Autoimmunity News and Research

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Autoimmune Disease is a condition in which the body recognizes its own tissues as foreign and directs an immune response against them.

New blood atlas reveals how diseases leave unique protein signatures

A new study has mapped the distinct molecular "fingerprints" that 59 diseases leave in an individual's blood protein – which would enable blood tests to discern troubling signs from those that are more common.

9 Oct 2025

Discovery of vascular-associated fibroblastic cells opens new path for diabetes treatment

Type 1 diabetes is an autoimmune disease in which the immune system mistakenly attacks the cells that produce insulin-a critical hormone that regulates blood sugar in the body.

8 Oct 2025

Targeting TGF-β signaling as a strategy to treat liver fibrosis

Liver fibrosis, a pathological scarring process resulting from chronic liver injury, represents a significant global health burden due to its potential progression to cirrhosis and hepatocellular carcinoma.

25 Sep 2025

Scientists outline how future therapies could change type 1 diabetes care

Researchers writing in The Lancet review breakthroughs in type 1 diabetes treatment, from immunotherapies that delay onset to stem-cell β-cell replacement and automated insulin delivery. They stress that equitable access, validated surrogate endpoints, and scalable technologies are crucial for lasting impact.

24 Sep 2025

Blocking immune brake protein boosts defense against Aspergillus fumigatus

People are exposed to millions of fungal spores every day, even potentially harmful ones like those from Aspergillus fumigatus.

11 Sep 2025

Fasting supports type 1 diabetes care by reshaping the microbiome

A week of fasting alters the gut microbiome in type 1 diabetes, aligning it with healthy profiles and enhancing cholesterol and weight management.

20 Aug 2025

Mayo Clinic identifies cellular 'fountain of youth' in aging immune systems

The immune system is meant to protect the body from infection and disease. But with age, it can become less capable of doing so.

14 Aug 2025

Parasitic worm evades detection by suppressing skin neurons

New research, published in The Journal of Immunology, discovered that a parasitic worm suppresses neurons in the skin to evade detection.

11 Aug 2025

Forever chemicals cross placenta and breast milk affecting babies’ immunity

New research reveals that tiny amounts of PFAS-widely known as "forever chemicals"-cross the placenta and breast milk to alter infants' developing immune systems, potentially leaving lasting imprints on their ability to fight disease.

23 Jul 2025

New monoclonal antibody enhances immune response by selectively targeting Tregs

A new research paper was published in Volume 16 of Oncotarget on July 9, 2025, titled "A novel anti-human CD25 mAb with preferential reactivity to activated T regulatory cells depletes them from the tumor microenvironment."

17 Jul 2025

UCLA researchers discover new way to prevent immunotherapy-induced type 1 diabetes

A team of researchers at the UCLA Health Jonsson Comprehensive Cancer Center has identified a potential new strategy to prevent, and even reverse, immune checkpoint inhibitor–induced type 1 diabetes, a rare but life-threatening side effect of cancer immunotherapy, using an existing class of autoimmune drugs.

8 Jul 2025

Innovative bispecific antibody targets LAG-3 to treat autoimmune diseases

Immune checkpoint pathways regulate T cell function and play pivotal roles in the treatment of both cancer and autoimmune diseases.

7 Jul 2025

Breakthrough study questions longstanding STING activation approach

Researchers have long focused on the STING (Stimulator of Interferon Genes) pathway as a way to harness the immune system's natural defenses against cancer.

3 Jul 2025

Engineered protein silences harmful T cells in autoimmune disease

An engineered protein turns off the kind of immune cells most likely to damage tissue as part of Type-1 diabetes, hepatitis, multiple sclerosis, shows a new study in mice.

1 Jul 2025

Study finds nearly double risk of depression and anxiety in autoimmune patients

Living with an autoimmune disease is linked to a near doubling in the risk of persistent mental health issues, such as depression, generalised anxiety, and bipolar disorder, with these risks higher in women than in men, finds a large population-based UK study, published in the open access journal BMJ Mental Health.

25 Jun 2025

Endometriosis linked to higher odds of autoimmune conditions

New research links endometriosis to autoimmune diseases, revealing shared mechanisms that may lead to earlier diagnosis and targeted treatments for patients.

23 Jun 2025

T cells play key role in early stages of Parkinson’s disease

Your T cells work hard to fight disease. Unfortunately, "friendly fire" from T cells can sometimes harm the body's healthy tissues.

19 Jun 2025

CAR T-cell therapy successfully treats rare autoimmune disease of the peripheral nervous system

Physicians from Bochum have used a cancer treatment method to treat severe autoimmune diseases.

18 Jun 2025

OCCAM Immune and Cancer Research Institute join forces to advance immunotherapy

In a new collaboration that could transform how cancer is treated, OCCAM Immune-a Mount Sinai initiative focused on understanding the immune system's role in disease-is partnering with the Cancer Research Institute (CRI) to unlock the secrets of how the immune system responds to advanced therapies.

17 Jun 2025

Higher BMI, not menopause age, increases hypothyroidism risk

Researchers analyzed over 15,000 postmenopausal Canadian women to investigate whether age at natural menopause influences the risk of developing overt hypothyroidism. The study found no association, but higher BMI was linked to increased hypothyroidism risk.

29 May 2025