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What are the current challenges and future directions of mRNA nanomedicine?

Researchers presented challenges related to the clinical translation of messenger ribonucleic acid (mRNA) technology, recent innovations and future directions to improve the clinical efficacy of mRNA nanomedicine.

15 Nov 2022

Five important things to know about polio

Public Health authorities have warned health care workers to be on the alert for polio, yet most physicians will not be familiar with presentation of this highly infectious, life-threatening disease.

15 Nov 2022

Do SSRIs lower the risk of long COVID?

Researchers conducted a retrospective study to determine whether SSRIs with immunomodulatory and antiplatelet properties can decrease the risk of post-acute sequelae of COVID-19 (PASC).

15 Nov 2022

Short-term outcomes in pregnant patients with COVID-19 who received nirmatrelvir–ritonavir treatment

Researchers investigated the short-term outcomes of treating pregnant patients exhibiting mild to moderate symptoms of COVID-19 with Paxlovid, which is a combination of the antivirals nirmatrelvir and ritonavir.

15 Nov 2022

Study points to a pathogenic role for compromised anti-SARS-CoV-2 responses in cerebrospinal fluid

Researchers used a high throughput systems serology method to compare serum and CSF samples from SARS-CoV-2 infected individuals with and without long COVID symptoms to determine changes in the SARS-CoV-2 humoral immune responses.

15 Nov 2022

What is the post-COVID-19-associated morbidity in German children, adolescents, and adults?

Researchers investigated coronavirus disease 2019 (COVID-19)-associated morbidity in children, adolescents, and adults using healthcare data covering ~46% of the German population.

14 Nov 2022

Study suggests the rapid expansion of naïve T cells can provide a fast and effective immune response to SARS-CoV-2 and other viral infections

Researchers investigated the early T cell responses during SARS-CoV-2 infections to understand the mechanisms of rapid clonal expansion that characterize the T cell responses to acute infections and vaccinations.

14 Nov 2022

SARS-CoV-2 detected in white-tailed deer in Canada

Researchers investigated the detection of SARS-CoV-2 in white-tailed deer.

14 Nov 2022

Cancer Research Horizons: The Innovation Engine of Cancer Research UK

Following ELRIG 2022, News-Medical speaks with Cancer Research Horizons, the innovation engine of Cancer Research UK about their efforts to advance the drug discovery sector.

From Cancer Research UK 14 Nov 2022

Survey assesses prevalence of H5N8 influenza in birds

The prevalence of the avian influenza H5N8 virus among birds and its pervasiveness based on geographical locations and time-point.

13 Nov 2022

Can monkeypox infection lead to myocarditis?

A recent study presents the first known case of myocarditis as a complication of monkeypox virus infection.

13 Nov 2022

Handheld diagnostic all-in-one lab kit could increase the speed and volume of disease testing

Using swarms of pinhead-sized magnets inside a handheld, all-in-one lab kit, UCLA researchers have developed a technology that could significantly increase the speed and volume of disease testing, while reducing the costs and usage of scarce supplies.

11 Nov 2022

Mouth ulcer as first sign of monkeypox virus infection

Recent infection with monkeypox virus can initially present with very few pronounced clinical symptoms and lacking signs of infection, and only few skin vesicles may be visible.

11 Nov 2022

What is the duration of persistent symptoms after SARS-CoV-2 infection, and what factors are associated with their resolution?

Researchers examined temporal dynamics of persistent symptom resolution following acute COVID-19 in the general population of France.

11 Nov 2022

Is placental antibody transfer after COVID-19 vaccination different from that after SARS-CoV-2 infection in pregnant individuals?

Researchers investigated the placental transfer ratios of anti-SARS-CoV-2 antibodies in pregnant females.

11 Nov 2022

People of all age groups are at risk of post-COVID-19 syndrome, study says

Following COVID-19 infection, there is significant new onset morbidity in children, adolescents and adults across 13 distinct diagnosis and symptom complexes, according to a new study publishing November 10th in the open access journal PLOS Medicine by Martin Roessler of Technische Universität Dresden, Germany, and colleagues.

10 Nov 2022

The spectrum of SARS-CoV-2–related neurologic involvement among children and adolescents in 2021

Researchers explored the distribution of severe neurologic involvement in SARS-CoV-2 pediatric patients.

10 Nov 2022

What is the role of adenoviruses in human health?

With advances in molecular biology informing recent developments in vaccinology, gene therapy, and other fields of medicine, human adenoviruses (HAdVs) have been of primary importance in medical research. A recent review looks at the promises of HAdVs, their potential dangers, and future challenges.

9 Nov 2022

Does fenofibrate improve clinical outcomes in patients with COVID-19?

Researchers assessed the effect of fenofibrate on acute COVID-19.

9 Nov 2022

The effect of vaccination-induced immunity on viral loads of SARS-CoV-2 Omicron variant

Researchers analyzed nationwide vaccination data and cycle threshold value data from four laboratories in Israel that conduct SARS-CoV-2 qRT-PCR tests to determine the effect of vaccination-induced immunity on the viral loads of the SARS-CoV-2 Omicron variant.

9 Nov 2022

Polymerase News and Research

What are the current challenges and future directions of mRNA nanomedicine?

Five important things to know about polio

Do SSRIs lower the risk of long COVID?

Short-term outcomes in pregnant patients with COVID-19 who received nirmatrelvir–ritonavir treatment

Study points to a pathogenic role for compromised anti-SARS-CoV-2 responses in cerebrospinal fluid

What is the post-COVID-19-associated morbidity in German children, adolescents, and adults?

Study suggests the rapid expansion of naïve T cells can provide a fast and effective immune response to SARS-CoV-2 and other viral infections

SARS-CoV-2 detected in white-tailed deer in Canada

Cancer Research Horizons: The Innovation Engine of Cancer Research UK

Survey assesses prevalence of H5N8 influenza in birds

Can monkeypox infection lead to myocarditis?

Handheld diagnostic all-in-one lab kit could increase the speed and volume of disease testing

Mouth ulcer as first sign of monkeypox virus infection

What is the duration of persistent symptoms after SARS-CoV-2 infection, and what factors are associated with their resolution?

Is placental antibody transfer after COVID-19 vaccination different from that after SARS-CoV-2 infection in pregnant individuals?

People of all age groups are at risk of post-COVID-19 syndrome, study says

The spectrum of SARS-CoV-2–related neurologic involvement among children and adolescents in 2021

What is the role of adenoviruses in human health?

Does fenofibrate improve clinical outcomes in patients with COVID-19?

The effect of vaccination-induced immunity on viral loads of SARS-CoV-2 Omicron variant

Discover how SciY empowers scientists

Why use light scattering to analyze proteins and viral vectors?

Changing the landscape of R&D to build clinical success from the ground up

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