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HER3 reemerges as a key driver of cancer progression and therapy resistance

A new publication shines a spotlight on HER3, a long-overlooked member of the ErbB receptor family, revealing its critical role in cancer progression and resistance to therapy.

12 May 2025

CAR-T cell therapy linked to brain fog in cancer patients

After treatment with CAR-T cells - immune cells engineered to attack cancer - patients sometimes tell their doctors they feel like they have "brain fog," or forgetfulness and difficulty concentrating.

12 May 2025

Blood-based biomarkers predict therapy failure in prostate cancer patients

New research has identified specific blood-based biomarkers that can predict the failure of prostate cancer treatment in both hormone-sensitive and castration-resistant patients.

12 May 2025

Tirzepatide outperforms semaglutide for weight loss in people without diabetes

A head-to-head trial found that tirzepatide led to significantly greater weight loss and waist reduction than semaglutide in adults with obesity but without diabetes. Over 72 weeks, tirzepatide helped more participants reach key weight loss milestones, with manageable side effects and strong metabolic benefits.

12 May 2025

Novel Alzheimer's therapy shows low risk of severe side effects

The Food and Drug Administration's approval in 2023 of lecanemab - a novel Alzheimer's therapy shown in clinical trials to modestly slow disease progression - was met with enthusiasm by many in the field as it represented the first medication of its kind able to influence the disease.

12 May 2025

Hearing aids may help older adults combat social isolation

Providing hearing aids and advice on their use may preserve social connections that often wane as we age, a new study shows.

12 May 2025

High school athletes with ADHD face extended recovery from concussions

When athletes who have attention-deficit/hyperactivity disorder get concussions, their ADHD disorder may prolong recovery, researchers think.

12 May 2025

Tirzepatide outperforms semaglutide in weight loss clinical trial

Tirzepatide (trade name Zepbound) promoted greater weight loss in individuals with obesity than did semaglutide (trade name Wegovy) in a clinical trial that compared the safety and efficacy of the injectable drugs.

12 May 2025

City of Hope opens largest outpatient facility to enhance cancer care

As advances in early detection and treatment transform cancer into a chronic disease, City of Hope, one of the largest and most advanced cancer research and treatment organizations in the U.S. with its National Medical Center named top 5 in the nation for cancer by U.S. News & World Report, opens its largest outpatient facility among its network of 38 U.S. locations.

12 May 2025

Millions of women may be unaware of their risk for cardiovascular-kidney-metabolic disease

Millions of women may be unknowingly living with risk factors for heart, kidney and metabolic disease – interconnected conditions that together drive risk for cardiovascular disease, the leading cause of death among women, according to experts with the American Heart Association, a global force changing the future of health for all.

12 May 2025

Effects of practice standards on opioid prescribing and chronic pain management

In an effort to curb misuse of opioids and prevent overdose deaths, the College of Physicians and Surgeons of British Columbia released a legally enforceable practice standard, Safe Prescribing of Drugs with Potential for Misuse/Diversion, in 2016.

12 May 2025

An Arm and a Leg: A health policy veteran puts 2025 in perspective

News has been coming out of Washington, D.C., since the start of the second Donald Trump administration like water out of a fire hose. It can feel impossible to stay on top of all the changes.

12 May 2025

PhoreMost makes key appointments to Board to advance development of next-generation degrader therapeutics

PhoreMost Ltd., a next-generation targeted protein degradation (TPD) company progressing a pipeline of degrader therapeutics within oncology and inflammation, today announced Barbara Duncan has joined its Board as Chair, and Stephen Dilly as Non-Executive Director.

From PhoreMost 12 May 2025

ELRIG announces keynote speakers for Drug Discovery 2025

ELRIG, a not-for-profit, volunteer-led organization dedicated to the global drug discovery community, has revealed the keynote speakers for its flagship event, Drug Discovery 2025. Taking place at the ACC in Liverpool, UK from 21-22 October, the conference will feature presentations from Professor Heather Pinkett (Northwestern University) and Dr Dafydd Owen (Pfizer Medicine Design).

From ELRIG (UK) Ltd. 12 May 2025

Australia faces critical medicine shortages amid global supply challenges

About 400 medicines are in short supply in Australia. Of these, about 30 are categorized as critical. These are ones with a life-threatening or serious impact on patients, and with no readily available substitutes.

12 May 2025

Vegetarians may need to watch thyroid health, especially with low iodine intake

Vegetarians had a modestly higher risk of developing hypothyroidism compared to high meat-eaters, but only after adjusting for BMI. No increased risk was seen for vegans or pescatarians in incident cases, though pescatarians showed a slight increase in baseline prevalence.

11 May 2025

Woman with rare genetic disorder delivers healthy baby after complex pregnancy

When Jessica Johnson, 36, began to experience labored breathing and heart palpitations, she quickly made an appointment to see a cardiologist.

11 May 2025

Time-restricted eating may be a promising strategy for sustaining long-term weight loss

Three months of time-restricted eating (TRE), irrespective of whether it is earlier or later in the day, may be a promising strategy for sustaining long-term weight loss in adults with overweight or obesity, according to preliminary results of a randomised controlled trial being presented at this year's European Congress on Obesity (ECO) in Malaga, Spain (11-14 May).

11 May 2025

New human ovaroid model offers insight into infertility and differences in sex development

A new model of tiny human ovary organoids, or ovaroids, has been developed from stem cells, according to research presented at the first Joint Congress between the European Society of Paediatric Endocrinology (ESPE) and the European Society of Endocrinology (ESE).

11 May 2025