immunity News and Research

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Proteomic study reveals new drug targets in gastric signet ring cell carcinoma

Gastric signet ring cell carcinoma (GSRCC) is a distinct subtype of gastric cancer (GC) with unique epidemiological and pathogenic characteristics.

29 Aug 2025

Researchers identify genetic toolkit to reprogram cells into immune sentinels

An international team led by researchers at Lund University in Sweden has identified the molecular tools needed to reprogram ordinary cells into specialized immune cells.

29 Aug 2025

Glycosylation emerges as a key player in kidney disease progression

Kidney diseases affect nearly 700 million people worldwide and are a growing cause of mortality and health care costs.

29 Aug 2025

Sharp rise in pertussis hospitalizations highlights need for timely vaccination

Pertussis, commonly known as whooping cough, is a vaccine-preventable disease which continues to circulate even in areas where vaccination coverage is high, and outbreaks may still occur. A study published in Eurosurveillance and conducted at Meyer Children's Hospital in Florence, Italy, has found a sharp increase in hospitalisations for pertussis among children and adolescents (patients aged 16 years or under) in 2024.

29 Aug 2025

Gut disorders forecast Alzheimer’s and Parkinson’s risk years before diagnosis

Study maps clinical, genetic, and proteomic links between gut-brain disorders and neurodegeneration, showing how diabetes, vitamin D deficiency, and bowel disorders forecast Alzheimer’s and Parkinson’s years in advance. Multimodal models in biobanks highlight early detection and personalized prevention opportunities.

28 Aug 2025

New NIH-funded project aims to turn rare HIV cures into broadly applicable immunotherapy

Nearly 20 years ago, a man named Timothy Ray Brown who was living with HIV and cancer, underwent two courses of stem cell transplantation to treat his acute myeloid leukemia.

28 Aug 2025

Longitudinal study reveals how GLP-2 analog therapy transforms the intestinal environment

Researchers from Japan discover that glucagon-like peptide-2 (GLP-2) analogs can deeply and beneficially reshape the intestinal environment.

27 Aug 2025

Columbia study urges federal recognition of public health nurses

After 140 years of vital, often invisible service, public health nurses (PHNs) deserve formal recognition as a distinct occupation, says a new study from Columbia University Mailman School of Public Health.

27 Aug 2025

Targeting gut signaling protein may protect against alcohol-related liver damage

Alcohol-associated liver disease (ALD) is a major cause of liver transplantation and death worldwide, and its impact is only growing. In 2022, the annual cost of ALD in the United States was $31 billion.

27 Aug 2025

How shifting mindsets after catastrophes can promote mental and physical health

Catastrophes, by definition, are devastating, but they can often be catalysts for lasting, positive change – and if people can adopt that perspective, they may see some real benefits, a Stanford-led study suggests.

26 Aug 2025

Antibiotics in pregnancy and infancy do not raise autoimmune disease risk in children

A nationwide Korean cohort study found that antibiotic use during pregnancy or early infancy did not increase overall risk of childhood autoimmune diseases. Subgroup signals for Crohn’s disease and autoimmune thyroiditis warrant cautious follow-up.

25 Aug 2025

Researchers discover why smoking tobacco helps people with ulcerative colitis

Researchers led by Hiroshi Ohno at the RIKEN Center for Integrative Medical Sciences (IMS) in Japan have discovered why smoking tobacco helps people suffering from ulcerative colitis, a chronic disease typified by inflammation of the large intestine.

25 Aug 2025

Next-gen sequencing reveals the regulatory potential of the non-coding genome

The non-coding genome, once dismissed as "junk DNA", is now recognized as a fundamental regulator of gene expression and a key player in understanding complex diseases. Following the landmark achievements of the Human Genome Project (HGP), scientists have increasingly focused on deciphering the non-coding regions of the human genome, which comprise approximately 98% of the genetic material.

23 Aug 2025

SOX2 drives progression and therapy resistance in advanced prostate cancer

Prostate cancer remains a global health challenge, ranking as the second most common malignancy among men.

22 Aug 2025

CHI3L1 emerges as a powerful biomarker for liver disease diagnosis and management

The identification of Chitinase-3-like protein 1 (CHI3L1) as a crucial biomarker in liver disease is revolutionizing how clinicians approach the diagnosis, monitoring, and treatment of various liver conditions.

22 Aug 2025

New method enables comprehensive analysis of metabolites in biological samples

Researchers from the McCullagh Group in Oxford University's Department of Chemistry have published an innovative method in Nature Protocols today (22 August) that provides comprehensive analysis of metabolites found in cells, tissues and biofluids.

22 Aug 2025

Gut bacteria in mothers and newborns may shape infants’ risk of early respiratory infections

Finnish researchers found that differences in maternal and infant gut microbiota during the first weeks of life were linked to the risk of respiratory tract infections in the first six months. Specific bacteria, including butyrate producers and opportunistic pathogens, may shape early infection susceptibility.

21 Aug 2025