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Dipeptides reveal clues to the origin of life’s instructions

Genes are the building blocks of life, and the genetic code provides the instructions for the complex processes that make organisms function.

17 Sep 2025

A new tool in the fight against obesity: Orforglipron's substantial weight loss results

New research presented at the Annual Meeting of the European Association for the Study of Diabetes in Vienna, Austria (Sept 15-19) and simultaneously published in NEJM shows that daily treatment with the new once-daily GLP-1 agonist orforglipron results in substantial weight loss in people living with obesity that do not have type 2 diabetes.

17 Sep 2025

Exercise found to reduce artery hardening after weight loss in adults with obesity

Maintaining weight loss with regular exercise rather than the glucagon-like peptide-1 receptor agonist (GLP-1RA) liraglutide, a drug used to treat type 2 diabetes and obesity, seems to reduce atherosclerosis development in adults with obesity-a leading underlying cause of cardiovascular disease.

17 Sep 2025

Sapio Sciences introduces world’s first 3rd-generation ELN

Sapio Sciences, the science-aware™ AI lab informatics platform, today announced the launch of the world’s first 3rd-generation Electronic Lab Notebook (ELN) that thinks like a scientist, Sapio ELaiN.

From Sapio Sciences 17 Sep 2025

CoQ10 shows promise in boosting female fertility by reviving aging eggs

Researchers reviewed evidence on Coenzyme Q10 (CoQ10) and found it may enhance mitochondrial function, improve oocyte quality, and counteract age-related fertility decline. The review highlights promising results from clinical, preclinical, and in vitro studies but calls for larger trials to confirm safety, dosing, and effectiveness.

16 Sep 2025

Neurons play a key role in reducing lung inflammation in pulmonary fibrosis

Researchers at the University of Calgary studying a lethal lung disease called pulmonary fibrosis have found neurons, which were known to help detect pain, are also critical for reducing harmful lung inflammation that leads to the disease.

16 Sep 2025

Researchers provide new insights into how exercise helps lose weight

Researchers at Baylor College of Medicine, Jan and Dan Duncan Neurological Research Institute (Duncan NRI) at Texas Children's Hospital, Stanford University School of Medicine and collaborating institutions provide new insights into how exercise helps lose weight.

16 Sep 2025

Study uncovers the tradeoff between fast immune defense and long-term inflammation

Some of our biggest threats can come in the tiniest forms-viruses and bacteria. Thankfully, we are born with a built-in defense system, our innate immune system that protects us in our youth but can turn against us as we age.

16 Sep 2025

Novel RNA target offers hope for improving outcomes in patients with chronic limb ischemia

Mark W. Feinberg, MD, cardiologist with the Mass General Brigham Heart and Vascular Institute and professor of medicine at Harvard Medical School, is the senior author of a paper published in the Journal of Clinical Investigation, "A smooth muscle cell lncRNA controls angiogenesis in chronic limb-threatening ischemia through miR-143-3p/HHIP signaling."

13 Sep 2025

Texas Tech research team earns $3 million renewal to advance stroke therapy

Stroke research aims to understand the brain's self-protective and repair mechanisms. Gaining detailed insight into these mechanisms is crucial as such knowledge could lead to newly developed medications and interventions which mimic or engage the brain's self-protective/repair mechanisms, leading to innovative stroke therapies.

13 Sep 2025

Abnormal protein activity found to promote cell migration and spread of glioblastoma

Ever wondered how the different cells in our body communicate with each other to fulfill their different roles-be it cells repairing a tissue injury or immune cells moving towards an invading pathogen (microorganisms that causes disease) to engulf it?

11 Sep 2025

Scientists uncover brain circuit that turns cravings into eating behavior

Researchers found that the bed nucleus of the stria terminalis integrates pleasure signals from central amygdala prodynorphin neurons and hunger signals from agouti-related peptide neurons to drive consumption. Manipulating this bed nucleus of the stria terminalis circuit bidirectionally altered food intake and body weight in mice.

11 Sep 2025

Rare ABCA7 gene variants linked to Alzheimer’s risk

A new study from MIT neuroscientists reveals how rare variants of a gene called ABCA7 may contribute to the development of Alzheimer's in some of the people who carry it.

10 Sep 2025

Bottlebrush particles deliver large range of chemotherapy drugs directly to tumor cells

Using tiny particles shaped like bottlebrushes, MIT chemists have found a way to deliver a large range of chemotherapy drugs directly to tumor cells.

10 Sep 2025

Johns Hopkins team develops urine-based test for prostate cancer detection

Researchers at the Johns Hopkins Kimmel Cancer Center, Johns Hopkins All Children's Hospital and four other institutions have devised a novel method to test for prostate cancer using biomarkers present in urine, funded in part by the National Institutes of Health.

9 Sep 2025

Ketogenic diet shows promise in reducing depression symptoms in college students

A new study shows an association between at least 10 weeks of following a well-formulated ketogenic diet and a roughly 70% decrease in depression symptoms among a small group of college students.

9 Sep 2025

Experts review the evidence on coenzyme Q10 and cognitive decline

Researchers reviewed evidence on coenzyme Q10 (CoQ10) and cognition, finding strong biological support and positive results in animal models but mixed outcomes in human trials. Larger, high-quality studies are needed to clarify whether CoQ10 can protect against cognitive decline and neurodegenerative diseases.

9 Sep 2025

'Resistin like molecule gamma' punches holes into heart cells after myocardial infarction

Nina Kumowski, MD, of the Department of Radiology and Center for Systems Biology at Massachusetts General Hospital, is the lead author and Matthias Nahrendorf, MD, PhD of the Department of Radiology and Center for Systems Biology at MGH, is the senior author of a paper published in Science, "Resistin-like molecule γ attacks cardiomyocyte membranes and promotes ventricular tachycardia."

9 Sep 2025

Unlocking the secrets of oral bacteria to fight tooth decay

If Wenjun Zhang has her way, no one will ever have to brush or floss again.

5 Sep 2025

Mucus-inspired hydrogel improves healing in animal models of gastric injury

Hydrogels-materials like gelatin that can absorb and hold water-can aid wound healing and enable slow-release drug delivery, but they usually break down in acidic environments like the stomach.

4 Sep 2025

Molecule News and Research

Dipeptides reveal clues to the origin of life’s instructions

A new tool in the fight against obesity: Orforglipron's substantial weight loss results

Exercise found to reduce artery hardening after weight loss in adults with obesity

Sapio Sciences introduces world’s first 3rd-generation ELN

CoQ10 shows promise in boosting female fertility by reviving aging eggs

Neurons play a key role in reducing lung inflammation in pulmonary fibrosis

Researchers provide new insights into how exercise helps lose weight

Study uncovers the tradeoff between fast immune defense and long-term inflammation

Novel RNA target offers hope for improving outcomes in patients with chronic limb ischemia

Texas Tech research team earns $3 million renewal to advance stroke therapy

Abnormal protein activity found to promote cell migration and spread of glioblastoma

Scientists uncover brain circuit that turns cravings into eating behavior

Rare ABCA7 gene variants linked to Alzheimer’s risk

Bottlebrush particles deliver large range of chemotherapy drugs directly to tumor cells

Johns Hopkins team develops urine-based test for prostate cancer detection

Ketogenic diet shows promise in reducing depression symptoms in college students

Experts review the evidence on coenzyme Q10 and cognitive decline

'Resistin like molecule gamma' punches holes into heart cells after myocardial infarction

Unlocking the secrets of oral bacteria to fight tooth decay

Mucus-inspired hydrogel improves healing in animal models of gastric injury

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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