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New clinical trial aims to extend survival for bile duct cancer patients

A new clinical trial, sponsored by UCL and UCLH, aims to extend survival for some patients with cancer in the biliary tract by treating them with therapies specifically tailored to the genetic profile of their tumor.

17 Jan 2025

Inflammasome proteins found to prevent cancer by regulating stem cells

A group of immune proteins called the inflammasome can help prevent blood stem cells from becoming malignant by removing certain receptors from their surfaces and blocking cancer gene activity, according to a preclinical study by Weill Cornell Medicine investigators.

17 Jan 2025

Over 500 European patients diagnosed through groundbreaking genetic research

More than 500 European patients with unknown conditions have received a diagnosis through new genetic research.

17 Jan 2025

Early brain changes in Huntington’s disease detected two decades before symptoms

Subtle changes in the brain, detectable through advanced imaging, blood and spinal fluid analysis, happen approximately twenty years before a clinical motor diagnosis in people with Huntington's disease, finds a new study led by UCL researchers.

17 Jan 2025

Junk food turns public villain as power shifts in Washington

The new Trump administration could be coming for your snacks. For years, the federal government has steered clear of regulating junk food, fast food, and ultra-processed food.

17 Jan 2025

Triple-drug chemo fails to improve survival in advanced biliary tract cancer

The results of a clinical trial led by researchers at the University of Arizona Health Sciences and published in the Journal of Clinical Oncology showed that chemotherapy combining three different types of drugs did not improve overall survival for patients with advanced stage, inoperable biliary tract cancers.

17 Jan 2025

Swedish study demonstrates significant reduction in infant mortality after 41 weeks gestation

The proportion of babies dying before and during labor after 41 weeks of gestation has fallen by 47% in Sweden in a relatively short time. This is the result of a major national study. The reduction has occurred since the procedures around induction have changed.

17 Jan 2025

Unveiling the metabolic pathways of Fusobacterium nucleatum in OSCC

A recent study has made significant strides in uncovering how the oral microbiome, particularly the bacterium Fusobacterium nucleatum, plays a crucial role in the progression of oral squamous cell carcinoma (OSCC). By identifying key interactions between this common oral bacterium and host cells, the research has unveiled important metabolic pathways and mechanisms that may serve as potential therapeutic targets.

17 Jan 2025

New approach shows promise in fighting multiple cancers

The tissue adjacent to a tumor behaves differently than areas farther away: The tumor's cancerous cells influence their surroundings, blocking the body's immune defenses and creating a sort of haven in which the tumor can grow. Treatments that target some of these pro-tumor actions are effective in a number of cancers, but only for some patients; in others, these treatments have little effect.

17 Jan 2025

AI deciphers intracellular signals from extracellular recordings in heart cells

A team of researchers led by the University of California San Diego and Stanford University has developed a noninvasive method to monitor the electrical activity inside heart muscle cells from the outside, avoiding the need to physically penetrate the cells.

16 Jan 2025

Brain stimulation enables nuanced feeling in prosthetic hands

You can probably complete an amazing number of tasks with your hands without looking at them. But if you put on gloves that muffle your sense of touch, many of those simple tasks become frustrating. Take away proprioception - your ability to sense your body's relative position and movement - and you might even end up breaking an object or injuring yourself.

16 Jan 2025

COVID-19 dramatically raises the risk of developing ME/CFS

Study highlights a fourfold increase in ME/CFS risk among COVID-19 patients, with 89% of post-COVID ME/CFS cases overlapping with severe long COVID symptom clusters.

16 Jan 2025

Androgen clock reveals how hormones shape aging and health

Scientists unveil the androgen clock, a precise epigenetic tool to measure long-term androgen exposure and its role in aging and health.

16 Jan 2025

NIMH awards $1.5 million grant for long COVID neurological research

The National Institute of Mental Health has awarded a significant grant of $1.5 million to Jianyang Du, PhD, of the University of Tennessee Health Science Center, for a research study aimed at uncovering the cellular and molecular mechanisms that lead to neurological disorders caused by long COVID-19.

16 Jan 2025

Measles risk heightened by undernutrition in vulnerable children

Amid a global surge in measles cases, new research suggests that undernutrition may be exacerbating outbreaks in areas suffering from food insecurity.

16 Jan 2025

Majority of naloxone recipients in NYC at high risk of overdose

The overwhelming majority of those in New York City who obtained a naloxone kit to counteract opioid overdose had a high need for the drug, according to a new study by Weill Cornell Medicine investigators and the New York City Department of Health and Mental Hygiene.

16 Jan 2025

Scientists discover new mechanism behind Huntington’s disease brain cell death

Scientists at the Broad Institute of MIT and Harvard, Harvard Medical School, and McLean Hospital have discovered a surprising mechanism by which the inherited genetic mutation known to cause Huntington's disease leads to the death of brain cells.

16 Jan 2025

New resource from NCCN offers guidance on hereditary cancer risk

Today, the National Comprehensive Cancer Network (NCCN)-an alliance of leading cancer centers-published a new resource to inform people about the latest recommendations around hereditary and familial cancer risk.

16 Jan 2025

Immune system changes may predict antipsychotic resistance in schizophrenia Scientis...

Researchers from the National Healthcare Group (NHG)'s Institute of Mental Health (IMH) and Agency for Science, Technology and Research (A*STAR) have made strides in understanding the connection between the immune system and resistance to antipsychotic medications in schizophrenia, using changes in immune cell populations to predict potential treatment resistance and initiate the most appropriate treatment sooner.

16 Jan 2025

Wearable devices can identify and predict flare-ups in inflammatory bowel disease

Wearable devices can identify, differentiate, and predict flare-ups, or the worsening of symptoms and inflammation, in inflammatory bowel disease (IBD), Mount Sinai researchers have shown in a first-of-its-kind study.

16 Jan 2025