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Breast cancer cases and deaths set to surge by 2050—are we prepared?

A global study finds that breast cancer cases will rise by 38% and deaths by 68% by 2050, with the highest incidence in Australia and New Zealand and worsening mortality in low-income countries.

25 Feb 2025

Study reveals ferulic acid's potential in preventing colon cancer

Colon cancer continues to be one of the leading causes of cancer-related deaths worldwide, with poor dietary habits identified as a major risk factor.

25 Feb 2025

Insilico Medicine reaches preclinical milestone in MASH drug discovery

Insilico Medicine("Insilico"), a clinical-stage generative artificial intelligence (AI)-driven drug discovery company, recently achieved preclinical milestone in its collaboration with Therasid Bioscience, a South Korean based biotechnology company focuses on developing innovative first-in-class drugs for treatment for metabolic dysfunction-associated steatohepatitis (MASH).

25 Feb 2025

Women experience perimenopause symptoms much earlier than expected

More than half of women ages 30 to 35 are already suffering moderate to severe symptoms associated with menopause, yet most women are waiting decades before seeking treatment, new research from UVA Health and the Flo women's health app reveals.

25 Feb 2025

Pig kidney transplant patient completes recovery and returns home

Three months after her breakthrough surgery at NYU Langone Health, Towana Looney, the longest-living recipient of a genetically engineered pig kidney, is headed back home to Alabama.

25 Feb 2025

Researchers create mycobacteria with kill switches to improve TB vaccine safety

Working toward more effective tuberculosis (TB) vaccines, researchers at Weill Cornell Medicine have developed two strains of mycobacteria with "kill switches" that can be triggered to stop the bacteria after they activate an immune response.

25 Feb 2025

Early lung cancer diagnosis improved with ctDNA methylation biomarkers

Early diagnosis of lung cancer is a critical priority in clinical practice. It may help reduce the rate of lung-cancer-related mortality, extend disease-free survival, and allow patients to live without ongoing medical interventions and complications.

25 Feb 2025

Review highlights next-generation cancer therapies targeting PIK3CA mutations

A newly published review in Genes & Diseases explores the oncogenic activation of PIK3CA in cancer and highlights emerging targeted therapies designed to improve treatment efficacy while reducing side effects.

25 Feb 2025

New insights into mTOR pathway offer hope for diabetic nephropathy treatment

A newly published study in Genes & Diseases highlights the crucial role of the mammalian target of rapamycin (mTOR) pathway in the progression of diabetic nephropathy (DN) and explores its potential as a therapeutic target.

25 Feb 2025

Routine psychological screening can improve maternal cardiovascular health

Integrating routine psychological health screening and treatment during and after pregnancy may reduce the risk of adverse pregnancy outcomes and improve maternal cardiovascular health, according to a new scientific statement published today in a Go Red for Women spotlight issue of the Journal of the American Heart Association, an open access, peer-reviewed journal of the American Heart Association.

25 Feb 2025

Common medications disrupt brain development by affecting sterol biosynthesis

In a peer-reviewed Perspective (review) article, researchers at the University of Nebraska Medical Center have uncovered concerning evidence that commonly prescribed medications may interfere with crucial brain development processes by disrupting sterol biosynthesis.

25 Feb 2025

Researchers develop new tool to assess psychological impact of esophageal diseases

Psychological factors have a greater impact on the severity of symptoms in esophageal diseases than objective evaluations, such as acid reflux and esophageal motility function. Although there are questionnaires that assess general psychological states in Japan, there were none that were specific to esophageal symptoms.

25 Feb 2025

UCL researchers develop groundbreaking therapy for a common cause of high blood pressure

A minimally invasive therapy that has the potential to transform treatment of a common cause of high blood pressure, has been developed by researchers at UCL, Queen Mary University of London and Barts Health.

25 Feb 2025

Study explores link between antidepressant use and cognitive decline in dementia patients

New research suggests that antidepressants can accelerate cognitive decline in people with dementia. At the same time, some drugs appear to be less harmful than others, which can help doctors make better treatment decisions, according to the study published in BMC Medicine.

25 Feb 2025

Genetic study demonstrates fat-selective weight loss with GLP-1 agonist use

Diabetes and obesity have become pressing health issues worldwide. Glucagon-like peptide-1 (GLP-1) receptor agonists, a class of medications widely used in the treatment of type 2 diabetes (T2D), have shown significant effectiveness in both lowering blood sugar levels and aiding weight loss due to their unique pharmacological mechanisms.

25 Feb 2025

Study challenges role of BRCA1 mutation in prostate cancer initiation

Mutations in the BRCA1 gene that are either inherited (germline) or acquired (somatic) might not be key to the initiation of prostate cancer, as previously thought, suggests the first study of its kind, published online in the open access journal BMJ Oncology.

24 Feb 2025

What can bears, tardigrades, and worms teach us about surviving deep space?

Scientists are exploring how animal models—hibernators, extremophiles, and small organisms—can help counteract the health risks of long-duration space travel, using AI-driven monitoring to translate these findings into astronaut solutions.

24 Feb 2025

Researchers uncover a surprising layer of complexity in aldosterone-producing tumors

Kyushu University researchers have uncovered a surprising layer of complexity in aldosterone-producing adenomas (APAs)-adrenal gland tumors that drive high blood pressure.

24 Feb 2025

Machine learning algorithm decodes immune system’s hidden data for disease detection

Your immune system harbors a lifetime's worth of information about threats it's encountered - a biological Rolodex of baddies.

24 Feb 2025

New imaging tool reveals the brain's role in cochlea sensitivity

The brain may play a role in helping the ear regulate its sensitivity to sound and compensate for hearing loss by sending a signal to a structure in the inner ear known as the cochlea, according to a study that was just published in the Journal of Neuroscience.

24 Feb 2025