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Research finds persistent prescribing of risky medications to older adults with dementia

Despite years of clinical guidelines warning against the practice, one in four Medicare beneficiaries with dementia is prescribed brain-altering medications linked to falls, confusion, and hospitalization, according to new research to be published January 12 in the peer-reviewed journal JAMA.

12 Jan 2026

Gene regulators could restore the aging body's ability to self-repair

As we age, we don't recover from injury or illness like we did when we were young. But new research from UCSF has found gene regulators - proteins that turn genes on and off - that could restore the aging body's ability to self-repair.

12 Jan 2026

Researchers identify possible target for new therapies against periodontitis aggravated by smoking

Smoking tobacco is known to worsen symptoms of periodontitis and reduce responsiveness to treatment. Using high-resolution spatial transcriptomics, researchers identified differences between smokers and non-smokers in the expression of genes that weaken gum epithelial integrity and cause bone damage through inflammation.

12 Jan 2026

Heavy coffee drinking may weaken bone density in older women

Researchers investigate the longitudinal associations of coffee and tea consumption with bone mineral density in older women.

12 Jan 2026

Chronic back pain predicts poor sleep in older men

Researchers investigate the prevalence of back pain and sleep issues in men 65 years of age and older.

12 Jan 2026

$Neural pain pathways found to play crucial role in bone fracture healing$

Neural pain pathways found to play crucial role in bone fracture healing

When a house catches on fire, we assume that a smoke alarm inside will serve one purpose and one purpose only: warn the occupants of danger.

8 Jan 2026

ICSA 2025: Infection's role in cellular senescence, inflammation, and aging

A new meeting report was published in Volume 17, Issue 12 of Aging-US on December 23, 2025, titled "Cellular senescence meets infection: highlights from the 10th annual International Cell Senescence Association (ICSA) conference, Rome 2025."

8 Jan 2026

Reproductive history is associated with women's lifespan and biological aging

A study based on Finnish twins shows that reproductive history is associated, at the population level, with women's lifespan and biological aging.

8 Jan 2026

Solving the home care quandary

You're ready to leave the hospital, but you don't feel able to care for yourself at home yet.

8 Jan 2026

Newly discovered molecules accelerate the removal of immune-modulating enzyme

Cells have a remarkable housekeeping system: proteins that are no longer needed, defective, or potentially harmful are labeled with a molecular "tag" and dismantled in the cellular recycling machinery.

7 Jan 2026

Blood biomarkers predict risk of multimorbidity in older adults

A small set of common blood biomarkers predicts which older adults will develop specific combinations of chronic diseases - and how quickly, a new study from Karolinska Institutet published in Nature Medicine reports.

7 Jan 2026

Microglia help protect the spinal cord from age-related damage

Researchers at Karolinska Institutet have discovered that the nervous system's own immune cells help protect the spinal cord from age-related damage.

7 Jan 2026

Homeless shelters for seniors pop up, catering to older adults’ medical needs

Just outside Salt Lake City sits an old, two-story, brick hotel. It's been given new life as a homeless shelter for seniors. The Medically Vulnerable People shelter — or MVP shelter, as it's known — is for people 62 and older or for younger adults with chronic health issues.

7 Jan 2026

Charting brain cell epigenomics to reveal origins of psychiatric disorders

In a revealing Genomic Press Interview published today in Genomic Psychiatry, Dr. Maria Margarita Behrens recounts an extraordinary scientific journey that wound through four countries and multiple disciplines before arriving at fundamental questions about how the brain develops and what goes wrong in psychiatric disorders.

6 Jan 2026

Chronic back pain linked to future sleep problems in older men

About half of older men suffer from sleep problems, back pain or both, according to Soomi Lee, associate professor of human development and family studies at Penn State.

6 Jan 2026

Simple drug treatments could help older brains cope with memory decline and postoperative recovery

Simple pharmaceutical interventions could help older brains cope with memory impairment and recovery after surgery, new studies in mice suggest.

6 Jan 2026

Neighborhood deprivation predicts poorer lower-limb strength

Neighborhood-level disadvantages are linked to reduced lower limb strength and mobility in older adults, emphasizing the need for targeted interventions.

6 Jan 2026

New exercise-sensing pathway offers hope for osteoporosis treatment

A research team from the Department of Medicine, School of Clinical Medicine, LKS Faculty of Medicine at the University of Hong Kong (HKUMed) has uncovered a key biological mechanism that explains how exercise maintain strong bones, paving the way for novel treatments for osteoporosis and bone loss in people who are unable to engage.

6 Jan 2026

"Blue zones" longevity claims validated by new research

A new peer-reviewed paper published in The Gerontologist provides the most comprehensive scientific response to date addressing recent critiques of the so-called "blue zones," regions of the world known for unusually high concentrations of people living long, healthy lives.

5 Jan 2026

RNA splicing and processing genes emerge as central drivers of aging across tissues

A new research paper featured as the cover of Volume 17, Issue 12 of Aging-US was published on December 22, 2025, titled "A combination of differential expression and network connectivity analyses identifies a common set of RNA splicing and processing genes altered with age across human tissues."

5 Jan 2026