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Study finds evidence for repurposing thiostrepton as an anti-rhabdomyosarcoma drug

Rhabdomyosarcoma (RMS) accounts for up to 10% of childhood cancers and nearly half of pediatric soft tissue sarcomas.

27 Oct 2025

Mitochondria and lysosomes work together to control regulatory T cell activation

Metabolism guides the activation states of regulatory T cells, the immune cells that prevent inappropriate activation of the immune system.

24 Oct 2025

New insight into TRPM3 heat sensor reveals how the body detects temperature

The ability to sense heat protects the body from burns and injury. But how the body actually feels temperature has remained an elusive mystery.

24 Oct 2025

First multiple sclerosis patient in the UK receives CAR T cell therapy in groundbreaking trial

A multiple sclerosis (MS) patient in the UK was the first to receive CAR T cell therapy, invented by UCL researchers, in a clinical trial testing whether this personalized treatment can slow or even halt the progression of the disease.

24 Oct 2025

Unveiling the dual role of HIV integrase in viral replication

The rate of HIV infection continues to climb globally. Around 40 million people live with HIV-1, the most common HIV strain.

24 Oct 2025

Revolutionizing blood diagnostics with real-time QPM technology

Blood tests are among the most common tools in medicine. Scientists are working to make blood cell imaging faster and more intuitive so that doctors can make fast and accurate diagnostic decisions.

24 Oct 2025

Researchers map the complex sugar chains attached to rat serum proteins

A comprehensive study mapped the dynamic glycosylation landscape of rat serum proteins, uncovering sex- and time-dependent variations with clear cell-type specificity.

24 Oct 2025

Leveraging the power of T cells for more effective and durable cancer immunotherapies

T cells play central roles in the adaptive immune response against cancer. Their functional inactivation is a primary driver of tumor progression, making the reactivation of T cell function a main goal in immunotherapy.

24 Oct 2025

Advancements in organoids could transform treatment of spinal cord injury and peripheral nerve injury

A recent review published in Engineering explores the construction and potential applications of spinal cord and peripheral nerve organoids for regenerative medicine in neurotrauma.

24 Oct 2025

Discovering the role of lingual and buccal cells in tooth development

A novel study on the natural coordination of tooth development in time and space, led by Dr. Han-Sung Jung at the Yonsei University College of Dentistry, Korea, has discovered that "lingual" cells on the side of the tongue form the tooth, whereas those toward the cheek, called "buccal cells," form the bones and gums, guided by signaling molecules like WNT and BMP.

24 Oct 2025

Bio-Rad’s iQ-Check Enterobacteriaceae Kit validated for detection of Enterobacteriaceae in infant formula and cereals

Bio-Rad Laboratories, Inc., a global leader in life science research and clinical diagnostics products, today announced that MicroVal, the international certification organization for the validation and approval of alternative methods for the microbiological analysis of food and beverages, has approved iQ-Check™ Enterobacteriaceae Kit for the real-time PCR detection of Enterobacteriaceae (EB) in infant formula, infant cereal with and without probiotics, and related ingredients.

From Bio-Rad Laboratories 24 Oct 2025

Researchers uncover and inhibit a key cell death pathway in severe cutaneous adverse reactions

A collaborative research group led by Haruna Kimura (graduate student), Dr. Akito Hasegawa (Assistant Professor), and Prof. Riichiro Abe from the Division of Dermatology, Niigata University Graduate School of Medical and Dental Sciences, together with Prof. Takemasa Ozawa from the Department of Chemistry, School of Science, The University of Tokyo, and Dr. Yoichi Ogawa (Lecturer) from the Department of Dermatology, Faculty of Medicine, University of Yamanashi, has developed a novel therapeutic candidate that may improve the prognosis of severe cutaneous adverse reactions such as Stevens–Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN).

24 Oct 2025

Toxic compounds from heated e-cigarette fluids can damage lung cells

A study by University of California, Riverside, scientists has found that two toxic chemicals can form when the main ingredient in most e-cigarette fluids is heated, and that these compounds can harm human lung cells.

23 Oct 2025

How COVID mRNA vaccines may make cancer treatments more effective

Researchers found that COVID-19 mRNA vaccines, when given within 100 days of starting immune checkpoint inhibitors, were linked to significantly longer survival in lung and melanoma cancer patients. The vaccines trigger a powerful type-I interferon response that primes tumors to become more responsive to immunotherapy.

23 Oct 2025

New discovery reshapes understanding of how brain inflammation arises in Alzheimer's disease

Researchers at the University of California, Irvine, have uncovered an unexpected molecular partnership that reshapes scientists' understanding of how brain inflammation arises in Alzheimer's disease.

23 Oct 2025

Les Turner Symposium on ALS brings researchers and clinicians to discuss new research findings

The 15th annual Les Turner Symposium on ALS will be held on Monday, Nov. 3, 2025 in Chicago. Hosted by the Les Turner ALS Foundation and the Les Turner ALS Center at Northwestern Medicine, this event will gather leading ALS researchers and clinicians to discuss the latest research and perspectives on the disease.

23 Oct 2025

International experts publish guidelines on the administration of gene therapy for hereditary hearing loss

Up to 60% of congenital and early-onset hearing loss is caused by genetic mutations in an inherited gene, and gene therapy has recently emerged as a potential treatment option.

23 Oct 2025

Antibody discovery could provide new treatment options for aggressive breast cancers

A new potential antibody therapy strategy which restricts the growth of treatment-resistant breast cancers has been developed by scientists.

23 Oct 2025

New York Regional Diabetes Research Center established with $10.8 million NIH grant

Albert Einstein College of Medicine has received a five-year, $10.8 million grant from the National Institutes of Health (NIH) to create the New York Regional Diabetes Research Center (NYR-DRC), a newly expanded multi-institutional center co-led with the Icahn School of Medicine at Mount Sinai and Weill Cornell Medicine.

23 Oct 2025

Discovery could pave the way for new generation of RNA-based cancer treatments

Researchers fhave created a new type of drug molecule that can precisely destroy TERRA, an RNA molecule that helps certain cancer cells survive.

23 Oct 2025

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B Cell News and Research

Study finds evidence for repurposing thiostrepton as an anti-rhabdomyosarcoma drug

Mitochondria and lysosomes work together to control regulatory T cell activation

New insight into TRPM3 heat sensor reveals how the body detects temperature

First multiple sclerosis patient in the UK receives CAR T cell therapy in groundbreaking trial

Unveiling the dual role of HIV integrase in viral replication

Revolutionizing blood diagnostics with real-time QPM technology

Researchers map the complex sugar chains attached to rat serum proteins

Leveraging the power of T cells for more effective and durable cancer immunotherapies

Advancements in organoids could transform treatment of spinal cord injury and peripheral nerve injury

Discovering the role of lingual and buccal cells in tooth development

Bio-Rad’s iQ-Check Enterobacteriaceae Kit validated for detection of Enterobacteriaceae in infant formula and cereals

Researchers uncover and inhibit a key cell death pathway in severe cutaneous adverse reactions

Toxic compounds from heated e-cigarette fluids can damage lung cells

How COVID mRNA vaccines may make cancer treatments more effective

New discovery reshapes understanding of how brain inflammation arises in Alzheimer's disease

Les Turner Symposium on ALS brings researchers and clinicians to discuss new research findings

International experts publish guidelines on the administration of gene therapy for hereditary hearing loss

Antibody discovery could provide new treatment options for aggressive breast cancers

New York Regional Diabetes Research Center established with $10.8 million NIH grant

Discovery could pave the way for new generation of RNA-based cancer treatments

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

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How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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