Nanoparticle News and Research

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In nanotechnology, a particle is defined as a small object that behaves as a whole unit in terms of its transport and properties. It is further classified according to size: in terms of diameter, fine particles cover a range between 100 and 2500 nanometers, while ultrafine particles, on the other hand, are sized between 1 and 100 nanometers.

Mosaic RBD nanoparticles elicit neutralizing antibodies against SARS-CoV-2

The researchers show that the mice immunized with homotypic or mosaic nanoparticles produced broad binding and neutralizing responses, in contrast to plasma antibodies elicited in humans by SARS-CoV-2 infection. The RBD nanoparticles induced cross-reactive IgG responses in the immunized mice.

19 Nov 2020

CRISPR/Cas9 system is highly effective in treating metastatic cancers

Researchers at Tel Aviv University (TAU) have demonstrated that the CRISPR/Cas9 system is very effective in treating metastatic cancers, a significant step on the way to finding a cure for cancer.

19 Nov 2020

Government-funded scientists laid the groundwork for billion-dollar vaccines

When he started researching a troublesome childhood infection nearly four decades ago, virologist Dr. Barney Graham, then at Vanderbilt University, had no inkling his federally funded work might be key to deliverance from a global pandemic.

18 Nov 2020

A new optical imaging technology for nanoscale objects

Current state-of-the-art techniques have clear limitations when it comes to imaging the smallest nanoparticles, making it difficult for researchers to study viruses and other structures at the molecular level.

17 Nov 2020

Synthetic protein nanoparticle may treat aggressive brain cancer

A new synthetic protein nanoparticle capable of slipping past the nearly impermeable blood-brain barrier in mice could deliver cancer-killing drugs directly to malignant brain tumors, new research from the University of Michigan shows.

11 Nov 2020

Universal nanoparticle platform may help in rapid development of a COVID-19 vaccine

A research group in China recently published a paper on the pre-print server bioRxiv* that reports the performance of a potentially universal nanoparticle platform that may prove useful for the rapid development of a COVID-19 vaccine, as well as other vaccines in the future.

8 Nov 2020

Princeton professor selected to receive new award recognizing faculty innovation

Robert Prud'homme, professor of chemical and biological engineering at Princeton University, has been selected to receive the inaugural Dean for Research Award for Distinguished Innovation for the invention of flash nanoprecipitation, a method for creating nanoparticles that promises to improve the delivery of drugs throughout the body.

30 Oct 2020

New method could help increase effectiveness of vaccines against coronavirus

A University at Buffalo-led research team has discovered a technique that could help increase the effectiveness of vaccines against the novel coronavirus, the virus that causes COVID-19.

29 Oct 2020

DNase coated melanin-like nanospheres for sepsis treatment in severe COVID

As the treatment of severe COVID-19 is very difficult, the researchers from the Korea Research Institute of Biosciences and Biotechnology (KRIBB) suggested that DNase-1 can be utilized to dissolve the neutrophil extracellular traps (NETs), hence halting the further progression of COVID-19.

27 Oct 2020

Biomimetic virus-like particles for safer positive controls in SARS-CoV-2 detection

In an attempt to overcome these issues, a team of researchers from various departments at the University of California San Diego recently proposed using biomimetic virus-like particles (VLPs) as positive controls for assays used in SARS-CoV-2 detection. Their study is published on the preprint server bioRxiv.

23 Oct 2020

Protein delivery to the testes restores male fertility in mice

According to the Mayo Clinic, about 15% of couples are infertile, and male infertility plays a role in over one-third of these cases.

21 Oct 2020

Wyatt technology announces breakthrough in Field Flow Fractionation (FFF) separation technology

Wyatt Technology, the world leader in instrumentation for absolute macromolecular and nanoparticle characterization, reveals the launch of its 6th-generation Eclipse FFF system that represents an entirely new paradigm of FFF technology.

From Waters | Wyatt Technology 21 Oct 2020

Scientists discover mechanism linking gum disease to inflammatory conditions

The link between periodontal (gum) disease and other inflammatory conditions such as heart disease and diabetes has long been established, but the mechanism behind that association has, until now, remained a mystery.

20 Oct 2020

Sanofi Translate Bio MRT5500 COVID-19 vaccine shows promise in preclinical trials

The COVID-19 pandemic is threatening to come back in greater intensity during the winter and fall. Faced with this threat, vaccine development efforts are entering a phase of renewed focus, attempting to identify antigens capable of eliciting protective levels of neutralizing antibodies. A new study published on the preprint server bioRxiv* in October 2020 reports on a novel mRNA vaccine candidate's performance in two animal models.

16 Oct 2020

The COVID-19 vaccine pipeline

Researchers from Mayo Clinic, United States of America, have reviewed the immunity developed against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that causes COVID-19 disease.

14 Oct 2020

New drug delivery systems can improve treatment for diseases that affect connective tissues

University of Delaware Professor Kristi Kiick is leading collaborative research to create new drug delivery systems with the potential to improve treatment for diseases that affect connective tissues, such as osteoarthritis or rheumatoid arthritis, which is an autoimmune disease.

9 Oct 2020