chimeric antigen receptor (CAR) T cell therapy for the treatment of multiple myeloma patients who were not responding to other treatments.

11 Dec 2017

Novel compound along with checkpoint inhibitors may enhance immune response in melanoma patients

A novel compound may restore immune response in patients with melanoma, according to a study presented at the ESMO Immuno Oncology Congress 2017.

8 Dec 2017

Simple molecular test may help predict presence of high-grade pancreatic cancers

A report in The Journal of Molecular Diagnostics, describes a new simple molecular test to detect chromosomal abnormalities -- biomarkers known as telomere fusions--in pancreatic tumor specimens and pancreatic cyst fluids.

8 Dec 2017

Study finds mechanism of resistance to checkpoint inhibitors and way to reverse it

Researchers have discovered a mechanism of resistance to checkpoint inhibitors and how to reverse it. The biomarker results from the IMvigor210 study are reported at the ESMO Immuno Oncology Congress 2017.

8 Dec 2017

PARP inhibitor can be new treatment option for patients with metastatic breast cancer, BRCA mutations

In a randomized, Phase III trial led by researchers at The University of Texas MD Anderson Cancer Center, the PARP inhibitor talazoparib extended progression-free survival (PFS) and improved quality-of-life measures over available chemotherapies for patients with metastatic HER2-negative breast cancer and mutations in the BRCA1/2 genes.

8 Dec 2017

Family members who do not carry inherited mutation have higher risk of melanoma

In families who carry certain inherited mutations that increase the risk for melanoma, members who do not carry the mutation also have an increased risk of melanoma, a study from Karolinska Institutet published in Genetics in Medicine reports.

8 Dec 2017

New first line combination therapy shows promising results in patients with advanced NSCLC

A new combination therapy for the first line treatment of advanced non-squamous non-small-cell lung cancer (NSCLC) improves progression-free survival (PFS), according to results of phase III IMpower150 trial presented at the ESMO Immuno Oncology Congress 2017.

7 Dec 2017

Fusobacterium may play role in colon cancer growth, study finds

Like nomads who carry tokens of home on their travels, colorectal cancer cells that spread to other parts of the body appear to bring several of the species of bacteria that were their companions in the colon, Dana-Farber Cancer Institute scientists report in a new study in the journal Science.

7 Dec 2017

UMSOM researchers find two-way link between TBI and intestinal changes

University of Maryland School of Medicine researchers have found a two-way link between traumatic brain injury (TBI) and intestinal changes. These interactions may contribute to increased infections in these patients, and may also worsen chronic brain damage.

7 Dec 2017

Study shows how interplay between two key enzymes promotes brain tumor growth

Study results revealed previously unknown interplay between two key enzymes and a novel understanding of how brain cancer tumors form and spread, according to researchers at The University of Texas MD Anderson Cancer Center.

6 Dec 2017

Immune-boosting drug combination may hold promise for treating ovarian cancer

Johns Hopkins Kimmel Cancer Center researchers demonstrated that mice with ovarian cancer that received drugs to reactivate dormant genes along with other drugs that activate the immune system had a greater reduction of tumor burden and significantly longer survival than those that received any of the drugs alone.

5 Dec 2017

Shorter course of radiation may be preferred treatment for men with intermediate-risk prostate cancer

Prostate cancer is the most common cancer among males in the United States. Approximately, 180,000 men are diagnosed each year, and approximately 95 percent of these men have localized disease that is potentially curable.

5 Dec 2017

Overcoming Challenges of Assays of Complex Cellular Models with Real-Time Live-Cell Analysis

There's a continued drive towards making in vitro assays ever more translational towards in vivo models and ultimately the clinic. This ties in with the resurgence of phenotypic screening and is a response to the perceived poor translation of the traditional simple cell-based assays, often developed to study just single protein targets.

From Sartorius 5 Dec 2017

New biomarker test can accurately predict which chemical compounds induce DNA damage

A new biomarker test developed by researchers at Georgetown Lombardi Comprehensive Cancer Center and their colleagues can help predict, with up to 90 percent certainty, which chemical compounds can cause DNA damage that could lead to cancer.

5 Dec 2017

Oncology News and Research

Further Reading

Mayo Clinic study: Increasing physical activity decreases risk of death from lymphoma

FDA researchers find underrepresentation of adults aged 75 years and older in blood cancer clinical trials

Study provides new insights into mechanism of tumor survival in glioblastoma

Scientists develop software that predicts leukemia-specific immune targets

Soy foods, cruciferous vegetables may reduce breast cancer treatment’s side effects

CAR T cell therapy shows long-lasting remissions in non-Hodgkin's lymphoma patients

Two immunotherapy approaches for multiple myeloma show hope

Novel compound along with checkpoint inhibitors may enhance immune response in melanoma patients

Simple molecular test may help predict presence of high-grade pancreatic cancers

Study finds mechanism of resistance to checkpoint inhibitors and way to reverse it

PARP inhibitor can be new treatment option for patients with metastatic breast cancer, BRCA mutations

Family members who do not carry inherited mutation have higher risk of melanoma

New first line combination therapy shows promising results in patients with advanced NSCLC

Fusobacterium may play role in colon cancer growth, study finds

UMSOM researchers find two-way link between TBI and intestinal changes

Study shows how interplay between two key enzymes promotes brain tumor growth

Immune-boosting drug combination may hold promise for treating ovarian cancer

Shorter course of radiation may be preferred treatment for men with intermediate-risk prostate cancer

Overcoming Challenges of Assays of Complex Cellular Models with Real-Time Live-Cell Analysis

New biomarker test can accurately predict which chemical compounds induce DNA damage

Event guide: 10th CAR-TCR Summit eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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