in vivo News and Research

RSS

Dietary zinc may reduce plasmid transfer in gut microbes

Genes responsible for antimicrobial resistance (AMR) can spread from microbe to microbe through circular genetic material called plasmids, and this lateral transfer occurs in the gut.

3 Oct 2024

Researchers boost natural defenses to fight cataracts and delay the need for surgery

Researchers have reviewed strategies to increase glutathione levels in the eye lens, focusing on endogenous molecular mechanisms to prevent cataracts by countering oxidative stress.

3 Oct 2024

Researchers develop technology to change protein identity in vivo

Researchers at the RIKEN Cluster for Pioneering Research (CPR) have developed technology that can alter, within the body, the recognized identity of proteins. The innovation, published in Nature Communications on October 2, allowed researchers to target mouse tumors with a protein and then transport that protein out of the body.

3 Oct 2024

Scientists unveil a 3D photoacoustic scanner that speeds up vascular imaging for real-time clinical use

Researchers have developed a rapid 3D photoacoustic tomography (PAT) scanner for high-resolution vascular imaging, enabling fast and detailed visualization of the microvasculature.

1 Oct 2024

Future directions and challenges in harnessing NK cells against Acute Myeloid Leukemia

Acute Myeloid Leukemia (AML) remains one of the most challenging hematological malignancies to treat, with relapse and refractory cases continuing to pose significant hurdles

1 Oct 2024

Novel lipid nanoparticles enhance tissue-specific drug delivery

Penn Engineers have discovered a novel means of directing lipid nanoparticles (LNPs), the revolutionary molecules that delivered the COVID-19 vaccines, to target specific tissues, presaging a new era in personalized medicine and gene therapy.

1 Oct 2024

Traditional Chinese medicine shows potential in cancer treatment

Cancer, a pervasive global health concern, remains a leading cause of mortality worldwide. Current cancer treatment modalities encompass surgery, radiotherapy, chemotherapy, immunotherapy, and targeted therapy, all of which have significantly contributed to improving patient survival.

1 Oct 2024

SWIR fluorescence imaging enhances visualization of lymphatic vessels

The lymphatic system, the body's second largest circulatory network, plays a crucial role in maintaining fluid balance and immune function.

30 Sep 2024

Discovery of antibodies that boost complement activation against K. pneumoniae

Researchers investigate antibody-dependent complement activation during Klebsiella pneumoniae infection.

30 Sep 2024

Brusatol may serve as potential adjuvant therapy for pancreatic ductal adenocarcinoma

Announcing a new publication for Acta Materia Medica journal. Chemoresistance to gemcitabine (Gem) remains a substantial obstacle in the treatment of pancreatic ductal adenocarcinoma carcinoma (PDAC).

29 Sep 2024

Perceived stress can directly trigger psoriasis relapse

Innovative research has provided compelling evidence that perceived stress can directly trigger the relapse of psoriatic skin lesions. The study, presented today at the European Academy of Dermatology and Venereology (EADV) Congress 2024, is the first to scientifically validate this connection in vivo.

26 Sep 2024

Innovative CAR-T cells effectively target glioblastoma with reduced toxicity

Glioblastoma is the most common and most aggressive primary brain tumor, with an average survival after diagnosis of less than two years, and against which current treatments remain ineffective.

26 Sep 2024

Multi-omics analysis reveals mechanism of action for ruthenium-based anti-cancer agent

This study is led by Prof. Cai-Ping Tan, Prof. Zong-Wan Mao (MOE Key Laboratory of Bioinorganic and Synthetic Chemistry, School of Chemistry, Sun Yat-Sen University) and Prof. Zheng-Qiu Li (School of Pharmacy, MOE Key Laboratory of Tumor Molecular Biology, Jinan University).

26 Sep 2024

Understanding SARS-CoV-2's viral strategies for infection

This new article publication from Acta Pharmaceutica Sinica B, discusses how SARS-CoV-2 ORF10 hijacking ubiquitination machinery reveals potential unique drug targeting sites.

26 Sep 2024

Chemical genetics uncovers promising anti-COVID compounds

This new article publication from Acta Pharmaceutica Sinica B, discusses the identification of novel small-molecule inhibitors of SARS-CoV-2 by chemical genetics.

25 Sep 2024

Optimized nanoadjuvants enhance in situ tumor vaccine for ovarian cancer

This new article publication from Acta Pharmaceutica Sinica B, discusses how molecular glue triggers degradation of PHGDH by enhancing the interaction between DDB1 and PHGDH.

25 Sep 2024

Researchers gain new understanding of how immune cells respond to heat during fever

The study reveals that moderate fever enhances CD4 T cell activity while reducing regulatory T cell suppression, highlighting temperature's immune effects.

25 Sep 2024

Microbial biomarkers identified in lupus and IBD offer pathways for targeted therapies

Research connects gut microbiota to lupus and IBD, uncovering microbial markers and pathways that could inform targeted therapies for autoimmune disorders.

24 Sep 2024

New roadmap to advance UK’s bioelectronics for healthcare through materials innovation

The Henry Royce Institute has published the Materials for Bioelectronics in Healthcare Strategy and Action Plan a comprehensive report that aims to help future-proof the UK’s bioelectronics for healthcare sector through materials innovation.

24 Sep 2024

Neuroactive drugs show promising anti-glioblastoma effects in preclinical trials

Study explores the potential to repurpose neuroactive drugs, originally approved for neurological disorders, for the treatment of glioblastoma. Vortioxetine, an antidepressant, showed promising anti-glioblastoma activity, significantly reducing tumor size in preclinical trials.

24 Sep 2024

in vivo News and Research

Dietary zinc may reduce plasmid transfer in gut microbes

Researchers boost natural defenses to fight cataracts and delay the need for surgery

Researchers develop technology to change protein identity in vivo

Scientists unveil a 3D photoacoustic scanner that speeds up vascular imaging for real-time clinical use

Future directions and challenges in harnessing NK cells against Acute Myeloid Leukemia

Novel lipid nanoparticles enhance tissue-specific drug delivery

Traditional Chinese medicine shows potential in cancer treatment

SWIR fluorescence imaging enhances visualization of lymphatic vessels

Discovery of antibodies that boost complement activation against K. pneumoniae

Brusatol may serve as potential adjuvant therapy for pancreatic ductal adenocarcinoma

Perceived stress can directly trigger psoriasis relapse

Innovative CAR-T cells effectively target glioblastoma with reduced toxicity

Multi-omics analysis reveals mechanism of action for ruthenium-based anti-cancer agent

Understanding SARS-CoV-2's viral strategies for infection

Chemical genetics uncovers promising anti-COVID compounds

Optimized nanoadjuvants enhance in situ tumor vaccine for ovarian cancer

Researchers gain new understanding of how immune cells respond to heat during fever

Microbial biomarkers identified in lupus and IBD offer pathways for targeted therapies

New roadmap to advance UK’s bioelectronics for healthcare through materials innovation

Neuroactive drugs show promising anti-glioblastoma effects in preclinical trials

Human iPSCs: A Full Guide to Advanced in Vitro Models and Applications eBook

Lab Matters host Harriet Gould on building a more connected lab community

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

Latest News