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New computer algorithm offers a path toward pan-influenza and coronavirus vaccine

A novel computer algorithm that could create a broadly reactive influenza vaccine for swine flu also offers a path toward a pan-influenza vaccine and possibly a pan-coronavirus vaccine as well, according to a new paper published in Nature Communications.

2 Mar 2021

New nanoparticle-delivered COVID-19 vaccine candidate shows efficacy in ferret model

Researchers from Cleveland Clinic's Global Center for Pathogen Research & Human Health have developed a promising new COVID-19 vaccine candidate that utilizes nanotechnology and has shown strong efficacy in preclinical disease models.

2 Mar 2021

Novel dual-targeting drug could become a next-generation treatment for EBV-related cancers

A Hong Kong Baptist University-led research team has developed a novel drug which has the potential to become a next-generation treatment for cancers associated with Epstein-Barr virus (EBV).

2 Mar 2021

Evonik partners with BioNTech to manufacture lipids for COVID-19 vaccine

Caused by SARS-CoV-2, the coronavirus disease 2019 (COVID-19) pandemic continues to spread across the globe.

From Evonik 2 Mar 2021

Successful SARS-CoV-2 vaccination hinges on non-pharmaceutical interventions and vaccine deployment strategies

A thought-provoking new study server discusses the factors that determine the successful use of available vaccines to mitigate incidence and mortality rates for COVID-19.

2 Mar 2021

Moderna vaccine reduces viral spread by at least 60 percent, finds study

An interesting new study by researchers at Harvard T.H. Chan School of Public Health in the U.S. suggests that the currently used Moderna vaccine reduces viral shedding by about 60%.

2 Mar 2021

Studies reveal the promise of newly engineered bispecific antibodies against tumor cells

Three studies - one each in Science, Science Translational Medicine, and Science Immunology - reveal the promise of newly engineered bispecific antibodies, including by demonstrating their power against previously inaccessible tumor cell targets for the first time, in two cases.

2 Mar 2021

New injectable hydrogel could heal cardiac tissue after heart attack

Researchers at CÚRAM, the SFI Research Centre for Medical Devices based at National University of Ireland Galway, and BIOFORGE Lab, at the University of Valladolid in Spain, have developed an injectable hydrogel that could help repair and prevent further damage to the heart muscle after a heart attack.

2 Mar 2021

Study analyzes factors that make people susceptible to false information about health

A new study from University of Kansas journalism & mass communication researchers examines what influences people to be susceptible to false information about health and argues big tech companies have a responsibility to help prevent the spread of misleading and dangerous information.

2 Mar 2021

Unique nanoparticles can package and deliver gene-editing machinery to the liver

The genome editing technology CRISPR has emerged as a powerful new tool that can change the way we treat disease. The challenge when altering the genetics of our cells, however, is how to do it safely, effectively, and specifically targeted to the gene, tissue and organ that needs treatment.

2 Mar 2021

Study reveals presence of glial plasticity, offers future therapeutic strategy for epilepsy

Tohoku University scientists and their colleagues in Germany have revealed that a first-time exposure to only a brief period of brain hyperactivity resulted in an acute breakdown of the inter-cellular network of glial cells.

2 Mar 2021

Scientists establish infection models for SARS-CoV-2 UK & South African variants

New research suggests Syrian golden hamsters could be a potentially useful preclinical model for testing vaccine immunity against the acute respiratory syndrome coronavirus 2 (SARS-CoV-2) B.1.17 and B.1.351 variant.

1 Mar 2021

High level of COVID-19 vaccine hesitancy found among Black Americans

Black Americans have a high level of vaccine hesitancy and mistrust of COVID-19 vaccines, including among Black health care workers, according to a new RAND Corporation survey.

1 Mar 2021

NYU Oral Cancer Center receives $3.1 million grant to explore the interplay between nerves and cancer

NYU Oral Cancer Center has been awarded a five-year, $3.1 million grant (R01 CA231396) by the National Cancer Institute (NCI), part of the National Institutes of Health (NIH).

