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Patient-derived organoids advance cancer therapy and vaccines

Tiny, three-dimensional organoid models are reshaping cancer research by recreating the intricate architecture and diversity of human tumors.

25 Sep 2025

Organophosphate pesticide exposure linked to reduced sperm quality in healthy men

This pilot study found that urinary metabolites of organophosphate pesticides were linked to reduced sperm motility in healthy young men, though results were preliminary. Oxidative stress did not explain the association, suggesting other biological pathways may be involved.

25 Sep 2025

New $10 million initiative aims to tailor diets for Canadians living with IBD

Over 300,000 Canadians live with chronic inflammatory bowel diseases (IBD), including Crohn's and ulcerative colitis.

23 Sep 2025

New screening method boosts efficiency and accuracy of CAST genome editing

Natural systems such as CRISPR-associated transposons (CASTs) offer a targetable, one-step way to edit genomes.

23 Sep 2025

New imaging technique enhances live-cell visualization in standard lab setups

Optical diffraction tomography (ODT) has long been recognized for its potential in non-invasive, label-free imaging of live biological cells. However, a major challenge arises when ODT is applied to standard multi-well cell culture plates, a common tool use under realistic laboratory conditions for biological studies.

16 Sep 2025

Sapio Sciences and Ultima Genomics partner to advance multi-omics research

Sapio Sciences, the science-aware™ lab informatics platform, today announced a strategic partnership with Ultima Genomics.

From Sapio Sciences 10 Sep 2025

Axxam and B'SYS partner to expand access to validated ion channel cell lines for high-throughput electrophysiology

Axxam S.p.A., a premier provider of integrated early drug discovery services, and B'SYS GmbH, a specialist in ion channel biology, are pleased to announce a strategic collaboration focused on enabling access to validated ion channel cell lines for hit and lead identification through high-throughput electrophysiological screening.

From Axxam S.p.A 8 Sep 2025

Breakthrough technology enables faster and cheaper antibody analysis

Antibodies are the critical targeting agents of the immune system and the crux of immune therapy and vaccine development, but studying them is slow, expensive and labor-intensive.

4 Sep 2025

Beckman Coulter Life Sciences and HSE•AG partner to revolutionize nucleic acid quantification and purification through liquid handling

Beckman Coulter Life Sciences, a Danaher company and global leader in laboratory automation and innovation, is redefining nucleic acid quantification through a strategic collaboration with Hombrechtikon Systems Engineering•AG (HSE•AG), a Swiss provider of customized automation and engineering solutions for the life sciences and diagnostics sectors.

From Beckman Coulter Life Sciences 4 Sep 2025

Preventative maintenance programs from INTEGRA Biosciences help labs reduce downtime and extend equipment lifespans

INTEGRA Biosciences is helping laboratories to maintain peak instrument performance and avoid unexpected disruptions with its preventative maintenance programs.

3 Sep 2025

Beetroot juice lowers blood pressure in older adults by reshaping oral bacteria

Dietary nitrate from beetroot juice lowered blood pressure in older adults but not in younger participants in a double-blind crossover trial. The effect was linked to oral microbiome changes, including reduced Prevotella and higher plasma nitrite, without improvements in endothelial function

2 Sep 2025

Single-cell transcriptomics reveals new players in liver regeneration

The liver is remarkable for its ability to regenerate after injury, yet when this process fails, acute liver failure (ALF) carries devastating outcomes.

2 Sep 2025

BindCraft reimagines protein binder discovery through structural prediction

Physical interactions between proteins influence anything from cell signaling and growth to immune responses, so the ability to control these interactions is of great interest to biologists.

29 Aug 2025

Inherited DNA changes can cause hormone imbalance in women with polycystic ovary syndrome

Increased testosterone levels are a consistent hormonal abnormality in women with polycystic ovary syndrome (PCOS). This study identified specific DNA variants in the gene DENND1A, which increase testosterone production in PCOS.

29 Aug 2025

Aptamer Group introduces novel biomarker discovery service

Aptamer Group plc, the leading developer of next-generation synthetic binders delivering innovation to the life science industry, today announced the launch of its biomarker discovery service, offering researchers in pharmaceutical, biotechnology, and diagnostic development an innovative approach to identify and validate new disease markers.

28 Aug 2025

AUF1 protein shown to suppress cellular senescence and altered metabolism

A new research paper was published in Volume 17, Issue 7 of Aging (Aging-US) on July 24, 2025, titled "RNA-binding protein AUF1 suppresses cellular senescence and glycolysis by targeting PDP2 and PGAM1 mRNAs."

27 Aug 2025

Redefining peptide synthesis with Vapourtec

Vapourtec's Peptide-Builder, a fully automated, high-throughput benchtop peptide synthesizer, has been designed to redefine solid-phase peptide synthesis (SPPS). Compact, efficient and intuitive, it brings a new level of simplicity and performance to peptide synthesis.

27 Aug 2025

New method uncovers how extracellular vesicles impact immune response in cancer

Certain types of biochemical processes can impair the immune system's ability to recognize and kill cancer cells. Purdue University's W. Andy Tao and his associates have developed a new way to study these processes.

26 Aug 2025

iconPCR™: Powering the next wave of metagenomics and microbiome discovery

The landscape of metagenomics and microbiome research is evolving at breakneck speed. As sequencing technologies improve and the demand for high-resolution, bias-free microbial data grows, the bottleneck is shifting from sequencing itself to the quality of upstream sample preparation.

From n6 23 Aug 2025

Next-gen sequencing reveals the regulatory potential of the non-coding genome

The non-coding genome, once dismissed as "junk DNA", is now recognized as a fundamental regulator of gene expression and a key player in understanding complex diseases. Following the landmark achievements of the Human Genome Project (HGP), scientists have increasingly focused on deciphering the non-coding regions of the human genome, which comprise approximately 98% of the genetic material.

23 Aug 2025