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Nanozymes offer promise for treating inflammation during pregnancy

Special care must be taken with illnesses during pregnancy, as not all drugs are compatible for mother and child.

20 May 2025

Sucralose disrupts male fertility by damaging sperm and altering hormones in animal study

Researchers found that chronic sucralose exposure in male rats disrupted reproductive hormones, damaged sperm, and impaired testicular function through oxidative stress and autophagy dysregulation. These findings raise concerns about the reproductive risks of high sucralose intake and its persistent presence in the environment.

19 May 2025

Red blood cells drive blood vessel damage in diabetes by exporting toxic vesicles

Red blood cell-derived extracellular vesicles in type 2 diabetes are actively taken up by the endothelium, transferring the enzyme arginase-1 and triggering oxidative stress. This mechanism helps explain vascular complications in diabetes and offers new targets for therapeutic intervention.

19 May 2025

Zebrafish study reveals hidden dangers of environmental toxins from tires

Emerging contaminants from rubber tires N-(1,3-Dimethylbutyl)-N'-phenyl-p-phenylenediamine (6PPD) and its oxidation product 6PPD-quinone (6PPDQ)-are raising new red flags for aquatic ecosystems.

19 May 2025

EMA designates allopurinol as first orphan drug for the treatment of Marfan syndrome

The European Medicines Agency (EMA) has designated allopurinol as the first orphan drug for the treatment of Marfan syndrome, a rare connective tissue disease which as no cure to date.

19 May 2025

USPSTF urges universal syphilis screening in pregnancy to prevent congenital infections

The US Preventive Services Task Force (USPSTF) reaffirms its recommendation for universal syphilis screening in pregnancy, citing strong evidence for early detection and prevention of congenital syphilis. Despite ongoing disparities and rising rates, early screening and treatment remain essential to improving outcomes for mothers and infants.

18 May 2025

Newly discovered Cat1 protein halts viral infections by depleting cellular fuel

Every living creature on Earth needs to protect itself from things that would do it harm. Bacteria are no different. And despite their relative simplicity, they deploy remarkably savvy defensive strategies against viral invaders.

18 May 2025

Long noncoding RNA ESSENCE identified as key driver of colorectal cancer progression

Colorectal cancer (CRC) remains one of the most prevalent and deadly cancers worldwide, with rising incidence linked to dietary and lifestyle changes.

18 May 2025

Electromagnetic waves disrupt SARS-CoV-2 spike protein and lower infectivity

Researchers demonstrated that specific electromagnetic wave frequencies can disrupt the SARS-CoV-2 Spike protein structure in virus-like particles, leading to reduced infectivity in cell models. This proof-of-concept study suggests new avenues for non-chemical viral inactivation methods.

18 May 2025

Study reveals how acetaminophen may actually relieve pain

A new study from Indiana University scientists may aid the pharmaceutical industry in better understanding a popular over-the-counter pain reliever: Tylenol.

16 May 2025

Extracellular vesicle detection moves forward with nanophotonic sensing and label-free imaging

Proteins play a vital role in human health and detecting them is crucial in medical research and clinical practice.

16 May 2025

Targeting PME-1 may offer new strategies for treating neurological disorders and cancer

PME-1 is a protein that modifies other proteins by removing methyl groups, but high levels of PME-1 are observed in some diseases, including Alzheimer's disease (AD) and cancer.

16 May 2025

Optimer licensing agreements and repeat custom

Aptamer Group plc, the leading developer of next-generation synthetic binders delivering innovation to the life science industry, has announced two new development contracts for Optimer binders and the agreement of licensing heads of terms with a global provider of specialty enzymes for developed enzyme-modulating Optimers.

From Aptamer Group 16 May 2025

Customized CRISPR gene editing therapy successfully treats infant with rare disease

In a historic medical breakthrough, a child diagnosed with a rare genetic disorder has been successfully treated with a customized CRISPR gene editing therapy by a team at Children's Hospital of Philadelphia (CHOP) and Penn Medicine.

15 May 2025

Study deciphers the role of histone deacetylases in lymphoma development

Lymphomas belong to the group of malignant diseases of the immune system and mainly affect the organs of the lymphatic system.

15 May 2025

Hyaluronidase-1 emerges as a key regulator of postmeal blood sugar

A recent study published in Life Metabolism has uncovered a surprising new player in the body's ability to regulate blood sugar after eating.

15 May 2025

Skin microbiome plays active role in sun protection and immune balance

The skin microbiome plays an important role in health and disease. Researchers have now substantiated that certain skin bacteria can protect us from the sun's ultraviolet (UV) radiation specifically by metabolizing cis-urocanic acid using an enzyme called urocanase.

13 May 2025

Targeting METTL3 may offer new hope for oral cancer treatment

A new research paper was published in Oncotarget, Volume 16, on May 8, 2025, titled "METTL3 promotes oral squamous cell carcinoma by regulating miR-146a-5p/SMAD4 axis."

11 May 2025

Obicetrapib slashes LDL cholesterol by over 30% in high-risk heart patients

A large multinational trial published in the New England Journal of Medicine shows that obicetrapib significantly lowers LDL cholesterol in high-risk cardiovascular patients. The CETP inhibitor also improved key lipid parameters with no major safety concerns, supporting its role in future combination therapies.

8 May 2025

Study identifies key enzyme linked to metastasis in head and neck cancer

A recent study published in Engineering has shed new light on the mechanisms underlying the metastasis of head and neck squamous cell carcinoma (HNSCC).

8 May 2025

Enzyme News and Research

Nanozymes offer promise for treating inflammation during pregnancy

Sucralose disrupts male fertility by damaging sperm and altering hormones in animal study

Red blood cells drive blood vessel damage in diabetes by exporting toxic vesicles

Zebrafish study reveals hidden dangers of environmental toxins from tires

EMA designates allopurinol as first orphan drug for the treatment of Marfan syndrome

USPSTF urges universal syphilis screening in pregnancy to prevent congenital infections

Newly discovered Cat1 protein halts viral infections by depleting cellular fuel

Long noncoding RNA ESSENCE identified as key driver of colorectal cancer progression

Electromagnetic waves disrupt SARS-CoV-2 spike protein and lower infectivity

Study reveals how acetaminophen may actually relieve pain

Extracellular vesicle detection moves forward with nanophotonic sensing and label-free imaging

Targeting PME-1 may offer new strategies for treating neurological disorders and cancer

Optimer licensing agreements and repeat custom

Customized CRISPR gene editing therapy successfully treats infant with rare disease

Study deciphers the role of histone deacetylases in lymphoma development

Hyaluronidase-1 emerges as a key regulator of postmeal blood sugar

Skin microbiome plays active role in sun protection and immune balance

Targeting METTL3 may offer new hope for oral cancer treatment

Obicetrapib slashes LDL cholesterol by over 30% in high-risk heart patients

Study identifies key enzyme linked to metastasis in head and neck cancer

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