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NIH awards $3.9 million grant to develop a non-opioid pain treatment

The National Institute of Neurological Disorders and Stroke, part of the National Institutes of Health (NIH), has awarded a $3.9 million grant to a multi-institutional team led by scientists at Sanford Burnham Prebys Medical Discovery Institute to develop a non-opioid pain therapeutic and advance it into a Phase 1 clinical trial.

4 May 2026

Advanced AI models outperform pediatricians in diagnosing rare diseases

Artificial intelligence (AI) is increasingly being explored as a tool to support clinical decision-making, yet its real-world performance in pediatric diagnosis remains unclear.

4 May 2026

NIH grant fuels NYU Langone efforts to accelerate medical research discoveries

NYU Langone Health has been awarded a nearly $70 million, seven-year renewal grant from the National Institutes of Health (NIH) to fund its Clinical and Translational Science Institute (CTSI). The award is the highest level of funding available nationally under NIH's Clinical and Translational Science Awards (CTSA) Program.

4 May 2026

Cranberry juice may boost antibiotic effectiveness against urinary infections

More than 400 million people experience a urinary tract infection every year, and some epidemiological studies estimate that more than half of all women will develop at least one in their lifetime.

4 May 2026

Scientists find that human embryos are vulnerable to COVID

A University of California, Riverside study reports that cells in the earliest stages of human development could be susceptible to infection by SARS-CoV-2, which causes COVID-19, offering new insight into how the virus interacts with developing human tissues and why that may matter for pregnancy research.

4 May 2026

New tools for quicker and easier Mpox diagnosis

Following the rise in monkeypox (Mpox) cases, particularly in countries where the disease had not traditionally been observed, the World Health Organization (WHO) declared a Public Health Emergency of International Concern in June 2022 and again in August 2024.

4 May 2026

Identifying the ages when Alzheimer’s biomarkers sharply change

New research identifies critical ages for Alzheimer's biomarkers, enhancing screening strategies and understanding neurodegeneration across the aging spectrum.

1 May 2026

Pretargeted radioimmunotherapy shows promise for colorectal cancer treatment

A new pretargeted radioimmunotherapy (PRIT) technique has been shown to be safe and effective in eradicating tumors from a preclinical colorectal cancer model.

30 Apr 2026

New CAR T cell design boosts persistence and reduces toxicity

CAR T-cell therapy has transformed the treatment of hematologic malignancies, yet many patients do not achieve lasting benefit – often because the infused cells fail to expand or persist.

30 Apr 2026

Cryo-electron microscopy offers an unprecedented view of gene transcription

The enzyme RNA polymerase (RNAP) carries out transcription, copying DNA into RNA. It's the first step in gene expression, and a process fundamental to all life.

30 Apr 2026

Study shows eIF4G2 gene maintains adult intestinal stem cell identity

Years before he conducted the research that would earn him a Nobel Prize in Physiology and Medicine, Shinya Yamanaka, MD, PhD, was a postdoctoral scientist at Gladstone Institutes, studying genes.

30 Apr 2026

Portable MiniDock MTB delivers tuberculosis results in thirty minutes

Drugs to treat tuberculosis have been around for more than 75 years, yet it remains the world's top infectious disease killer.

30 Apr 2026

Scientists discover a potential new way to slow ALS disease progression

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease that causes the progressive loss of motor neurons, which in most cases leads to respiratory failure within three to five years after diagnosis.

30 Apr 2026

AI and CRISPR technologies drive proactive health monitoring

JMIR Publications today featured two new stories in its News and Perspectives section, highlighting a shift toward proactive, tech-integrated health monitoring.

30 Apr 2026

DeNovix launches Squid™ Full Range Pipette: A single device covering 1 – 1000 µL

DeNovix Inc. has introduced a new product to their innovative collection of life science devices—the Squid™ Full Range Pipette.

From DeNovix Inc. 30 Apr 2026

Metabolic rewiring could help CAR-T cells fight solid tumors

This review explains how glucose scarcity, lipid disruption, amino acid deprivation, and toxic metabolites weaken CAR-T cells inside solid tumors. It highlights metabolic reprogramming as a promising strategy to improve CAR-T cell persistence, adaptability, and anti-tumor function.

29 Apr 2026

How multi-omics is changing what scientists can see in the human immune system

Human systems immunology is using multi-omics, single-cell tools, spatial technologies, and AI to decode immune responses across real-world human cohorts. The review highlights major opportunities for biomarker discovery and precision medicine, while stressing the need for rigorous study design, validation, and careful interpretation.

29 Apr 2026

Brief walking breaks help the body control sugar after carb-rich meals

Brief brisk walking breaks during prolonged sitting improved post-meal interstitial glucose responses in healthy adults after carbohydrate-rich meals, with the strongest effects seen in women. Gluteal fat showed a more stable glucose pattern than abdominal fat, suggesting it may help buffer carbohydrate-related glucose rises through depot-specific uptake and lipid-synthesis pathways.

29 Apr 2026

Researchers use light-activated nanozymes to treat aggressive brain tumors

Brain tumors cannot always be successfully treated with conventional therapies. A team from Empa and the hospital network HOCH Health Ostschweiz is therefore developing nanozymes that can attack cancer cells directly in the brain during tumor surgery.

29 Apr 2026

New genetic risk test estimates inherited risk for cardiovascular conditions

Researchers at Mass General Brigham Heart and Vascular Institute and collaborators have developed and validated a new genetic risk test that can estimate a person's inherited risk for eight common cardiovascular conditions, offering a more comprehensive approach to prevention.

29 Apr 2026