1 Mar 2021

Comparative analysis of SARS-CoV-2 antivirals leads to new potential treatment for COVID-19

Scientists compared the in vitro efficacy and cytotoxicity profiles of PF-00835231 and remdesivir in two human model systems for SARS-CoV-2 infection.

1 Mar 2021

Researchers evaluate surrogate large-scale SARS-CoV-2 serosurveillance test

A team of international scientists has recently evaluated a surrogate virus neutralization test for severe acute respiratory coronavirus 2 (SARS-CoV-2) and observed that it is highly efficacious for detecting anti-SARS-CoV-2 neutralizing antibodies in serum samples. According to the scientists, the test can be effectively used for population-level serosurveillance and evaluation of vaccine efficacy. The study is currently available on the medRxiv* preprint server.

1 Mar 2021

Single-dose of BNT162b2 vaccine may not be protective without prior SARS-CoV-2 infection

A new study by researchers at Imperial College London, UK, discusses the effect of a vaccine dose, specifically the BNT162b2 candidate (also known as the ‘Pfizer-BioNTech’ vaccine), on neutralizing antibody titers in individuals who have already been infected with the virus.

1 Mar 2021

One in seven people in England show SARS-CoV-2 antibodies, finds study

The REal-time Assessment of Community Transmission-2 (REACT-2) program completed its fifth round of community surveys in the days between January 26 and February 8, 2021. The findings appear in a new article in the BMJ on February 25, 2021, showing that natural infection and vaccination together account for around 14% seropositivity rates in England at present.

1 Mar 2021

Could SARS-CoV-2 antibody tests before first vaccine dose help increase coverage and protection?

A new study by scientists in the UK raises the very useful hypothesis that natural infection may help spread the vaccine thinner without loss of efficacy.

1 Mar 2021

Pfizer-BioNTech SARS-CoV-2 vaccine effective for wide range of Covid-19–related outcomes

The Pfizer-BioNTech mRNA vaccine was shown to be 95% effective in preventing severe COVID-19 infection in clinical trials. However, given that the acute respiratory syndrome coronavirus 2 (SARS-CoV-2) continues to spread and evolve into several concerning variants, it remained unknown how the vaccine would respond in a real-life setting.

1 Mar 2021

Efficacy News and Research

New computer algorithm offers a path toward pan-influenza and coronavirus vaccine

New nanoparticle-delivered COVID-19 vaccine candidate shows efficacy in ferret model

Novel dual-targeting drug could become a next-generation treatment for EBV-related cancers

Evonik partners with BioNTech to manufacture lipids for COVID-19 vaccine

Successful SARS-CoV-2 vaccination hinges on non-pharmaceutical interventions and vaccine deployment strategies

Moderna vaccine reduces viral spread by at least 60 percent, finds study

Studies reveal the promise of newly engineered bispecific antibodies against tumor cells

New injectable hydrogel could heal cardiac tissue after heart attack

Study analyzes factors that make people susceptible to false information about health

Unique nanoparticles can package and deliver gene-editing machinery to the liver

Study reveals presence of glial plasticity, offers future therapeutic strategy for epilepsy

Scientists establish infection models for SARS-CoV-2 UK & South African variants

High level of COVID-19 vaccine hesitancy found among Black Americans

NYU Oral Cancer Center receives $3.1 million grant to explore the interplay between nerves and cancer

Comparative analysis of SARS-CoV-2 antivirals leads to new potential treatment for COVID-19

Researchers evaluate surrogate large-scale SARS-CoV-2 serosurveillance test

Single-dose of BNT162b2 vaccine may not be protective without prior SARS-CoV-2 infection

One in seven people in England show SARS-CoV-2 antibodies, finds study

Could SARS-CoV-2 antibody tests before first vaccine dose help increase coverage and protection?

Pfizer-BioNTech SARS-CoV-2 vaccine effective for wide range of Covid-19–related outcomes

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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