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Ribonucleic acid (RNA) is a biologically important type of molecule that consists of a long chain of nucleotide units. Each nucleotide consists of a nitrogenous base, a ribose sugar, and a phosphate.

What happens when microplastics reach the testes? Study shows autophagy and cell loss

Researchers found that microplastics from everyday plastic tableware accumulate in human semen and, although not linked to semen quality in the full cohort, were associated with altered sperm parameters in specific subgroups. Experimental models confirmed that 50 nm polystyrene particles trigger autophagy and apoptosis via the FOXA1/MAP3K1/p38 pathway, impairing sperm structure and function.

15 Oct 2025

Astrocytes revealed as key players in stabilizing long-term emotional memories

Why are we able to recall only some of our past experiences? A new study led by Jun Nagai at the RIKEN Center for Brain Science in Japan has an answer.

15 Oct 2025

Ribosomal RNA found to share unique motifs with nervous system genes

Ribosomal RNA (rRNA) is a type of molecule and a key building block of the ribosome, the cell's protein-making machinery. rRNA accounts for much of the RNA in a cell, and it's crucial for life.

14 Oct 2025

Scientists revive diabetic beta cells, revealing a new path to restore insulin function

Researchers demonstrated that pancreatic β cells from type 2 diabetes donors can partially regain glucose responsiveness when cultured outside the diabetic environment. This recovery, driven by specific gene expression changes, identifies JAK inhibitors as potential therapeutic candidates to restore β-cell function.

14 Oct 2025

Living near Superfund sites increases risk of aggressive breast cancer

Women living close to federally designated Superfund sites are more likely to develop aggressive breast cancers - including the hard-to-treat triple-negative subtype - according to new studies from Sylvester Comprehensive Cancer Center, part of the University of Miami Miller School of Medicine.

10 Oct 2025

Discovery of unique brain cells sheds light on progressive multiple sclerosis

Scientists have identified an unusual type of brain cell that may play a vital role in progressive multiple sclerosis (MS), likely contributing to the persistent inflammation characteristic of the disease.

10 Oct 2025

Researchers develop AI system to decode the human immune system

Researchers explore the human immune system by looking at the active components, namely the various genes and cells involved.

9 Oct 2025

Engineered virus therapy triggers powerful immune responses in glioblastoma

A new study led by Break Through Cancer's Accelerating Glioblastoma (GBM) Therapies Through Serial Biopsies TeamLab has revealed that an engineered virus therapy, CAN-3110, triggered powerful immune responses deep inside glioblastoma tumors that were invisible to standard imaging like MRI, according to early analyses of two patients with recurrent GBM.

9 Oct 2025

Takara Bio USA, Inc. announces a series of updates to its spatial biology product portfolio, extending its innovation with a new class of spatial technology

Takara Bio USA, Inc. ("Takara Bio USA"), a wholly owned subsidiary of Takara Bio Inc. ("Takara Bio"), today announced a series of updates to its spatial biology product portfolio, extending its innovation with a new class of spatial technology.

9 Oct 2025

Research uncovers ASPL's critical role in stress granule life cycle

Stress granules are droplet-like protein hubs that temporarily shield fragile RNA from cellular stresses such as toxins. VCP is a protein essential for breaking up stress granules and has been linked to neurodegenerative diseases.

9 Oct 2025

Chiba University study clarifies molecular mechanism driving keloid's unpredictable growth

Keloids are raised, overgrown scars that can develop after skin injuries or surgery, often extending beyond the original wound boundaries. For many people, keloids are more than just a cosmetic concern; they often cause distressing symptoms such as chronic pain, itching, and restricted movement.

9 Oct 2025

Newly identified protein acts as a traffic controller for DNA replication

Mayo Clinic researchers have identified a protein that acts like a traffic controller for DNA, preventing damage during cell division - a discovery that could lead to new cancer therapies, according to a study published in Nature.

8 Oct 2025

Engineered CAR-NK cells show enhanced cancer killing and immune evasion

One of the newest weapons that scientists have developed against cancer is a type of engineered immune cell known as CAR-NK (natural killer) cells. Similar to CAR-T cells, these cells can be programmed to attack cancer cells.

8 Oct 2025

SMOC1 gene plays a surprising role in the development of type 2 diabetes

Scientists at City of Hope, one of the largest and most advanced cancer research and treatment organizations in the U.S., and a leading research center for diabetes and other life-threatening illnesses, have uncovered a gene called SMOC1 that plays a surprising role in the development of type 2 diabetes (T2D) by converting pancreatic cells that normally produce insulin into those that increase blood sugar.

7 Oct 2025

AI, omics, and systems biology could transform heart drug development

AI, omics, and systems biology can now help scientists design targeted drugs for cardiovascular disease pathways once thought "untreatable."

7 Oct 2025

Breakthrough in RNA-targeted drug discovery offers hope against viral diseases

In a quest to develop new antiviral drugs for COVID-19 and other diseases, a collaboration led by scientists at The Wertheim UF Scripps Institute has identified a potential new drug against the virus that causes COVID-19.

6 Oct 2025

New research reveals the cervix as a truly immunocompetent tissue

Cervical epithelial cells are far from passive bystanders in the body's immune system. New research shows they actually play an active and highly coordinated role in detecting and fighting infections. That's the conclusion of an international research team led by Associate Professor Cindrilla Chumduri from Aarhus University, and now published in the journal Science Advances.

6 Oct 2025

Study suggests spatial memory decline may be preventable and not universal

In the realm of memories, "where" holds special importance. Where did I leave my keys? Where did I eat dinner last night? Where did I first meet that friend? Recalling locations is necessary for daily life, yet spatial memory - which keeps track of "where" - is one of the first cognitive abilities to fade in old age. And deficits earlier in life can be a telltale sign of dementia.

3 Oct 2025

Deadly brain cancer erodes skull bone and alters immune marrow

Scientists at Montefiore Einstein Comprehensive Cancer Center (MECCC) and Albert Einstein College of Medicine have shown for the first time that glioblastoma-the deadliest form of brain cancer-affects not just the brain but also erodes the skull, alters the makeup of skull marrow, and interferes with the body's immune response.

3 Oct 2025

Elderberry juice boosts key genes for metabolic flexibility in overweight adults

Elderberry juice intake triggers metabolic gene expression changes, enhancing glucose control and fat oxidation in overweight adults during meal challenges.

3 Oct 2025