Respiratory News and Research

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COVID-19 and the gut-lung axis

A new study explores the hypothesis that stimulation of the gut could be responsible for the lung inflammation seen in COVID-19, triggered by SARS-CoV-2.

16 Sep 2021

Live oral SARS-CoV-2 vaccine provides partial protection in Rhesus Macaques

A new study describes the partial protection against respiratory infection with SARS-CoV-2 following gut inoculation with a live attenuated virus.

16 Sep 2021

IL-1-Ra autoantibodies observed in high frequency in children with PIMS/MIS-C

Although severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection typically affects children only mildly, multisystem inflammatory syndrome in children (MIS-C) or pediatric inflammatory multisystem syndrome (PIMS) is a serious but rare complication occurring after infection.

16 Sep 2021

New modeling on efficacy of BioNTech-Pfizer's SARS-CoV-2 vaccine against variants

In order to address these issues, scientists from Xitific LTD and IDEAPharma in the UK proposed a novel approach to the framework of immune correlates, built upon the previous research. The framework formulated by the authors was developed for the mRNA-based vaccinations but could be applied to the other variations.

16 Sep 2021

Therapeutic potential of clinical-grade ACE2 for blocking SARS-CoV-2 variants

According to new research by an international team of scientists, all SARS-CoV-2 variants, including variants of concern (VOC) Alpha, Beta, Gamma, and Delta, exhibit enhanced affinity toward recombinant human soluble ACE2.

16 Sep 2021

This 3D modeling reveals how SARS-CoV-2 attacks

Now, researchers at the Garvan Institute of Medical Research, Darlinghurst in Australia, CSIRO Data61, and the School of Biotechnology and Biomolecular Sciences (UNSW) demonstrated the most comprehensive analysis of the three-dimensional structure of SARS-CoV-2, providing a new insight into how the virus infects cells and replicates.

16 Sep 2021

Grants to promote COVID-19 vaccination among people with intellectual and developmental disabilities

Patients with intellectual and developmental disabilities (IDD) are three times more likely to die from COVID-19 than the general population. Their heightened risk is due to a variety of causes: pre-existing health conditions, such as respiratory problems or obesity; increased likelihood of living in group homes, taking shared transportation, and being exposed to people outside their households; and struggles with safety precautions like mask-wearing or social distancing.

16 Sep 2021

Pfizer-BioNTech’s COVID-19 vaccine proves effective against recent SARS-CoV-2 variants

Researchers in the United States and Germany have conducted a study showing that the Pfizer-BioNTech vaccine designed to protect against coronavirus disease 2019 (COVID-19) is effective against recently emerged variants of severe acute respiratory syndrome coronavirus 2 (SARS-Cov-2).

16 Sep 2021

Link identified between early lower respiratory tract infections and development of OSA in children

Several birth cohorts have defined the pivotal role of early lower respiratory tract infections (LRTI) in the inception of pediatric respiratory conditions.

15 Sep 2021

Analysis of the immune landscape in mild-to-moderate COVID-19

A new study includes an analysis of plasma cytokine levels, peripheral blood immune cell composition, and SARS-CoV-2 specific Igs in COVID-19.

15 Sep 2021

Flavonoids can potentially help prevent COVID-19-induced diarrhea, study finds

A recent study published in Tropical Biomedicine determines whether flavonoids can help prevent diarrhea caused by SARS-CoV-2 infection.

15 Sep 2021

Study looks at exposure to different SARS-CoV-2 variants and immune response

Researchers compared the responses against several SARS-CoV-2 VoCs in sera from individuals exposed to variant infection, vaccination, or both.

15 Sep 2021

For My Lung Health campaign wins 2021 Pharmaceutical Executive APEX Awards

For My Lung Health, the joint American Thoracic Society and American College of Chest Physicians (CHEST) campaign, is the winner of this year's Pharmaceutical Executive APEX Awards in the respiratory category.

15 Sep 2021

COVID mRNA vaccines display weakened immune response with age and diminish over time, according to new study

Researchers from Simon Fraser University in Canada decided to investigate the magnitude of immunity in mRNA vaccines for COVID-19.

15 Sep 2021

Phase I trial investigates using antiparasitic nitazoxanide for treatment of COVID-19

In a recent study, researchers investigate the possibility of using the thiazolide antiparasitic nitazoxanide for the treatment of COVID-19.

15 Sep 2021

Researchers quantify the risk of children suffering severe outcomes from malaria

For the first time in more than two decades, a team from the KEMRI-Wellcome Trust Research Programme and University of Oxford have quantified the risk of children suffering severe outcomes from malaria.

15 Sep 2021

The Indian second wave: SARS-CoV-2 infection-induced immunity could be ineffective in protecting population

Researchers decided to investigate how effective immunity gained from previous SARS-CoV-2 infection protects a wider community from disease.

15 Sep 2021

SARS-CoV-2 variants show substantial differences in spike structure

To investigate the impact of these mutations, researchers performed cryo-electron microscopy analysis on the variants spike proteins to determine any structural changes.

15 Sep 2021

Natural SARS-CoV-2 infection induces more durable immunity than vaccination study suggests

Scientists from the USA have demonstrated that immunity induced by mRNA-based COVID-19 vaccines in previously SARS-CoV-2-infected people has the highest robustness and durability with cross-reactivity against different viral variants.

15 Sep 2021

Vaccination of children before school reopening may control COVID-19 pandemic

A team has recently explored the impact of non-pharmaceutical control measures and vaccination on the COVID-19 pandemic during school reopening in England.

15 Sep 2021

Respiratory News and Research

COVID-19 and the gut-lung axis

Live oral SARS-CoV-2 vaccine provides partial protection in Rhesus Macaques

IL-1-Ra autoantibodies observed in high frequency in children with PIMS/MIS-C

New modeling on efficacy of BioNTech-Pfizer's SARS-CoV-2 vaccine against variants

Therapeutic potential of clinical-grade ACE2 for blocking SARS-CoV-2 variants

This 3D modeling reveals how SARS-CoV-2 attacks

Grants to promote COVID-19 vaccination among people with intellectual and developmental disabilities

Pfizer-BioNTech’s COVID-19 vaccine proves effective against recent SARS-CoV-2 variants

Link identified between early lower respiratory tract infections and development of OSA in children

Analysis of the immune landscape in mild-to-moderate COVID-19

Flavonoids can potentially help prevent COVID-19-induced diarrhea, study finds

Study looks at exposure to different SARS-CoV-2 variants and immune response

For My Lung Health campaign wins 2021 Pharmaceutical Executive APEX Awards

COVID mRNA vaccines display weakened immune response with age and diminish over time, according to new study

Phase I trial investigates using antiparasitic nitazoxanide for treatment of COVID-19

Researchers quantify the risk of children suffering severe outcomes from malaria

The Indian second wave: SARS-CoV-2 infection-induced immunity could be ineffective in protecting population

SARS-CoV-2 variants show substantial differences in spike structure

Natural SARS-CoV-2 infection induces more durable immunity than vaccination study suggests

Vaccination of children before school reopening may control COVID-19 pandemic

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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