Pathology News and Research

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Pathology is the study and diagnosis of disease through examination of organs, tissues, bodily fluids, and whole bodies (autopsies). The term also encompasses the related scientific study of disease processes, called General pathology. Medical pathology is divided in two main branches, Anatomical pathology and Clinical pathology. Veterinary pathology is concerned with animal disease whereas Phytopathology is the study of plant diseases.

Scientists pinpoint metabolic failure as the cause of muscle loss in aging

A multi-omics study reveals that impaired branched-chain amino acid (BCAA) catabolism is a key driver of sarcopenia, suggesting it as a potential therapeutic target.

17 Feb 2025

Lecanemab and donanemab slow Alzheimer’s decline, but is the benefit worth the cost?

Study finds that disease-modifying therapies for Alzheimer’s, lecanemab and donanemab, can extend independence in daily activities by up to 13 months, though their clinical relevance remains debated.

17 Feb 2025

Researchers uncover cause of persistent blood clots despite treatment

A team of researchers have made a new discovery in the field of hematology, providing an explanation for spontaneous and unusual blood-clotting that continues to occur despite treatment with full-dose blood thinners.

14 Feb 2025

Researchers discover genetic mutation linked to toxic protein buildup in Alzheimer's

The root causes of most forms of Alzheimer's disease largely remain a mystery. Now, researchers have revealed a new piece of the puzzle.

13 Feb 2025

Enzyme found in lymphatic cells enhances immune activity against tumors

When a tumor develops, it creates a structure around itself called the tumor stroma, within which blood and lymphatic vessels ensure nutritional and respiratory biological exchanges.

13 Feb 2025

Study uncovers how MAGE-4 and Pten loss promote aggressive tumor growth

A study published in Science Advances reveals a novel strategy that allows tumors to evade the body's immune response critical for their elimination.

12 Feb 2025

McMaster University researchers discover new blood clotting disorder

Researchers at McMaster University have made a groundbreaking discovery in the field of hematology, providing an explanation for spontaneous and unusual blood-clotting that continues to occur despite treatment with full-dose blood thinners.

12 Feb 2025

Long-term yogurt intake linked to reduced risk of colorectal cancer

Yogurt, which contains live strains of bacteria, is thought to protect against many types of diseases, with some reports indicating it could reduce risk of colorectal cancer.

12 Feb 2025

UCLA study reveals key role of mismatch repair genes in Huntington’s disease

A new UCLA Health study has discovered in mouse models that genes associated with repairing mismatched DNA are critical in eliciting damages to neurons that are most vulnerable in Huntington's disease and triggering downstream pathologies and motor impairment, shedding light on disease mechanisms and potential new ways to develop therapies.

11 Feb 2025

Alzheimer’s escape: How one man defied his genetic fate for nearly two decades

A groundbreaking study reveals how a rare combination of genetics, proteomics, and environmental factors may hold the key to delaying or preventing Alzheimer's, challenging long-held assumptions about the disease.

11 Feb 2025

Study explores why newborns regenerate heart tissue better than adults

Newborns with heart complications can rely on their newly developed immune systems to regenerate cardiac tissues, but adults aren't so lucky.

11 Feb 2025

Breakthrough discovery on tau protein opens new paths for Alzheimer’s drug development

A complementary drug to combat Alzheimer's disease could target a specific part of the nerve cell protein tau.

11 Feb 2025

Novel biomarker for early prevention of Alzheimer’s disease

New serine biomarkers show promise for early Alzheimer's detection, linking tau assemblies to cognitive decline and offering potential for timely intervention.

11 Feb 2025

Study uncovers potential target for treating keloid scars

Keloids are fibrotic scars that extend beyond the boundaries of the original wound, often causing physical disfigurement and emotional distress.

10 Feb 2025

New biomarker test detects early tau tangles in Alzheimer's disease

Years before tau tangles show up in brain scans of patients with Alzheimer's disease, a biomarker test developed at the University of Pittsburgh School of Medicine can detect small amounts of the clumping-prone tau protein and its misfolded pathological forms that litter the brain, cerebrospinal fluid and potentially blood, new research published today in Nature Medicine suggests.

10 Feb 2025

International travel and health care networks drive Candida auris outbreaks

In just a decade, the drug-resistant fungal pathogen Candida auris (C. auris) has emerged as one of the most formidable threats to health care settings worldwide.

10 Feb 2025

MaxCyte® acquires SeQure Dx to broaden cell engineering offerings with on-target and off-target editing assessments

MaxCyte, Inc., a leading, cell-engineering focused company providing solutions to advance the discovery, development and commercialization of next-generation cell therapeutics announced today the acquisition of SeQure Dx, a market leader of on-target and off-target editing assessment services for cell and gene therapies.

From MaxCyte, Inc. 6 Feb 2025

New nasal vaccine for COVID-19 set to begin clinical trial in the U.S.

A nasal vaccine for COVID-19 – based on technology developed at Washington University in St. Louis – is poised to enter a phase 1 clinical trial in the U.S. after an investigational new drug application from Ocugen, Inc. was approved by the Food and Drug Administration (FDA). Ocugen, a U.S.-based biotechnology company, licensed the innovative technology from WashU in 2022.

5 Feb 2025

Experimental drug shows promise in restoring memory in Alzheimer's model

A paradigm-shifting study from the Centre for Addiction and Mental Health (CAMH) shows an experimental drug, GL-II-73, has the potential to restore memory and cognitive function in a mouse model of Alzheimer's disease.

4 Feb 2025