Insulin News and Research

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Insulin is a hormone that is needed to convert glucose, starches and other food into energy needed for daily life. Insulin allows cells to use glucose for fuel and is secreted by beta cells in the islets of Langerhans. The release of insulin from the pancreas is stimulated by increased blood glucose, vagal nerve stimulation, and other factors. Insulin is obtained from various animals and available in a variety of preparations. Commercial insulin preparations differ in a number of ways, including differences in the animal species from which they are obtained; their purity, concentration, and solubility; and the time of onset and duration of their biologic action. An oral hypoglycemic agent is not a form of insulin therapy.

Hyaluronidase-1 emerges as a key regulator of postmeal blood sugar

A recent study published in Life Metabolism has uncovered a surprising new player in the body's ability to regulate blood sugar after eating.

15 May 2025

Lipid accumulation levels reveal hidden osteoporosis risk

Researchers investigate the use of lipid accumulation products as a predictor of osteoporosis.

14 May 2025

New approach directly combats the progression of Alzheimer’s and ALS

Scientists at Northwestern University have developed a new approach that directly combats the progression of neurodegenerative diseases like Alzheimer's disease and amyotrophic lateral sclerosis (ALS).

14 May 2025

Adult-onset type 1 diabetes linked to higher cardiovascular and mortality risk

A new study in the European Heart Journal shows that people who develop type 1 diabetes in adulthood have an increased risk of cardiovascular disease and death, and that those diagnosed later in life do not have a better prognosis than those diagnosed earlier.

14 May 2025

Lipid buildup predicts weaker bones once it passes a critical threshold

A large cross-sectional study using NHANES data found a non-linear negative relationship between lipid accumulation product (LAP) and lumbar spine bone mineral density (BMD). The association became significant only above a threshold value (ln-LAP > 2.846), independent of BMI.

12 May 2025

Novel Alzheimer's therapy shows low risk of severe side effects

The Food and Drug Administration's approval in 2023 of lecanemab - a novel Alzheimer's therapy shown in clinical trials to modestly slow disease progression - was met with enthusiasm by many in the field as it represented the first medication of its kind able to influence the disease.

12 May 2025

City of Hope opens largest outpatient facility to enhance cancer care

As advances in early detection and treatment transform cancer into a chronic disease, City of Hope, one of the largest and most advanced cancer research and treatment organizations in the U.S. with its National Medical Center named top 5 in the nation for cancer by U.S. News & World Report, opens its largest outpatient facility among its network of 38 U.S. locations.

12 May 2025

Adverse waist-to-height ratio trajectories during childhood linked to early cardiometabolic risk

New research being presented at this year's European Congress on Obesity (ECO) in Malaga, Spain (11-14 May) reveals that adverse waist-to-height ratio trajectories (a marker for central obesity) during childhood may increase cardiometabolic and cardiovascular risk at 10 years old.

11 May 2025

GLP-1 receptor agonists improve mood and metabolic health in adults with mental illness

Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) can lead to significant weight loss and improve blood sugar control in adults with severe mental illness, as well as having positive effects on mood, well-being, and quality of life in those both with and without mental illness, according to a systematic review of the available evidence being presented at this year's European Congress on Obesity (ECO) in Malaga, Spain (11-14 May).

11 May 2025

Delayed puberty in boys raises risk of type 2 diabetes later in life, study shows

A large Israeli study found that boys who experience delayed puberty are significantly more likely to develop type 2 diabetes in early adulthood. This increased risk persists even after accounting for body weight, socio-economic status, and other confounding factors.

10 May 2025

Mitochondrial transplantation as a strategy to address metabolic decline in aging

Announcing a new publication for Acta Materia Medica journal. Aging impairs adipose tissue function and contributes to metabolic disorders, such as obesity and insulin resistance.

10 May 2025

Study reveals colonic inflammation as the trigger for beta cell growth in obesity

Researchers at the Tohoku University Graduate School of Medicine have uncovered a key primary step in the hepatic ERK pathway that leads to increased insulin production.

9 May 2025

Trump team faces key legal decision that could put mental health parity in peril

The Trump administration must soon make a decision that will affect millions of Americans' ability to access and afford mental health and addiction care.

9 May 2025

New stem cell model mimics alpha cell behavior in diabetic conditions

Mor than 800 million people worldwide are living with diabetes, according to World Health Organization (WHO) estimates, with numbers steadily increasing.

8 May 2025

Study reveals potential new strategy to prevent or slow progression of Type 1 diabetes

A study co-led by Indiana University School of Medicine researchers presents a potential new strategy to prevent or slow the progression of Type 1 diabetes by targeting an inflammation-related protein known to drive the disease.

7 May 2025

How urine caffeine levels may help detect diabetic eye damage early

Researchers found that higher urinary levels of caffeine and specific metabolites, especially in men, were significantly associated with diabetic retinopathy risk. The cross-sectional study used NHANES 2009–2014 data and highlights potential biomarkers for early detection in diabetic populations.

7 May 2025

Canadian study links ultra processed foods to poor health outcomes

A landmark study exploring Canadians' consumption of chips, frozen pizzas, breakfast cereals and other ultra-processed foods typically loaded with fat, sugar and additives has confirmed these foods are directly and significantly linked to poor health outcomes.

7 May 2025

Diabetes drug shows promise for treating prostate cancer

An international team of scientists led by the Medical University of Vienna has identified similarities in the mechanisms of diabetes and cancer: as the researchers show, the protein PPARγ, which is central to the regulation of metabolic processes, can also influence the growth of prostate cancer cells.

6 May 2025

Where and why men die younger: global data breaks it down

A global study published in PLOS Medicine examined sex-disaggregated data on hypertension, diabetes, and HIV/AIDS across 204 countries. It revealed significant but context-dependent differences in disease burden, care access, and outcomes between males and females.

4 May 2025

Semaglutide clears liver inflammation and cuts fibrosis in MASH patients, trial shows

A phase 3 trial shows that once-weekly semaglutide significantly improves liver histology in patients with metabolic dysfunction-associated steatohepatitis (MASH). The interim results also reveal meaningful weight loss and improved cardiometabolic markers, with a favorable safety profile.

4 May 2025

Insulin News and Research

Further Reading

Hyaluronidase-1 emerges as a key regulator of postmeal blood sugar

Lipid accumulation levels reveal hidden osteoporosis risk

New approach directly combats the progression of Alzheimer’s and ALS

Adult-onset type 1 diabetes linked to higher cardiovascular and mortality risk

Lipid buildup predicts weaker bones once it passes a critical threshold

Novel Alzheimer's therapy shows low risk of severe side effects

City of Hope opens largest outpatient facility to enhance cancer care

Adverse waist-to-height ratio trajectories during childhood linked to early cardiometabolic risk

GLP-1 receptor agonists improve mood and metabolic health in adults with mental illness

Delayed puberty in boys raises risk of type 2 diabetes later in life, study shows

Mitochondrial transplantation as a strategy to address metabolic decline in aging

Study reveals colonic inflammation as the trigger for beta cell growth in obesity

Trump team faces key legal decision that could put mental health parity in peril

New stem cell model mimics alpha cell behavior in diabetic conditions

Study reveals potential new strategy to prevent or slow progression of Type 1 diabetes

How urine caffeine levels may help detect diabetic eye damage early

Canadian study links ultra processed foods to poor health outcomes

Diabetes drug shows promise for treating prostate cancer

Where and why men die younger: global data breaks it down

Semaglutide clears liver inflammation and cuts fibrosis in MASH patients, trial shows

Lab Matters host Harriet Gould on building a more connected lab community

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

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