Nanoparticle News and Research

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In nanotechnology, a particle is defined as a small object that behaves as a whole unit in terms of its transport and properties. It is further classified according to size: in terms of diameter, fine particles cover a range between 100 and 2500 nanometers, while ultrafine particles, on the other hand, are sized between 1 and 100 nanometers.

Microneedle nanoparticle platform improves lymphatic imaging with high resolution

The lymphatic system plays a critical role in pathological conditions such as lymphedema and chronic inflammation to tumor metastasis, venous insufficiency, and impaired wound healing, making accurate evaluation of its structure and function increasingly important.

13 Apr 2026

Non-clinical safety assessment crucial for CRISPR-based gene therapies

The rapid evolution of CRISPR/Cas genome editing has redefined the possibilities of cellular and gene therapy, enabling precise correction, disruption, and regulation of disease-associated genes.

10 Apr 2026

Microplastics found in human bile may be associated with gallstones

Findings show microplastics in bile may trigger cellular senescence, suggesting a link to gallstone disease and highlighting the need for further research.

9 Apr 2026

New 3D printing method delivers cancer drugs directly to tumors

University of Mississippi research offers hope that cancer drug therapies packaged in 3D-printed carriers could deliver medication directly to tumors while reducing many of the side effects that cancer patients endure.

6 Apr 2026

Reusable antimicrobial masks shed toxic metals during washing

Study shows reusable masks may leach harmful metals into aquatic environments, emphasizing the environmental risks of metal nanoparticles in manufacturing.

1 Apr 2026

Lipid nanoparticles help CAR T cells melt pancreatic cancer barriers

Often diagnosed when surgery is no longer an option, pancreatic cancer is one of the most difficult cancers to treat and has one of the lowest rates of survival among major malignancies.

31 Mar 2026

New nanoparticle system boosts scalable production of therapeutic exosomes

Researchers from Xi'an Jiaotong-Liverpool University (XJTLU) in China have developed a streamlined process that makes it easier to produce tiny therapeutic particles released by cells, called exosomes, which are being explored as a new type of medical treatment.

24 Mar 2026

Redesigned lipid nanoparticles improve mRNA delivery to lymph nodes

Penn Engineers have redesigned a key component of lipid nanoparticles (LNPs), the delivery vehicles behind mRNA vaccines, to steer the particles toward lymph nodes while reducing off-target delivery to the liver.

24 Mar 2026

New nanomaterial enhances bioimaging and targeted cancer drug delivery

The Nanomedicine and Nanotoxicology Group (GNano) at the University of São Paulo's São Carlos Institute of Physics (IFSC-USP) in Brazil has discovered a way to transform hydroxyapatite, a bioceramic material, into a nanoparticle with enhanced intrinsic luminescence.

18 Mar 2026

New nanoparticle therapy overcomes T cell exhaustion in solid tumors

Engineers at the University of Pennsylvania have developed a new type of lipid nanoparticle (LNP) that could one day serve as a universal immunotherapy for cancers that form solid tumors, including common variants such as cancers of the breast, liver and colon.

18 Mar 2026

Modified lipid nanoparticles boost mRNA vaccines while reducing side effects

The most common side effects of mRNA vaccines like the COVID-19 shot are well known: soreness, mild fever and general malaise.

17 Mar 2026

Adding three simple amino acids boosts mRNA and CRISPR delivery

Lipid nanoparticles, or LNPs, best known as the delivery vehicle for the COVID-19 mRNA vaccines received by billions of people, are now at the center of a much larger medical revolution.

12 Mar 2026

Simplified nanoparticles "educate" the immune system to find and destroy disease-causing cells

Johns Hopkins Medicine scientists say they have developed a simplified version of biodegradable nanoparticles that can "educate" the immune system to find and destroy disease-causing cells throughout the body.

11 Mar 2026

DNA-based barcoding reveals which nanoparticles successfully deliver genetic therapies

Drug delivery researchers have vastly improved the potential of genetic therapies by overcoming the challenge of consistently getting genes and gene-editing tools where they need to be within cells.

11 Mar 2026

DNA origami vaccine platform shows promise against multiple infectious viruses

The COVID-19 pandemic brought messenger RNA (mRNA) vaccines to the forefront of global health care. After their clinical trial stages, the first COVID-19 mRNA vaccine was administered on 8 December 2020 and mathematical models suggest that mRNA vaccines prevented at least 14.4 million deaths from COVID-19 in the first year alone.

11 Mar 2026

Targeting IGF2BP2 improves anti-angiogenic therapy effectiveness in colorectal cancer

A recent study published in Engineering has shed light on a novel therapeutic target for improving anti-angiogenic treatment in colorectal cancer (CRC).

10 Mar 2026

Study reveals hydration energetics as key to nanoparticle performance in medicine

Researchers at Arizona State University have uncovered a key scientific principle that governs how what's coated on the surfaces of engineered nanoparticles may ultimately control how they work in our bodies.

2 Mar 2026

Fe₃O₄@mPEG-Ag nanoparticles offer non-antibiotic strategy to combat drug-resistant bacteria

A collaborative study by Guangzhou Medical University and South China University of Technology, published in BME Frontiers, introduces Fe₃O₄@mPEG-Ag nanoparticles (NPs) as a groundbreaking non-antibiotic strategy to combat drug-resistant bacteria.

27 Feb 2026

New review explains how circular RNAs could unlock fat browning therapies

A Cell Death & Disease review synthesizes preclinical evidence that circular RNAs regulate adipose browning and metabolic pathways through microRNA interactions, protein binding, and organelle-linked stress mechanisms. It highlights their biomarker and therapeutic potential in obesity and type 2 diabetes while underscoring key translational challenges, including delivery specificity and human validation.

26 Feb 2026

Disordered lipid nanoparticles enhance RNA delivery efficiency

The tiny fatty capsules that delivered COVID-19 mRNA vaccines into billions of arms may work better when they're a little disorganized.

22 Feb 2026

Nanoparticle News and Research

Further Reading

Microneedle nanoparticle platform improves lymphatic imaging with high resolution

Non-clinical safety assessment crucial for CRISPR-based gene therapies

Microplastics found in human bile may be associated with gallstones

New 3D printing method delivers cancer drugs directly to tumors

Reusable antimicrobial masks shed toxic metals during washing

Lipid nanoparticles help CAR T cells melt pancreatic cancer barriers

New nanoparticle system boosts scalable production of therapeutic exosomes

Redesigned lipid nanoparticles improve mRNA delivery to lymph nodes

New nanomaterial enhances bioimaging and targeted cancer drug delivery

New nanoparticle therapy overcomes T cell exhaustion in solid tumors

Modified lipid nanoparticles boost mRNA vaccines while reducing side effects

Adding three simple amino acids boosts mRNA and CRISPR delivery

Simplified nanoparticles "educate" the immune system to find and destroy disease-causing cells

DNA-based barcoding reveals which nanoparticles successfully deliver genetic therapies

DNA origami vaccine platform shows promise against multiple infectious viruses

Targeting IGF2BP2 improves anti-angiogenic therapy effectiveness in colorectal cancer

Study reveals hydration energetics as key to nanoparticle performance in medicine

Fe₃O₄@mPEG-Ag nanoparticles offer non-antibiotic strategy to combat drug-resistant bacteria

New review explains how circular RNAs could unlock fat browning therapies

Disordered lipid nanoparticles enhance RNA delivery efficiency

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