Brain News and Research

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The human brain is the center of the human nervous system and is a highly complex organ. Enclosed in the cranium, it has the same general structure as the brains of other mammals, but is over three times as large as the brain of a typical mammal with an equivalent body size.

Microglial states and their impact on Alzheimer's disease

Researchers examined 152,459 microglial transcriptomes from 443 individuals, identifying 12 transcriptional states and their relationship to Alzheimer's disease.

3 Oct 2023

Novel deep learning model to assess Alzheimer's disease progression risk

Patterns in the Alzheimer's disease (AD) trajectory using Mendelian randomization (MR) and deep learning (DL).

3 Oct 2023

Identification of Alzheimer's disease-associated micro-RNA biomarkers through network-based analysis

Micro-ribonucleic acids (miRNAs) linked to cognition and Alzheimer's disease (AD).

3 Oct 2023

How lifestyle tweaks could be the new shield against memory loss: U.S. POINTER study dives in

The U.S. POINTER study aims to explore if lifestyle changes like exercise, diet, and social activities can help preserve cognitive function in older Americans at risk for dementia. Modeled after Finland's successful FINGER study and set to complete in 2025, this extensive research will involve 2,000 participants and focus on diverse and culturally informed strategies.

2 Oct 2023

Eat by the clock: How meal timing tunes your liver's circadian rhythm

A study in Nature Communications delves into how the liver's circadian clock responds to meal timing, impacting fat metabolism and other bodily processes. The research underscores the intricate network that contributes to liver's diurnal rhythms, regulated by protein phosphorylation and nutrient availability.

2 Oct 2023

Compulsive stress coping behaviors linked to brain's dopamine-dependent habit system

Researchers performed longitudinal studies in rats to measure the sensitivity of early established versus compulsive polydipsic alcohol (or water) drinking in response to bilateral infusion of α-flupentixol, anterior dorsolateral striatum (aDLS)-dopamine (DA) receptor antagonist.

2 Oct 2023

Long COVID unmasked: Patients share varied physical, mental, and social challenges

Patient experiences of the post-acute sequelae of coronavirus disease 2019 (COVID-19) or long COVID.

2 Oct 2023

Is long COVID triggering irritable bowel syndrome? Arizona study to investigate

The Arizona CoVHORT research study at the University of Arizona has received $3.2 million in funding to investigate the links between long COVID and gastrointestinal symptoms, specifically irritable bowel syndrome (IBS). Led by epidemiologist Kristen Pogreba-Brown, the study aims to determine how COVID-19 impacts the incidence of IBS, offering potential benefits to millions affected by the ongoing pandemic.

1 Oct 2023

Is play the secret ingredient for your child's brain development?

Dr. Jacqueline Harding's new book, "The Brain that Loves to Play," challenges traditional notions about play and learning, arguing that they are inherently interconnected in early childhood development. Drawing on neuroscience and child development research, the book serves as a practical guide for integrating play into educational and parenting practices for children's long-term well-being.

1 Oct 2023

New drug could transform how doctors treat grade 2 IDH-mutant gliomas

A top UVA Health cancer expert is highlighting how a new drug could transform how doctors treat a brain tumor that typically strikes younger people.

29 Sep 2023

New tau PET radiotracer shows promise for early detection of Alzheimer's disease

A new tau PET radiotracer, 18F-SNFT-1, has been found to be more effective than existing tau PET radiotracers in identifying Alzheimer's disease in its earliest stages, according to research published in the September issue of The Journal of Nuclear Medicine.

29 Sep 2023

Study shows how tumors "hijack" genetic program used by developing nerves

Cancer tumors "hijack" the genetic program used by developing nerves. This is shown in a study by researchers at Umeå University, Sweden.

29 Sep 2023

Meta-analysis reveals how the brain organizes language

Language is the most important tool for human communication and essential for life in our society. "Despite a great deal of neuroscientific research on the representation of language, little is known about the organization of language in the human brain.

29 Sep 2023

New protein identified as substrate for histidine methylation

Proteins are subject to post-translational chemical modifications that result in functional diversity. Methylation is one such modification that is generally believed to occur on lysine and arginine residues.

29 Sep 2023

Cutting-edge NanoSIMS imaging sheds light on the progression of Parkinson's disease

Parkinson's disease is a complex neurodegenerative disorder that leads to the deterioration of specific types of neurons in the brain, resulting in a number of motor and non-motor symptoms.

29 Sep 2023

Parkinson's disease-related neuronal death more likely to occur at night

Disturbances in sleep patterns and the internal biological clock are frequently associated with Parkinson's disease.

29 Sep 2023

Primate model unlocks clues to long-COVID's impact on blood sugar, hints at vaccine benefits

The study uses a non-human primate model to explore the link between long-COVID and disruptions in glucose metabolism, finding a positive correlation. Vaccination appeared to improve glycemic control, suggesting a possible role in managing long-COVID symptoms.

28 Sep 2023

Mobile AI rivals specialists in diagnosing skin cancer, outperforms junior doctors

This multicenter clinical trial compared AI-powered mobile phone diagnostic tools with human medical experts in diagnosing pigmented skin cancer. The study found that the AI system was equivalent to specialists in accuracy and superior to novices, showcasing mobile technology's potential for accessible and accurate skin cancer diagnosis.

28 Sep 2023

Unlocking the code: BigRNA's deep learning model predicts RNA behavior

Researchers have developed BigRNA, a groundbreaking deep learning model capable of predicting RNA behavior, including tissue-specific expression and splicing, directly from genomic DNA sequences. The model excels in identifying pathogenic variants and could be a game-changer in the development of personalized RNA-based therapies for treating genetic diseases.

28 Sep 2023

Loss of brain interneurons linked to cognitive deficits in aging

Normal aging is usually associated with a decline in memory, although it is unclear what factors play a role.

28 Sep 2023

Brain News and Research

Further Reading

Microglial states and their impact on Alzheimer's disease

Novel deep learning model to assess Alzheimer's disease progression risk

Identification of Alzheimer's disease-associated micro-RNA biomarkers through network-based analysis

How lifestyle tweaks could be the new shield against memory loss: U.S. POINTER study dives in

Eat by the clock: How meal timing tunes your liver's circadian rhythm

Compulsive stress coping behaviors linked to brain's dopamine-dependent habit system

Long COVID unmasked: Patients share varied physical, mental, and social challenges

Is long COVID triggering irritable bowel syndrome? Arizona study to investigate

Is play the secret ingredient for your child's brain development?

New drug could transform how doctors treat grade 2 IDH-mutant gliomas

New tau PET radiotracer shows promise for early detection of Alzheimer's disease

Study shows how tumors "hijack" genetic program used by developing nerves

Meta-analysis reveals how the brain organizes language

New protein identified as substrate for histidine methylation

Cutting-edge NanoSIMS imaging sheds light on the progression of Parkinson's disease

Parkinson's disease-related neuronal death more likely to occur at night

Primate model unlocks clues to long-COVID's impact on blood sugar, hints at vaccine benefits

Mobile AI rivals specialists in diagnosing skin cancer, outperforms junior doctors

Unlocking the code: BigRNA's deep learning model predicts RNA behavior

Loss of brain interneurons linked to cognitive deficits in aging

Industry Focus eBook - Neurology/Neuroscience - 2nd edition eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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