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How antibody-drug conjugates are redefining targeted cancer therapy

Antibody-drug conjugates are rapidly expanding cancer therapies, with 19 approved globally and many more in development, but their success depends on better targets, payloads, linkers, dosing, and patient selection. The Cell review shows that next-generation ADCs could widen treatment options, but safety, resistance, tumor heterogeneity, and clinical translation remain major barriers.

19 May 2026

Stem cell infusions improve symptoms in butterfly skin disease

The intravenous infusion of mesenchymal stem cells from family donors is safe and improves symptoms such as pruritus (itching), sleep disturbances, and fatigue associated with Recessive Dystrophic Epidermolysis Bullosa (RDEB), popularly known as "butterfly skin".

18 May 2026

UCLA researchers identify potential drug target for treating Fragile X syndrome

UCLA Health researchers have identified a potential drug target for treating Fragile X syndrome, the most common genetic cause of intellectual disability and autism that affects roughly 1 in 2,000 boys.

18 May 2026

Azithromycin fails to improve severe wheezing in preschool children

A study led by researchers at the University of Arizona College of Medicine – Tucson showed that giving the antibiotic azithromycin did not help preschool children seen in the hospital emergency room with bouts of severe wheezing.

18 May 2026

DNA-guided CRISPR system targets RNA and expands Cas12 beyond gene editing

Researchers developed ΨDNA, a DNA-based CRISPR guide that allows Cas12 enzymes to target RNA with high specificity while retaining compatibility with DNA-editing workflows. The platform detected HCV RNA in clinical samples and enabled programmable RNA knockdown, multiplex targeting, and RNA modification in human cells.

18 May 2026

New therapies could help type 1 diabetes care move beyond insulin alone

Disease-modifying therapies for type 1 diabetes are beginning to move care beyond insulin replacement by targeting immune dysregulation, beta-cell stress, and preservation of endogenous beta-cell function. Teplizumab marks a major clinical milestone, but the review emphasizes that durable metabolic remission will likely require earlier screening, better patient selection, and sequential or combination therapies.

18 May 2026

Low-frequency ultrasound waves directly manipulate blood flow properties

For decades, ultrasound has been associated with diagnostics – a routine scan in a hospital room, a monitor displaying organs, tissues, or the first image of a baby.

18 May 2026

Tezepelumab reduces asthma exacerbations in diverse patient population

The drug tezepelumab was shown to significantly reduce exacerbations in people with severe asthma in clinical trials.

18 May 2026

Global consortium renames polycystic ovary syndrome to reflect science

First, it was named after two men. Then, it was named for a false premise. Now, after more than a century, one of the most common hormone disorders affecting women worldwide has a name that reflects the science.

18 May 2026

Once-nightly oral pill helps control obstructive sleep apnea

A once-nightly oral pill helped control obstructive sleep apnea in a large, phase 3 clinical trial presented at the 2026 ATS International Conference.

18 May 2026

Gut microbiome metabolite butyrate relieves chronic jaw joint pain

Temporomandibular joint (TMJ) pain is associated with disrupted gut microbiome metabolites. Researchers reveal that butyrate, administered as tributyrin, alleviates pain by restoring histone acetylation and reversing gene regulatory changes in the brain.

18 May 2026

Blood test detects tumor DNA to guide advanced cancer treatment

A blood test that detects tumor DNA circulating in the bloodstream may help select the most effective treatment options for cancer patients whose tumors have started to spread, according to one of the largest randomized controlled trials of its kind presented at the Congress of the European Society for Radiotherapy and Oncology (ESTRO 2026).

18 May 2026

Olive waste extract may help lower fat and improve muscle markers

A polyphenol-rich olive oil byproduct may enhance muscle health, reducing fat mass and improving antioxidant markers in adults with metabolic risk factors.

18 May 2026

Research offers clearer genetic blueprint of breast cancer variants

A study led by Dr Jason Pitt, Principal Investigator at the Cancer Science Institute of Singapore (CSI Singapore), has identified eight new "signatures" of DNA patterns (gains and/or losses) in breast cancer.

18 May 2026

Aged immune cells may drive memory decline by releasing a brain-aging protein

A preclinical mouse study in Immunity suggests that aged circulating CD8+ T cells can disrupt hippocampal function and impair learning and memory. The findings point to granzyme K, a secreted factor linked to age-associated CD8+ T cells, as a potential target for restoring aspects of cognition in aging.

17 May 2026

Targeted radiotherapy may delay progression in metastatic breast cancer patients

Treating breast cancer that has begun to spread around the body with targeted radiotherapy could help patients to live longer without their cancer getting worse, according to the results of a small randomised controlled trial presented at the Congress of the European Society for Radiotherapy and Oncology (ESTRO 2026).

17 May 2026

Multi-institutional trial explores new lifeline for advanced prostate patients

For men with advanced prostate cancer that no longer responds to standard hormone therapies, treatment options are limited – and time matters. As the disease progresses, the window for effective, less intensive treatments begins to close.

15 May 2026

Evidence shows RF-TC improves seizure control by altering brain networks

Drug-resistant epilepsy affects millions of people worldwide and remains one of the most difficult neurological disorders to treat. For patients whose seizures continue despite medication, surgical removal of seizure-causing tissue can be effective.

15 May 2026

Endoscopic sleeve gastroplasty outperforms oral semaglutide in short-term weight loss

A comparative study, presented at ESGE Days 2026, has found that endoscopic sleeve gastroplasty (ESG) is associated with significantly greater short-term weight loss than oral semaglutide in adults with obesity.

15 May 2026

Addressing depression and anxiety in primary care improves chronic pain management

A study published this month in the American Journal of Managed Care explores how integrating behavioral health care into primary care can improve outcomes and be cost-effective for adults with depression, anxiety and chronic pain who are on long-term opioid therapy.

15 May 2026