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Unlocking the potential of double negative memory B cells in cancer treatment

University of Pittsburgh School of Medicine and UPMC Hillman Cancer Center scientists have discovered a novel subset of cancer-fighting immune cells that reside outside of their normal neighborhood – known as the tertiary lymphoid structure – where they become frustratingly dysfunctional when in close contact with tumors.

19 Feb 2025

Innovative method improves understanding of cellular and molecular mechanisms in kidney diseases

Researchers have demonstrated the feasibility of a morphological-based approach to interpreting spatial transcriptomic (ST) data, helping to improve understanding of the lesions that occur in chronic kidney disease (CKD), at both the cellular and molecular levels.

19 Feb 2025

New AI approach set to revolutionize ECG data interpretation in heart disease diagnosis

A team of researchers from Tsinghua University and Beijing Tsinghua Changgung Hospital has introduced a cutting-edge method to improve the interpretation of electrocardiogram (ECG) data.

19 Feb 2025

Newly discovered antigens could speed the development of potent cancer immunotherapies

Immune therapy has transformed how cancer is treated, but many tumors continue to evade these treatments, thanks to their resemblance to healthy tissue.

19 Feb 2025

Standardized goals of care note enhances communication in healthcare

It is important that a healthcare team is aware of and understands a patient's goals of care, both medical and personal.

19 Feb 2025

New HIV therapy lenacapavir shows high efficacy in Ugandan population

A multi-national, multi-institutional study led by Weill Cornell Medicine investigators found little natural resistance to a new HIV therapy called lenacapavir in a population of patients in Uganda.

19 Feb 2025

Simple text-messaging system saves time for cancer patients during treatment visits

Cancer patients spend a lot of time on their care. Meeting with doctors and other members of their health care team, getting labs and other tests, picking up prescriptions, and undergoing treatment all takes time.

19 Feb 2025

Ginger's furanodienone compound may offer new treatment for inflammatory bowel disease

An international team led by researchers at the University of Toronto has found a compound in ginger, called furanodienone (FDN), that selectively binds to and regulates a nuclear receptor involved in inflammatory bowel disease (IBD).

19 Feb 2025

Tampere University licenses drug for Epidermolysis Bullosa to Theravia

Tampere University has licensed a drug molecule intended for treating Epidermolysis Bullosa (EB), a group of rare and severe skin disorders, to Theravia, a pharmaceutical company headquartered in the Paris region of France.

19 Feb 2025

Infant exposure to herpes virus may cause memory problems later in life

Very early exposure to even a very small dose of herpes simplex virus (HSV) in infant mice can lead to cognitive decline later in life, according to findings from a new Dartmouth-led study, in collaboration with Harvard Medical School and published in the journal PLoS Pathogens.

19 Feb 2025

Hydrodissection may offer hope for post-amputation pain relief

A reliable method to treat post-amputation pain remains elusive, but a new Northwestern Medicine study conducted in collaboration with Ukrainian physicians suggests that hydrodissection - a simple procedure that injects fluid around nerves - may reduce residual limb pain and opioid dependence.

19 Feb 2025

Vitamin E supplementation may reduce food allergy development in newborns

New research found that supplementing maternal diet with α-tocopherol, a form of vitamin E, can reduce the development of food allergy and anaphylaxis in newborn mice.

19 Feb 2025

Older adults and women more likely to develop postoperative infections after heart surgery

One in five older adults gets an infection up to six months after heart surgery - with women far more likely to develop one, according to studies led by Michigan Medicine.

19 Feb 2025

Lifestyle and environmental factors play bigger role in health and premature death than genetics

A new study led by researchers from Oxford Population Health has shown that a range of environmental factors, including lifestyle (smoking and physical activity), and living conditions, have a greater impact on health and premature death than our genes.

19 Feb 2025

New mRNA technique targets disease cells while sparing healthy ones

Imagine a breakthrough in cancer treatment where only malignant cells are targeted, sparing healthy host cells; or patients with abnormal protein synthesis are treated to produce a healthy protein.

19 Feb 2025

Neonatal seizures linked to higher risk of epilepsy in children

Seizures in newborns are one of the most frequent acute neurological conditions among infants admitted to neonatal care units.

19 Feb 2025

Preventing colorectal cancer through lifestyle choices

The evidence is clear - screening for colorectal cancer may save one's life. Today, more and more people are choosing colorectal cancer screening. As a result, there is a steady decline in the number of older people getting and dying from colorectal cancer. Lower rates of smoking among Americans have also contributed to the decline in the past several years.

19 Feb 2025

Plant immune responses may offer insights into human brain diseases

A groundbreaking study led by a team of researchers at the University of Kentucky's Martin-Gatton College of Agriculture, Food and Environment has revealed a surprising biochemical connection between plant immune responses and human neurological health.

19 Feb 2025

Direct connection found between memory and sensory processing centers in brain

A newly identified part of a brain circuit mixes sensory information, memories, and emotions to tell whether things are familiar or new—and important or just "background noise."

19 Feb 2025

Recreational exercise, not work activity, linked to lower type 2 diabetes risk

Researchers have found that engaging in moderate to vigorous physical activity during leisure time, regardless of occupational physical activity, is associated with a reduced risk of type 2 diabetes. A combination of sedentary leisure-time activity and demanding occupational activity may increase the risk.

19 Feb 2025