Autoimmune Disease News and Research

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Autoimmune Disease is a condition in which the body recognizes its own tissues as foreign and directs an immune response against them.

Uncovering new T cell regulatory processes could help treat autoimmune disease

One of the important cells involved in the immune response is the T follicular helper (Tfh) cell. These are important in the normal process of antibody production following immunization, for instance. However, they are also abnormally increased in number in patients with autoimmune disease, such as systemic lupus erythematosus.

16 Sep 2019

Developing a highly predictive genetic risk score for type 1 diabetes

Paul Tran is working to develop a highly predictive genetic risk score that will tell parents whether their baby is at significant risk for type 1 diabetes.

16 Sep 2019

Study shows how the interplay of two cytokines affects development of Tfh cells

The body's immune response fights against infectious disease, and it safeguards against future infections through vaccination.

15 Sep 2019

FAU physician secures ERC Starting Grant of 1.5 million euros for cutting-edge research

Physician Dr. Andreas Ramming from Friedrich-Alexander-Universität Erlangen-Nürnberg has succeeded in securing research funding in one of the toughest European selection processes.

10 Sep 2019

First potential biomarker identified for postural orthostatic tachycardia syndrome

New research from The University of Toledo College of Medicine and Life Sciences strongly suggests postural orthostatic tachycardia syndrome, or POTS, is an autoimmune disorder and may help pave the way for a simple blood test that could help physicians diagnose the condition.

9 Sep 2019

UAB researchers identify biomarker for early beta cell death in Type 1 diabetes

Beta cells in the pancreas produce insulin. Their death is a key feature of Type 1 diabetes, and that loss starts long before diagnosis. However, there has been no straightforward way to measure that early loss.

8 Sep 2019

Tiny fat bubbles hold key to rebooting the immune system and calming disease process

People living with inflammatory autoimmune disease could benefit from an 'immune system reboot', and researchers have isolated specific cells to target.

7 Sep 2019

New discovery may help identify type 1 diabetes earlier than is currently possible

Type 1 diabetes, an autoimmune disease that typically emerges before the age of 20, wipes out the body's ability to produce insulin--a hormone that's essential to life. Diagnosis often comes after symptoms arise, at which point the disease has taken hold.

30 Aug 2019

Researchers discover unique biological marker for rare autoimmune disease

University of Alberta researchers have identified a unique biological marker that can be used to identify the presence of the rare autoimmune disease myasthenia gravis, predict the course of the disease and identify new, personalized treatments.

29 Aug 2019

AAN publishes new guideline on vaccinations for people with multiple sclerosis

Can a person with multiple sclerosis get regular vaccines? According to a new guideline, the answer is yes. The guideline, developed by the American Academy of Neurology, recommends that people with MS receive recommended vaccinations, including yearly flu shots.

28 Aug 2019

Combination therapy for rheumatoid arthritis may lead to higher remission rates

Researchers at the University of North Carolina Chapel Hill and RTI International, a nonprofit research institute, recently found that patients with early rheumatoid arthritis (RA) may see less disease activity and higher remission rates after biologic therapy plus methotrexate (MTX) rather than either treatment alone.

22 Aug 2019

Genetic risk for autoimmunity may be linked to differences in gut microbiome

Children with increased genetic risk of type 1 diabetes have different gut microbiomes than those with low risk, a new study found.

20 Aug 2019

New circulating immune cell could help predict type 1 diabetes risk

A new Finnish study suggests that type 1 diabetes may in part be caused by a novel subset of immune cells. This is because these cells, called peripheral T helper cells, are found to circulate at a higher rate in children with type 1 diabetes of recent onset, as well as in healthy children who later develop the condition.

20 Aug 2019

Novel T-cell subset may have a role in development of type 1 diabetes

A study conducted at the University of Eastern Finland demonstrated that a recently described T-cell subset, so-called peripheral T helper cells, may have a role in the development of type 1 diabetes.

19 Aug 2019

As states strive to stabilize insurance marketplaces, insurers return

Felicia Morrison is eager to find a health plan for next year that costs less than the one she has and covers more of the medical services she needs for her chronic autoimmune disease.

14 Aug 2019

UC San Diego researchers win $9 million funding to identify cellular cause of type 1 diabetes

University of California San Diego School of Medicine researchers have been awarded nearly $9 million to fund two multi-institutional research projects that use human pluripotent stem cells, CRISPR and human organoids to dissect beta cell defects and create a human cell model of type 1 diabetes aimed at identifying the elusive cellular actions leading to disease onset.

14 Aug 2019

Blood clotting proteins in urine act as potent biomarkers for lupus

The team of researchers at the University of Houston found that blood clotting proteins, both the ones that promote blood clotting (prothrombic) and those that disperse them (thrombolytic) are elevated in the urine of patients with lupus nephritis (LN).

7 Aug 2019

Researchers discover blood clotting proteins in urine as biomarkers of lupus nephritis

University of Houston researcher Chandra Mohan is reporting in Arthritis Research and Therapy that clotting proteins, both those that promote blood clots (pro-thrombotic) and those that work to dissipate them (thrombolytic), are elevated in the urine of patients who suffer from lupus nephritis (LN).

7 Aug 2019

Genetic and environmental factors play major roles in the onset of vitiligo

A pair of new journal articles by researchers at the University of Colorado School of Medicine indicate that both genetic and environmental factors play significant roles in the onset of vitiligo, an autoimmune disease that results in the loss of color in blotches of skin.

31 Jul 2019

An unexpected developmental hierarchy in a rare disease affecting young children

Langerhans cell histiocytosis is a rare disease affecting primarily young children. While LCH may heal by itself without treatment in some patients, others require intensive chemotherapy and suffer from long-term consequences, or may even succumb to the disease.

26 Jul 2019