Lipoprotein News and Research

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A lipoprotein is a biochemical assembly that contains both proteins and lipids. The lipids or their derivatives may be covalently or non-covalently bound to the proteins.

New guidelines urge earlier cholesterol treatment to prevent heart disease

Doctors should consider treating high cholesterol much earlier and more aggressively than they have in the past, according to a new perspective by Weill Cornell Medicine, NewYork-Presbyterian and Yale School of Medicine investigators.

19 May 2026

Healthy plant-based foods may improve pregnancy cardiometabolic markers

Higher-quality plant-based diets were associated with more favorable cardiometabolic biomarkers in pregnant U.S. women, especially higher HDL-C and lower TG/HDL-C ratio. Indices that emphasized healthy plant foods, rather than simply penalizing animal foods, showed the strongest links with insulin resistance and lipid markers.

15 May 2026

Urges for cardiologists to screen patients for UPF intake

The European Society of Cardiology identifies ultra-processed foods as a key cardiovascular risk, urging a shift in dietary guidelines for better heart health.

11 May 2026

Blood tests years before pregnancy predict risk of hypertension

Pre-pregnancy blood biomarkers linked to hypertension risk highlight the potential for early intervention in managing hypertensive disorders of pregnancy.

5 May 2026

New genetic risk report reveals hidden heart disease risk before symptoms appear

Researchers developed and externally validated integrated polygenic risk scores for eight cardiovascular conditions using large U.S.-based biobank data. The clinically orderable report may help identify inherited cardiovascular risk that traditional clinical markers can miss, although broader prospective validation is still needed.

30 Apr 2026

New genetic risk test estimates inherited risk for cardiovascular conditions

Researchers at Mass General Brigham Heart and Vascular Institute and collaborators have developed and validated a new genetic risk test that can estimate a person's inherited risk for eight common cardiovascular conditions, offering a more comprehensive approach to prevention.

29 Apr 2026

Study suggests a U-shaped link between cholesterol levels and mortality among Chinese adults

A new commentary published in Engineering highlights key findings from a large multinational cohort study that re-evaluates cholesterol management for cardiovascular and chronic disease prevention, suggesting a U-shaped association between cholesterol levels and mortality among Chinese adults that challenges the conventional "lower is better" approach.

28 Apr 2026

Yoga to help manage obesity-related heart and metabolic risks

The impact of yoga on heart health in obesity is modest, suggesting it as a complementary approach for improving metabolic outcomes in high BMI populations.

27 Apr 2026

Scientists will probe whether processing itself makes ultra-processed foods harmful

A randomized controlled trial protocol will test whether the cardiometabolic risks linked to ultra-processed foods stem from industrial processing, poor nutrient composition, or both. Using four controlled diets, researchers will separate the effects of UPF content from saturated fat, added sugar, and sodium on LDL cholesterol, insulin resistance, and blood pressure.

26 Apr 2026

Elevated Lp(a) levels associated with residual cardiovascular risk

New data analyzing more than 20,000 patients from three major NIH studies show that elevated Lipoprotein(a) [Lp(a)] is associated with residual cardiovascular risk and warrants aggressive risk reduction.

24 Apr 2026

Low-plastic diets cut plastic-linked chemicals in urine within 7 days, study finds

A Nature Medicine study found that healthy Australian adults were widely exposed to plastic-associated chemicals, with processed, packaged, and canned foods emerging as important modifiable contributors to urinary phthalate and bisphenol levels. In a 7-day pilot randomized trial, low-plastic food interventions reduced several urinary plastic-associated chemicals without lowering daily energy intake.

22 Apr 2026

Prediabetes leaves lasting fat tissue changes after bariatric surgery

Prediabetes may leave a lasting molecular "footprint" on adipose (fat) tissue which appears to make maintaining weight loss after bariatric surgery more difficult, according to new research being presented at this year's European Congress on Obesity (ECO) in Istanbul, Turkey (12-15 May).

22 Apr 2026

Why heart risk is hard to predict in type 1 diabetes

A European study reveals cardiovascular risk patterns in type 1 diabetes, highlighting the need for tailored prevention strategies to catch complications early.

20 Apr 2026

Eating oranges daily may shift lipid patterns in fatty liver disease

A 4-week trial on 'Navelina' oranges shows potential effects on lipid metabolism in fatty liver disease, revealing intriguing but non-significant patterns.

20 Apr 2026

Metabolic syndrome doubles worldwide over two decades

A global study reveals a sharp rise in metabolic syndrome prevalence from 2000 to 2023, highlighting urgent public health challenges and regional disparities.

15 Apr 2026

Obesity health risks differ significantly between men and women

New research being presented at this year's European Congress on Obesity (ECO) in Istanbul, Turkey (12-15 May), reveals distinct patterns of heart, metabolic, and inflammatory health risks between men and women living with obesity, providing an insight into how clinicians may be able to tailor management approaches.

13 Apr 2026

Challenging processed meat risks for dry-cured ham consumption

The effects of dry-cured ham on cardiometabolic health are nuanced, with evidence suggesting it may not adversely affect key health markers in moderation.

7 Apr 2026

Evolocumab trial could reshape how doctors treat high-risk cholesterol patients

A new ACC/AHA dyslipidemia guideline and editorial argue that guideline development is rigorous but can lag behind fast-moving science, using the VESALIUS-CV trial as a clear example. The trial showed that intensive LDL cholesterol lowering with evolocumab reduced cardiovascular events in high-risk patients without prior heart attack or stroke, with implications for future guideline updates.

6 Apr 2026

Imaging study measures pancreatic fat in children and teens

Higher fat content in the pancreas of children and adolescents with obesity is associated with an increased level of heart and metabolic risk factors, including higher than average body mass index (BMI), elevated diastolic blood pressure, higher levels of abdominal and liver fat, and insulin resistance, according to new research presented at this year's European Congress on Obesity (ECO) in Istanbul, Turkey (12-15 May).

1 Apr 2026

What happens when more of your exercise is vigorous instead of moderate?

In a large UK Biobank analysis, a higher proportion of vigorous physical activity relative to total activity volume was associated with lower risks of eight major chronic diseases and all-cause mortality, even after accounting for overall activity volume. Device-based data suggested that activity intensity generally offered greater preventive potential than total volume alone across most outcomes.

31 Mar 2026