Proteomics News and Research

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The term 'proteome' was first coined in 1994, and refers to all the proteins in a cell, tissue, or organism. Proteomics refers to the study of the proteome. Because proteins are involved in almost all biological activities, the proteome is a rich source of biological information.

Bone proteomics could estimate the time of death for corpses found in water

When a dead body is found, one of the first things a forensic pathologist tries to do is estimate the time of death.

29 Apr 2020

Albany, Wisconsin researchers look for molecular clues to fight COVID-19

In the center of the COVID-19 pandemic, hospitals are racing to maintain quality care for patients with severe disease while facing a shortage of resources and limited understanding of the novel coronavirus.

28 Apr 2020

Gustave Roussy and Biognosys Announce Partnership

The severe pneumonitis in patients infected by SARS-Cov-2 requires prolonged treatment in intensive care units with mechanical ventilation.

From Biognosys 28 Apr 2020

Caprion - HistoGeneX Expands its biomarker capabilities and deploys molecular COVID-19 testing services

Caprion - HistoGeneX announced today that the company is launching a molecular PCR testing service for identifying patients with COVID-19.

28 Apr 2020

Gut microbiota could predict severity of COVID-19

The COVID-19 pandemic is spreading to every corner of the world. But not everyone is falling sick at the same rate. A new study published on the preprint server medRxiv in April 2020 suggests that the composition of the gut microbiome could partially explain the difference in susceptibility. This adds a new dimension to what is currently known about the disease.

27 Apr 2020

Scientists identify new biomarker to detect subclinical atherosclerosis

Scientists at the Centro Nacional de Investigaciones Cardiovasculares and the Instituto de Investigación Sanitaria-Fundación Jiménez Díaz in Madrid have demonstrated that a proteins present in early atheroma plaques--accumulations of cholesterol in the wall of arteries--could be used as a biomarker to detect atherosclerosis in the subclinical phase, before the appearance of symptoms.

21 Apr 2020

Technologies converge on interacting surfaces in protein complexes

Researchers have fine-tuned a method to pinpoint surfaces within interacting large multi-protein complexes.

14 Apr 2020

Combining Improved Ion Usage Efficiency with Data Independent Acquisition to Quantify Proteomes

In this interview, Dr. Ben Collins, Reader from the School of Biological Sciences, Queen’s University Belfast talks to News-Medical Life Sciences about his research and work into diaPASEF workflow.

From Bruker Daltonics 8 Apr 2020

New family of molecules to join altered receptors in Alzheimer's, Parkinson's and Huntington's

An article published in the Journal of Medicinal Chemistry shows a new family of molecules with high affinity to join imidazoline receptors, which are altered in the brain of those patients with neurodegenerative diseases such as Alzheimer's, Parkinson's and Huntington's.

3 Apr 2020

Investigating Human Disease with Mass Spectrometry-based Proteomics

Dr. Andrew Webb describes how his lab uses mass spectrometry-based techniques to understand the role of post-translational modifications in human disease.

From Bruker Daltonics 3 Apr 2020

Duke to lead PCORI-funded study of COVID-19 prevention in healthcare workers

The Patient-Centered Outcomes Research Institute has funded up to $50 million to evaluate hydroxychloroquine (HCQ) as a preventive drug for the novel coronavirus.

1 Apr 2020

Lance Liotta receives $72,000 for collaborative project

Lance Liotta, Co-Director, Applied Proteomics and Molecular Medicine, received $72,000 from Queensland University of Technology for the project: "The Systems Biochemistry of Adaptation in Cellular Protein Networks." Australian Research Council Future Fellowship (total $784,680).

22 Mar 2020

Fish consumption during pregnancy associated with improved metabolic health of children

To eat or not to eat fish is a question that has long concerned pregnant women. Now, a new USC study shows that children whose mothers ate fish from one to three times a week during pregnancy were more likely to have a better metabolic profile -- despite the risk of exposure to mercury -- than children whose mothers ate fish rarely (less than once a week).

16 Mar 2020

Popular painkiller may have more significant effects on the liver than expected

The popular painkiller ibuprofen may have more significant effects on the liver than previously thought, according to new research from the University of California, Davis.

11 Mar 2020

Diet influences multiple sclerosis disease course

The short-chain fatty acid propionic acid influences the intestine-mediated immune regulation in people with multiple sclerosis (MS).

11 Mar 2020

Breakthrough technology identifies proteins' nearest neighbors on cell surfaces

When corporate partners in the Princeton Catalysis Initiative sat down two years ago with David MacMillan, they presented him with a biological challenge at the heart of potential cancer medicines and other therapeutics: which proteins on a cell's surface touch each other?

5 Mar 2020

New research cluster aims to use mass spectrometry to provide insights in systems medicine

The Mainz University Medical Center and Johannes Gutenberg University Mainz are establishing the interdisciplinary research cluster entitled "Data-Independent Acquisition-based Systems Medicine (DIASyM): Mass Spectrometry for High-Throughput Deep Phenotyping of Heart Failure Syndrome".

28 Feb 2020

Molecular study defines the contributions of key genes, proteins to endometrial cancer

The most comprehensive molecular study of endometrial cancer to date has further defined the contributions of key genes and proteins to the disease, say its authors.

13 Feb 2020

Indivumed and Biognosys partnership aims to enhance proteomics insights

Indivumed, a physician-led, integrated global oncology solution provider, announced its partnership with Biognosys.

From Biognosys 4 Feb 2020

Researchers create new brain cancer model using genetically engineered pluripotent stem cells

Using genetically engineered human pluripotent stem cells, University of California San Diego School of Medicine researchers created a new type of cancer model to study in vivo how glioblastoma, the most common and aggressive form of brain cancer, develops and changes over time.

29 Jan 2020